教育背景
工作经历
现任北京大学药学院教授、博士生导师
项目课题经历
承担了国家重大科技专项(863)、国家重大科学研究计划(973)课题、国家自然科学基金、北京市自然科学基金重点项目、教育部回国人员启动基金及博士点基金等二十多项纵向基金课题
论文、成果、著作等
1. Mu LM, Ju RJ, Liu R, Bu YZ, Zhang JY, Li XQ, Zeng F, Lu WL*. Dual-functional drug liposomes in treatment of resistant cancers. Adv Drug Deliv Rev. 2017 Jun 1;115: 46-56.
2. Liu L, Mu LM, Yan Y. Wu JS, Hu YJ, Bu YZ, Zhang JY, Liu R, Li XQ, Lu WL*. The use of functional epirubicin liposomes to induce programmed death in refractory breast cancer.Int J Nanomed. 2017 Jun 1;12:4163-4176.
3. Mu LM, Bu YZ, Liu L, Xie HJ, Ju RJ, Wu JS, Zeng F, Zhao Y, Zhang JY, Lu WL*. Lipid vesicles containing transferrin receptor binding peptide TfR-T12 and octa-arginine conjugate stearyl-R8 efficiently treat brain glioma along with glioma stem cells. Sci Rep. 2017 Jun 14;7(1):3487
4. Zhao WY, Zhang CX, Liu L, Mu LM, Zeng F, Ju RJ, Xie HJ, Yan Y, Zhao Y. Lu WL*. Construction of functional targeting daunorubicin liposomes used for eliminating brain glioma and glioma stem cells. J Biomed Nanotech. 2016; 12(1):1-16.
5. Ju RJ, Li XT, Shi JF, Li XY, Sun MG, Zeng F, Zhou J, Liu L, Zhang CX, Zhao WY, Lu WL*. Liposomes, modified with PTDHIV-1 peptide, containing epirubicin and celecoxib, to target vasculogenic mimicry channels in invasive breast cancer. Biomaterials. 2014;35(26):7610-21.
6. Ma X, Zhou J, Zhang CX, Li XY, Li N, Ju RJ, Shi JF, Sun MG, Zhao WY, Mu LM, Yan Y, Lu WL*. Modulation of drug-resistant membrane and apoptosis proteins of breast cancer stem cells by targeting berberine liposomes. Biomaterials.2013; 34(18):4452-65.
7. Li N, Zhang CX, Wang XX, Zhang L, Ma X, Zhou J, Ju RJ, Li XY, Zhao WY, Lu WL*. Development of targeting lonidamine liposomes that circumvent drug-resistant cancer by acting on mitochondrial signaling pathways. Biomaterials. 2013;34(13):3366-80
8. Zhang L, Yao HJ, Yu Y, Zhang Y, Li RJ, Ju RJ, Wang XX, Sun MG, Shi JF, Lu WL*. Mitochondrial targeting liposomes incorporating daunorubicin and quinacrine for treatment of relapsed breast cancer arising from cancer stem cells. Biomaterials. 2012 Jan;33(2):565-82.
9. Li RJ, Ying X, Zhang Y, Ju RJ, Wang XX, Yao HJ, Men Y, Tian W, Yu Y, Zhang L, Huang RJ, Lu WL*. All-trans retinoic acid stealth liposomes prevent the relapse of breast cancer arising from the cancer stem cells. J Control Release. 2011; 149:281-291
10. Ying X, Wen H, Lu WL*, Du J, Guo J, Tian W, Men Y, Zhang Y, Li RJ, Yang TY, Shang DW, Lou JN, Zhang LR, Zhang Q. Dual-targeting daunorubicin liposomes improve the therapeutic efficacy of brain glioma in animals. J Control Release. 2010; 141(2): 183-192
专利、著作版权等
获新药证书1项、新药临床研究批件4项;授权专利8项
声明:本站专家信息来源于各高校官网。