1991年获日本九州大学医学博士学位

Huang M, Shen A, Ding J*, Geng M*, Molecularly targeted cancer therapy: some lessons from the past decade. Trends Pharmacol Sci.

Xie H, Lee MH, Zhu F, Reddy K, Lubet RA, Ding J, Bode AM, Dong Z*. Identification of an Aurora kinase inhibitor specific for the Aurora B isoform. Cancer Research

Xie H, Lee MH, Zhu F, Reddy K, Lubet R A., Ding J, AM Bode, Dong Z*.Discovery of the novel mTOR inhibitor and its antitumor activities in vitro and in vivo. Molecular Cancer Therapeutics

Huang X, Pan Q, Sun D, Chen W, Shen A, Huang M, Ding J*, Geng M. O-GlcNAcylation of cofilin promotes breast cancer cell invasion. J Biol Chem.

Ye N, Chen CH, Chen T, Song Z, He JX, Huan XJ, Song SS, Liu Q, Chen Y, Ding J, Xu Y, Miao ZH, Zhang A. Design, Synthesis, and Biological Evaluation of a Series of Benzo[de][1,7]naphthyridin-7(8H)-ones Bearing a Functionalized Longer Chain Appendage as Novel PARP1 Inhibitors. J Med Chem

Zhang X, Su M, Chen Y, Li J, Lu W. The design and synthesis of a new class of RTK/HDAC dual-targeted inhibitors. Molecules.

Wang X, Chen Z, Tong L, Tan S, Zhou W, Peng T, Han K, Ding J, Xie H, Xu Y. Naphthalimides exhibit in vitro antiproliferative and antiangiogenic activities by inhibiting both topoisomerase II (topo II) and receptor tyrosine kinases (RTKs).Eur J Med Chem

Zhao Y, Zhang X, Chen Y, Lu S, Peng Y, Wang X, Guo C, Zhou A, Zhang J, Luo Y, Cheng Q, Ding J, Meng LH*, Zhang J. Crystal structures of PI3Kα complexed with PI103 and Its derivatives: new directions for inhibitors design. ACS Medicinal Chemistry Letters.

Wang J, Wang X, Chen Y, Chen S，Chen G，Tong L, Meng LH*, Xie Y, Ding J*, and Yang C*. Discovery and bioactivity of 4-(2-arylpyrido[3',2':3,4]pyrrolo [1,2-f][1,2,4] triazin-4-yl) morpholine derivatives as novel PI3K inhibitors. Bioorg. Med. Chem. Lett.

Chen G, Chen SM, Wang X, Ding XF, Ding J*, Meng LH*. Inhibition of Chemokine (CXC Motif) Ligand 12/Chemokine (CXC Motif) Receptor 4 Axis CXCL12/CXCR4)-mediated Cell Migration by Targeting Mammalian Target of Rapamycin (mTOR) Pathway in Human Gastric Carcinoma Cells. J Biol Chem.

Chen SM, Liu JL, Wang X, Liang C, Ding J*, Meng LH*. Inhibition of tumor cell growth, proliferation and migration by X-387, a novel active-site inhibitor of mTOR. Biochem Pharmacol

Zhou ZL, Yang YX, Ding J, Li YC*, Miao ZH*. Triptolide: structural modifications, structure-activity relationships, bioactivities, clinical development and mechanisms. Nat Prod Rep

Liu HB, Zhang H, Yu JH, Xu CH, Ding J, Yue JM*. Cytotoxic Diterpenoids from Sapium insigne. J Nat Prod.

Yu B,Li MH, Wang W, Wang YQ, Jiang Y, Yang SP, Yue JM, Ding J*, Miao ZH*. Pseudolaric acid B-driven phosphorylation of c-Jun impairs its role in stabilizing HIF-1alpha: a novel function-converter model. J Mol Med (Berl).

Manzo SG, Zhou ZL, Wang YQ, Marinello J, He JX, Li YC, Ding J, Capranico J, Miao ZH. Natural product triptolide mediates cancer cell death by triggering CDK7-dependent degradation of RNA polymerase II. Cancer Res.

Zeng LF, Wang Y, Kazemi R, Xu S, Xu ZL, Sanchez TW, Yang LM, Debnath B, Odde S, Xie H, Zheng YT, Ding J, Neamati N, Long YQ.Repositioning HIV-1 Integrase Inhibitors for Cancer Therapeutics: 1,6-Naphthyridine-7-carboxamide as a Promising Scaffold with Drug-like Properties. J Med Chem

Feng JM, Miao ZH, Jiang Y, Chen Y, Li JX, Tong LJ, Zhang J, Huang YR, Ding J.Characterization of the conversion between CD133 (+) and CD133 (-) cells in colon cancer SW620 cell line. Cancer Biol The

Wang S, Huang X, Sun D, Xin X, Pan Q, Peng S, Liang Z, Luo C, Yang Y, Jiang H, Huang M, Chai W, Ding J*, Geng M. Extensive crosstalk between O-GlcNAcylation and phosphorylation regulates Akt signaling. PLoS One. [2]

相关成果申请国内外专利180余项，其中获国内外专利授权近60项