1993年上海中医药大学获医学博士学位

1997获日本长寿振兴财团基金，在WHO日本东京都老人综合研究所从事免疫研究工作

. 以外周a7nAChR为靶的镇痛抗炎药物研究

2. 活化a7nAChR/M4AchR后镇痛抗炎相关信号通路研究

3. 抗移植排斥药物及机制研究

4. 中药镇痛抗炎机制研究

5. 中药药性理论继承与创新研究

1. Hua Yang, Qi Sun, Yingying Liang ,Yimin Jiang, Runtao Li, Jia Ye*Antinociception of the spirocyclopiperazinium salt compound LXM-15 via activating α7 nAChR and M4 mAChR and inhibiting CaMKIIα/cAMP/CREB/CGRP signalling pathway in mice Regulatory Toxicology and Pharmacology 2018, 94: 108–114

2. Xiaoli Gao,Qi Sun,Weiwei Zhang, Yimin Jiang，Runtao Li,Jia Ye* Anti-inflammatory effect and mechanism of the spirocyclopiperazinium salt compound LXM-15 in rats and mice Inflammation research2018 67:363-370

3. Wei-Wei Zhang, Feng Xub, Ding Wang,Jia Ye*, Shao-Qing Cai* Buyang Huanwu Decoction ameliorates ischemic stroke by modulating multiple targets with multiple components in vitro Chinese Journal of Natural Medicines 2018, 16（3）: 194-202

4.Dan Wan, Ding Wang, Qi Sun, Yan Song, YiMin Jiang, RunTao Li, Jia Ye*. Antinociception of spirocyclopiperazinium salt compound LXM-10-M targeting α7 nicotinic receptor and M4 muscarinic recaptor and inhibiting CaMKII？/CREB/CGRP signaling pathway in mice.European Journal of Pharmacology 2016, 770: 92–98

5.Xiaoli Gao, Hua Yang,Yangguang Xu,Yulan Xiong, Guannan Wang, Xinshan Ye, Jia Ye*Iminosugar derivative WGN-26 suppresses acute allograft rejection via inhibiting the IFN-γ/p-STAT1/T-bet signaling pathway. International Immunopharmacology2014, 23: 688-695

6.Weiwei Zhang, Qi Sun, Xiaoli Gao, Yimin Jiang, Runtao Li, Jia Ye*，Anti-Inflammation of Spirocyclopiperazinium Salt Compound LXM-10 Targeting α7 nAChR and M4 mAChR and Inhibiting JAK2/STAT3 Pathway in Rats. PLOS ONE 2013, 8(6):1-8 (8: e66895)

7. Xia Zhao, Jia Ye*, Qi Sun, Yulan Xiong, Runtao Li and Yimin Jiang Antinociceptive effect of spirocyclopiperazinium salt compound LXM-15 via activating peripheral α7 nAChR and M4 mAChR in mice. Neuropharmacology 2011, 60:446-452

8.Song-Wen Lin, Qi Sun, Ze-Mei Ge, Xin Wang, Jia Ye*, Run-Tao Li*Synthesis and structure-analgesic activity relationships of a novel series of monospirocyclopiperazinium salts (MSPZ). Bioorganic & Medicinal Chemistry Letters 2011, 21: 940–943

9.Yulan Xiong, Xia Zhao, Qi Sun, Runtao Li, Changling Li, Jia Ye*，Antinociceptive mechanism of the spirocyclopiperazinium compound LXM-10 in mice and rats.Pharmacol. Biochem. Behav. 2010, 95:192–197

10.Yulan Xiong, Jia Ye*, Qi Sun, Xia Zhao, Runtao Li, Yimin Jiang, Anti-inflammatory effect of the spirocyclopiperazinium compound LXM-10 in mice and rats. European Journal of Pharmacology 2010, 626: 290–296

11.Guo-Liang Zhang, Changshui Chen, Yulan Xiong, Jia Ye*，Xin-Shan Ye*，Synthesis of N-substituted iminosugar derivatives and their immunosuppressive activities. Carbohydrate Research 2010, 345: 780–786

12.Deng-Bo Ji,Jia Ye*, Chang-Ling Li, Yu-Hua Wang, Jiong Zhao and Shao-Qing Cai Antiaging Effect of Cordyceps sinensis Extract. Phytotherapy Research2009, 23:116–122

13.Deng-Bo Ji, Jia Ye*, Yi-Min Jiang and Bo-Wen Qian Anti-tumor effect of Liqi, a traditional Chinese medicine prescription, in tumor bearing mice.BMC Complementary and Alternative Medicine 2009, 9:20

14. Deng Bo Ji, Chang Ling Li, Jia Ye*, Hai Bo Zhu* Effect of Hydroxysafflor yellow A on Human Umbilical Vein Endothelial Cells under hypoxia. Vascular Pharmacology 2009, 50: 137–145

15. Ji DB, Zhu MC, Zhu B, Zhu YZ, Li CL,Ye J*, Zhu HB*, Hydroxysafflor yellow A enhances survival of vascular endothelial cells under hypoxia via upregulation of the HIF-1 alpha-VEGF pathway and regulation of Bcl-2/Bax. J Cardiovasc Pharmacol 2008, 52 (2) :191-202

16. Deng Bo JI, Hai Bo ZHU, Jia YE*, Chang Ling LI* Establishment of a Cell-Based Assay to Screen Regulators of the Hypoxia-Inducible Factor-1-Dependent Vascular Endothelial Growth Factor promoter. Biol. Pharm. Bull. 2008, 31(12): 2255–2259

17. Cai-Qin Yue, Jia Ye*, Chang-Ling Li, Run-Tao Li, Qi Sun. Antinociceptive effects of the novel spirocyclopiperazinium salt compound LXM -10 in mice. Pharmacol. Biochem. Behav.2007, 86:643–650.

申请及授权世界专利4项和中国专利9项