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蔡晓凤

领域:生物产业 学校:华中科技大学职称:教授

微生物天然药物化学生物学与合成生物学...

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教育背景

2009.11-2013.10博士,德国波恩大学,生物学 (Prof. Dr. Jörn Piel)

2006.09-2009.06 硕士,华中师范大学,微生物学 (李爱英教授)

2003.10-2005.12 本科,山西大学,化学教育学

2002.09-2005.06 大专,长治学院,生物学教育

工作经历

2014.2-2018. 10博士后,德国法兰克福大学 (Prof. Dr. Helge B. Bode) 2018.10至今教授,华中科技大学,同济医学院药学院

项目课题经历

论文、成果、著作等

1.Hacker, C.,#Cai, X.,#Kegler, C.,Zhao, L., A., Weickhmann, A. K., Wurm, J. P., Bode, H. B.*and Wöhnert, J.* (2018). Structure-based redesign of docking domain interactions modulates the product spectrum of a rhabdopeptide-synthesizing NRPS.Nat. Com.9(1) DOI:10.1038/s41467-018-06712-1. (#, co-first author, IF: 12.353)

2.Cai, X., Nowak, Wesche, S.F., Bischoff, I., Kaiser, M., Fürst, R., andBode., H.B.* (2017).Entomopathogenic bacteria use multiple mechanisms for bioactive peptide library design.Nat. Chem. 9, 379-386.(IF: 26.201)

3.Cai, X.,#Shi, Y.M.,#Pöhlmann, N., Revermann, O., Bahner, I., Pidot, S.J., Wesche, F., Lackner, H., Büchel, C., Kaiser, M., Richter, C., Schwalbe, H., Stinear, T.P., Zeeck, A., and Bode, H.B.* (2017).Structure and biosynthesis of isatropolones, bioactive amine scavenging fluorescent natural products fromStreptomycesGö66.Angew. Chem. Int. Ed. Engl.56, 4945-4949.(#, co-first author, IF: 12.102)

4.Cai, X., Challinor, V.L., Zhao, L., Reimer, D., Adihou, H., Grün, P., Kaiser, M., and Bode., H.B.* (2017). Biosynthesis of the antibiotic nematophin and its elongated derivatives in entomopathogenic bacteria. Org. Lett.19, 806-809.(IF: 6.492)

5.Cai, X.,Teta, R., Kohlhaas, C., Crüsemann, M., Ueoka, R., Mangoni, A., Freeman, M.F.,* and Piel,J.* (2013). Manipulation of regulatory genes reveals complexity and fidelity in hormaomycin biosynthesis.Chem. Biol.20, 839-846. (IF: 6.743)

专利、著作版权等

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