教育背景
2013/09-2015/10,北卡罗来纳大学教堂山分校,联合培养博士
2009/09-2016/03,华中科技大学,博士
2005/09-2009/06,华中科技大学,药学院,本科
工作经历
2018/07-今,华中科技大学,药学院
2016/09-2018/02,昆士兰大学,AIBN
2016/04-2018/06,华中科技大学,基础医学院,博士后
项目课题经历
国家自然科学基金青年科学基金项目,81603046,铂类/免疫佐剂共载纳米粒诱导原位抗原产生用于治疗晚期黑色素瘤,在研,主持
2.湖北省自然科学基金面上项目,环境响应型金属纳米药物递送系统用于肿瘤免疫治疗,在研,主持
3.华中科技大学人才引进基金,2018-2021,在研,主持
4.国家自然科学基金青年科学基金项目,81703446, 氧化还原敏感性可降解多功能介孔硅纳米粒的构建及其抑制肿瘤干细胞逆转肿瘤耐药的作用研究,在研,参加
5.国家自然科学基金面上项目,81673368,新型脂包被顺铂/磷酸钙共载纳米粒抑制肝癌干细胞并协同治疗肝癌的实验研究,在研,参加
6.国家自然科学基金面上项目,81973257,在研,参加
论文、成果、著作等
(1) Yannan Yang#, Yao Lu #, et al. Stepwise degradable nanocarriers enabled cascade delivery for synergistic cancer therapy. Advanced Functional Materials, (2018), 28: 1800706. (共同第一作者) (IF=15.621)
(2) Yao Lu#, Yannan Yang#, et al. Glutathione-Depletion Mesoporous Organosilica Nanoparticles as a Self-Adjuvant and Co-delivery Platform for Enhanced Cancer Immunotherapy. Biomaterials. 2018,82-92. (IF= 10.273)
(3) Hao Song, Meihua Yu, Yao Lu, Zhengying Gu, et al. Plasmid DNA Delivery: Nanotopography Matters, Journal of the American Chemical Society, 2017, 139(50): 18247-18254. (IF=14.695)
(4) Yannan Yang#, Yao Lu#, Prasanna Lakshmi Abbaraju, et al. Multi‐shelled Dendritic Mesoporous Organosilica Hollow Spheres: Roles of Composition and Architecture in Cancer Immunotherapy, Angewandte Chemie, 2017, 129(29): 8566-8570 (共同第一作者) (IF=12.257)
(5) Yao Lu, Yuhua Wang, Lei Miao, Matthew Haynes, et al. Exploiting in situ antigen generation and immune modulation to enhance chemotherapy response in advanced melanoma: a combination nanomedicine approach, Cancer letters, 2016, 379(1): 32-38. (IF=6.508)
(6) Yao Lu, Lei Miao, Yuhua Wang, Zhenghong Xu, et al. Curcumin Micelles Remodel Tumor Microenvironment and Enhance Vaccine Activity in an Advanced Melanoma Model. Molecular Therapy. 2016. 24(2): 364-374 (IF=8.402)
(7) Yao Lu#, Nan Ding#, Chang Yang, Lei Huang L, Jian Liu, Guangya Xiang. Preparation and in vitro Evaluation of a Folate-Linked Liposomal Curcumin Formulation. Journal of Liposome Research. 2012, 22, 110-119.
(8) Nan Ding#,Yao Lu#, Robert J Lee#, Chang Yang, Lei Huang, Jian Liu, Guangya Xiang,Folate receptor targeted fluorescent paramagnetic bimodal liposomes for tumor imaging, International Journal of Nanomedicine,2011,6:2513-2520 (共同第一作者)
(9) Peng Ye, Wendian Zhang, Tan Yang, Yao Lu, Mao Lu, Yongkang Gai, Xiang Ma, Guangya Xiang. Folate receptor-targeted liposomes enhanced the antitumor potency of imatinib through the combination of active targeting and molecular targeting. International Journal of Nanomedicine. 2014, 9, 2167-2178
专利、著作版权等
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