2007年3月获京都大学理学博士学位

2008年8月加入中国科学院上海有机化学研究所任副研究员课题组长，独立开展研究工作，14年6月起任研究员。2016年任扬州大学特聘教授。

国家自然科学青年基金（20902099）：2010，01-2012，12，主持，

国家自然科学面上基金（21172238）：2012，01-2015，12，主持，

国家自然科学面上基金（21472218）：2015，01-2018，12，主持，

国家自然科学面上基金（21672183）：2017，01-2020，12，主持，

973手性催化的重要科学基础子课题（2010CB833302）：2010，01-2014，08，参与


本课题组着重在不对称催化合成手性膦化合物方向和过渡金属催化碳氢键活化方向上开展了研究工作。发展了一种钳形钯催化剂，实现了首例二芳基膦氢对不饱和烯酮及其他各种缺电子烯烃的高对映选择性1，4加成反应。所得各种高光学活性的手性膦化合物可被衍生化作为手性膦配体在不对称催化反应中进一步应用。在碳氢键活化反应方面，发展了双齿单负离子含氮配体，能实现无导向基团芳烃的碳氢键活化反应，以及发展了利用手性磷酰胺，磷酸控制不对称碳氢键活化反应的立体选择性的策略。

以通讯作者在包括J. Am. Chem. Soc.; Angew. Chem. Int. Ed.; Chem. Commun.; Org. Lett.等国际期刊上发表多篇研究论文。

26. Xu, B.-B.; Ye, J.; Yuan, Y.; Duan, W.-L.* Palladium-Catalyzed Asymmetric C−H Arylation for the Synthesis of Planar Chiral Benzothiophene-Fused Ferrocenes. ACS Catalysis 2018, 8, 11735.

25. Li, Z.; Duan, W.-L.* Palladium-Catalyzed C-H Alkenylation of Arenes with Alkynes: Stereoselective Synthesis of Vinyl Chlorides via a 1,4-Chlorine Migration. Angew. Chem. Int. Ed. 2018, 57, 16041.

24. Dai, G.-F.; Song, Y.-C.; Xoap, F.;* Duan, W.-L.* Palladium-Catalyzed Asymmetric 1,4-Addition of Diarylphosphines to α,β-Unsaturated Sulfonamides. Synthesis 2018, 50, 3506.

23. Zhu, T.; Li, Z.; Xiao, F.;* Duan, W.-L.* Pd-catalyzed oxidative homo-coupling of acrylates and aromatic alkenes for the conjugated diene synthesis. Tetrhedron Lett. 2018, 59, 3238.

22. Wei, X.; Duan, W.-L.* Palladium-Catalyzed Asymmetric 1,6-Addition of Diarylphosphines to Allylidenemalonates for Chiral Phosphine Synthesis. Synthesis 2016, 48, 4155.

21. Zhu, T.; Li, Z.; Xiao, F.;* Duan, W.-L.* Palladium-catalyzed enantioselective hydrophosphination of enones for the synthesis of chiral P,N-compounds. Tetrhedron Lett. 2016, 57, 2990.

20. Li, Z.; Duan, W.-L.* Recent Advances in the Asymmetric Conjugate Addition Reactions of Phosphorus Nucleophiles to Electron-Deficient Alkenes. Chin. J. Org. Chem. 2016, 36, 1805.

19. Zhang, S.; Lu, J.; Ye, J.;* Duan, W.-L.* Asymmetric C—H Arylation for the Synthesis of Planar Chiral Ferrocenes: Controlling Enantioselectivity Using Chiral Phosphoric Acids. Chin. J. Org. Chem. 2016, 36, 752.

18 Lin, Z.-Q.; Wang, W.-Z.; Yan, S.-B.; Duan, W.-L.*. Palladium-Catalyzed Enantioselective C–H Arylation for the Synthesis of P-Stereogenic Compounds. Angew. Chem. Int. Ed. 2015, 54, 6265.

17 Yan,S.-B.; Zhang, S.; Duan, W.-L.* Palladium-Catalyzed Asymmetric Arylation of C(sp3)–H Bonds of Aliphatic Amides: Controlling Enantioselectivity Using Chiral Phosphoric Amides/Acids. Org. Lett. 2015, 17, 2458.

16. Ying, C.-H.; Duan, W.-L.* Palladium-Catalyzed Direct C–H Allyation of Arenes without Directing Groups, Org. Chem. Front. 2014, 1, 546.

15. Li, C.; Li, W.-X.; Xu, S.; Duan, W.-L.* Palladium-Catalyzed 1,4-Addition of Secondary AlkylphenylPhosphines to α,β-Unsaturated Carbonyl Compounds for the Synthesis of Phosphorus- and Carbon-Stereogenic Compounds. Org. Chem. Front. 2014, 1, 541.

14. Chen, Y.-R.; Duan, W.-L.* Palladium-Catalyzed Intramolecular Direct Arylation for Phosphorus Heterocycle Synthesis. Synthesis. 2014, 46, 1067.

13. Ying, C.-H.; Yan, S.-B.; Duan, W.-L.* 2-Hydroxy-1,10-phenanthroline vs 1,10-Phenanthroline: Significant Ligand Acceleration Effects in the Palladium-Catalyzed Oxidative Heck Reaction of Arenes. Org. Lett. 2014, 16, 500.

12. Huang, J.; Zhao, M.-X.; Duan, W.-L.* Palladium-Catalyzed Asymmetric 1,6-Addition of Diphenylphosphine to (4-Aryl-1,3-butadienylidene)bis(phosphonates) for the Synthesis of Chiral Phosphines. Tetrahedron: Lett. 2014, 55, 629.

11. Chen, Y.-R.; Feng, J.-J.; Duan, W.-L.* NHC–Copper-Catalyzed Asymmetric 1,4-Addition of Diarylphosphines to α,β-Unsaturated Ketones. Tetrahedron: Lett. 2014, 55, 595.

10. Lu, J.; Ye, J.; Duan, W.-L.* Palladium-Catalyzed Asymmetric 1,6-Addition of Diarylphosphines to a,ß,c,d-Unsaturated Sulfonic Esters: Controlling Regioselectivity by Rational Selection of Electron-Withdrawing Groups. Chem. Commun. 2014, 50, 698.

9. Chen, Y.-R.; Duan, W.-L.* Silver-Mediated Oxidative C–H/P–H Functionalization: An Efficient Route for the Synthesis of Benzo[b]phosphole Oxides. J. Am. Chem. Soc. 2013, 135, 16754.

8. Lu, J.; Ye, J.; Duan, W.-L.* Palladium-Catalyzed Asymmetric Addition of Diarylphosphines to α,β-Unsaturated Sulfonic Esters for the Synthesis of Chiral Phosphine Sulfonate Compounds. Org. Lett. 2013, 15, 5016.

7. Li, C.; Li, W.-X.; Xu, S.; Duan, W.-L.* Pd-Catalyzed Asymmetric Alkylation of Methylphenylphosphine with Alkyl Halides for the Synthesis of P-stereogenic Compounds. Chin. J. Org. Chem. 2013, 33, 799.

6. Du, D.; Lin, Z.-Q.; Lu, J.-Z.; Li, C.; Duan, W.-L.* Palladium-Catalyzed Asymmetric 1,4-Addition of Diarylphosphines to α,β-Unsaturated Carboxylic Esters. Asian J. Org. Chem. 2013, 2. 392.

5. Huang, M.; Li, C.; Duan, W.-L.*; Xu, S. Palladium-Catalyzed Asymmetric Addition of Diarylphosphines to N-tosylimines. Chem. Commun. 2012, 48, 11148.

4. Feng, J.-J.; Huang, M.; Lin, Z.-Q. Duan, W.-L.* Palladium-Catalyzed Asymmetric 1,4-Addition of Diarylphosphines to Nitroalkenes for the Synthesis of Chiral P,N-Compounds. Adv. Synth. Catal. 2012, 354, 3122.

3. Chen, Y.-R.; Duan, W.-L.* Palladium-Catalyzed 1,4-Addition of Diarylphosphines to α,β-Unsaturated Aldehydes. Org. Lett. 2011, 13, 5824.

2. Du, D.; Duan, W.-L.* Palladium-Catalyzed 1,4-Addition of Diarylphosphines to α,β-Unsaturated N-Acylpyrroles. Chem. Commun. 2011, 47, 11101.

1. Feng. J.-J.; Chen. X.-F.; Shi, M.; Duan, W.-L.* Palladium-Catalyzed Asymmetric Addition of Diarylphosphines to Enones toward the Synthesis of Chiral Phosphines J. Am. Chem. Soc. 2010, 132, 5562.