2001年08月-2004年07月： 中科院上海有机所，有机化学，博士
1998年09月-2001年06月： 中国药科大学，药物化学，硕士
1994年09月-1998年06月： 中国药科大学，化学制药，学士

2008年01月-：中国药科大学，药物化学系教授 2004年09月-2007年11月： 美国斯坦福大学, 化学生物学，博士后

1. 国家“重大新药创制”科技重大专项（候选药物）（2009ZX09103-128）
2. 国家自然科学基金(20902111、21272276、21572272)
3. 教育部新世纪优秀人才支持计划 （NCET-2008)
4. 教育部霍英东基金基础性研究课题（121040）

1. Shang GaoФ, Hao LiuФ, Chi Yang, Zhiyuan Fu, Hequan Yao*, Aijun Lin*. Accessing 1,3-Dienes via Palladium-Catalyzed Allylic Alkylation of Pronucleophiles with Skipped Enynes. Org. Lett. 2017, Accepted. (IF 6.579) (Ф equal contribution)
2. Zhenbo YuanФ, Rui PanФ, He Zhang, Lina Liu, Aijun Lin*, Hequan Yao*, Palladium-catalyzed Oxa-[4+2] Annulation of para-Quinone Methides" submitted online to Advanced Synthesis & Catalysis. Adv. Synth. Catal. 2017, Accepted. (IF 5.646) (Ф equal contribution)
3. Jichao Chen, Ruifang Wang, Tianyu Wang, Qilong Ding, Aliahmad Khalil, Shengtao Xu, Aijun Lin, Hequan Yao*, Weijia Xie, Zheying Zhu*, Jinyi Xu*. Antioxidant Properties of Novel Dinners Derived from Natural beta-Elemene through Inhibiting H2O2-Induced Apoptosis. ACS Med. Chem. Lett. 2017, 8(4), 443-448. (IF 3.746)
4. Shengtao Xu, Hong Yao, Shanshan Luo, Yun-Kai Zhang, Dong-Hua Yang, Dahong Li, Guangyu Wang. Mei Hu, Yangyi Qin, Hequan Yao*, Xiaoming Wu, Zhe-sheng Chen*, Jinyi Xu*. A potent anticancer agent optimized from natural oridonin scaffold induces apoptosis and cell cycle arrest through the mitochondrial pathway. J. Med. Chem. 2017, 60，1449-1668. (IF 6.259)
5. Shang Gao, Hao Liu, Zijun Wu, Hequan Yao*, Aijun Lin*. Palladium-Catalyzed Allylic Alkylation with Internal Alkynes to Construct C-C and C-N Bonds in Water. Green Chem. 2017, 19(8), 1861-1865. (IF 9.125)
6. Zhenbo Yuan, Kuo Gai, Youzhi Wu, Jie Wu, Aijun Lin, Hequan Yao*. Tandem 1,6-Addition/Cyclization/Vinylcyclopropane Rearrangement at Low Temperature under Metal-free Conditions: An Approach to Spiro[4.5]cyclohexadienones. Chem. Comm. 2017, 53, 3485-3488. (IF 6.319)
7. Jiuan zheng, Panpan Li, Aijun Lin*, Hequan Yao*. Synthesis of Spiropentadiene Pyrazolones by Rh(III)-Catalyzed C-H Activation/Annulation. Org. Lett. 2017, 19(11), 2829-2832. (IF 6.579)
8. Peng Sun, Shang Gao, Chi Yang, Songjin Guo, Aijun Lin*, Hequan Yao*. Controllable Rh(III)-Catalyzed Annulation between Salicylaldehydes and Diazo Compounds: Divergent Synthesis of Chromenes and Benzofurans. Org. Lett. 2016, 18, 6464-6467. (IF 6.732)
9. Shang Gao, Zijun Wu, Fei Wu, Aijun Lin*, Hequan Yao*. Catalyst-controlled Regiodivergent Dehydrogenative Heck Reaction of 4-Aryl Thiophene/Furan-3-Carboxylates. Adv. Synth. Catal. 2016, 358, 4129-4135. (IF 6.453)
10. Chi Yang, Shang Gao, Hequan Yao*, Aijun Lin*. Rhodium-Catalyzed Hydroacylation of para-Quinone Methides with Salicylaldehydes: An Approach to alpha,alpha-Diarylated 2-Hydroxy Acetophenones. J. Org. Chem. 2016, 81, accepted. (IF 4.785)
11. Songjin Guo, Kai Yuan, Meng Gu, Aijun Lin*, Hequan Yao*. Rh(III)-Catalyzed Cascade Annulation/C-H Activation of o-Ethynylanilines with Diazo Compounds: One-Pot Synthesis of Benzo[a]carbazoles via 1,4-Rhodium Migration. Org. Lett. 2016, 18, 5236-5239. (IF 6.732)
12. Kaifang Zhang, Chi Yang, Hequan Yao*, Aijun Lin*. [3+2] Cycloaddition Reaction of in situ Formed Azaoxyallyl Cations with Aldehydes: a Facile Approach to Oxazolidin-4-ones. Org. Lett. 2016, 18, 4618-4621. (IF 6.732)
13. Shang GaoФ, Zijun WuФ, Xinxin Fang, Aijun Lin*, Hequan Yao*. Palladium-catalyzed Dearomative Allylic Alkylation of Indoles with Alkynes to Synthesize Indolenines with C3-Quarternary Centers. Org. Lett. 2016, 18, 3906-3909. (IF 6.732) (Ф equal contribution)
14. Zhenbo Yuan, Weiwei Wei, Aijun Lin*, Hequan Yao*. Bifunctional Organo/Metal Cooperatively Catalyzed [3+2] Annulation of Para-Quinone Methides with Vinylcyclopropanes: Approach to Spiro[4.5]deca-6,9-diene-8-ones. Org. Lett. 2016, 18, 3370-3373. (IF 6.732)
15. Xuanyi Li, Xiuyan Xu, Weiwei Wei, Aijun Lin*, Hequan Yao*. Organocatalyzed Asymmetric 1,6-conjugate Addition of para-Quinone Methides with Dicyanoolefins. Org. Lett. 2016, 18, 428-431. (IF 6.732)
16. Hui Jiang, Shang Gao, Jinyi Xu, Xiaoming Wu, Aijun Lin*, Hequan Yao*. Multiple Roles of Pyrimidyl Group in the Rh-Catalyzed Regioselective Synthesis and Functionalization of Indole-3-Carboxylic Acid Esters. Adv. Synth. Catal. 2016, 358, 188–194. (IF 6.453)
17. Youzhi Wu, Peng Sun, Kaifan Zhang, Tie Yang, Hequan Yao*, Aijun Lin*. Rh(III)-catalyzed Redox-neutral Annulation of Primary Arylamides with Diazo Compounds: Approach to Isoquinolinones. J. Org. Chem. 2016, 81, 2166-2173. (IF 4.785)
18. Kuo Gai, Xinxin Fang, Xuanyi Li, Jinyi Xu, Xiaoming Wu, Aijun Lin*, Hequan Yao*. Synthesis of Spiro[2.5]octa-4, 7-dien-6-one via 1, 6-Conjugate Addition Induced Dearomatization of para-Quinone Methides with Bromomalonates. Chem. Commun. 2015, 51, 15831-15834. (IF 6.834)
19. Youla SuФ, Shang GaoФ, Yue Huang, Aijun Lin*, Hequan Yao*. Solvent- controlled C2/C5-regiodivergent alkenylation of pyrroles. Chem. Eur. J. 2015, 21, 15820-15825. (Ф equal contribution) (IF 5.731)
20. Xuanyi Li, Kuo Gai, Zhenbo Yuan, Jie Wu, Aijun Lin*, Hequan Yao*. Organocatalyzed formal [4+2] cycloaddition of in situ generated azoalkenes with aryl acetic acids: an efficient approach to the synthesis of 4, 5-dihydropyridazin-3(2H)-ones. Adv. Synth. Catal. 2015, 357, 3479–3484. (IF 5.663)
21. Peng SunФ, Youzhi WuФ, Jinyi Xu, Xiaoming Wu, Aijun Lin*, Hequan Yao*. Synthesis of Heterocycle-fused-Pyridine N-Oxides from Oximes and Diazo Compounds via Rh(III)-Catalyzed C-H Activation and Annulation. Adv. Synth. Catal. 2015, 357(11), 2469-2473. (Ф equal contribution) (IF 5.663)
22. Hengyuan Zhang, Yiwei Wang, Peiqing Zhu, Jie Liu, Shengtao Xu, Hequan Yao*, Jieyun Jiang, Wencai Ye, Xiaoming Wu, Jinyi Xu∗. Design, synthesis and antitumor activity of triterpenoid pyrazine derivatives from 23-hydroxybetulinic acid. Eur. J. Med. Chem. 2015, 88, 235-244. (IF 3.447)
23. Youla Su, Haipin Zhou, Jiaxuan Chen, Jinyi Xu, Xiaoming Wu, Aijun Lin*, Hequan Yao*. Solvent-controlled Switchable C-H Alkenylation of 4-Aryl 1H-pyrrole 3-carboxylates: Application to the Total Synthesis of (±)-Rhazinilam. Org. Lett. 2014, 16, 4884-4887. (IF 6.324)
24. Hengyuan Zhang, Peiqing Zhu, Jie Liu, Xue Yang, Shengtao Xu, Hequan Yao*, Jieyun Jiang, Wencai Ye, Xiaoming Wu, Jinyi Xu*. Synthesis and antitumor activity of novel 3-oxo-23-hydroxybetulinic acid derivatives. Eur. J. Med. Chem. 2014, 87, 159-167. (IF 3.432)
25. Ziyuan Li, Ling Ma, Jinyi Xu, Lingyi Kong, Xiaoming Wu, Hequan Yao*. Pd(II)-Catalyzed Direct C5-Arylation of Azole-4-carboxylates through Double C-H Bond Cleavage. Chem. Commun. 2012, 48(31), 3763-3765. (IF 6.378)
26. Lei Zhao, Ziyuan Li, Lin Chang, Jinyi Xu, Hequan Yao*, Xiaoming Wu*. Efficient Construction of Fused Indolines with 2-Quaternary Center via Intramolecular Heck Reaction with Low Catalyst Loading. Org. Lett. 2012, 14(8), 2066-2069. (IF 6.142)
27. Ying Kong, Hequan YaoФ, Hongjun RenФ, Selvakumar SubbianФ, Suat Cirillo, James Sacchettini, Jianghong Rao*, Jeffrey Cirillo*. Imaging tuberculosis with endogenous β-Lactamase reporter enzyme fluorescence in live mice. Proc Nat. Acad. Soc. 2010, 107(27), 12239-12244. (Фequal contribution). (IF 9.771)
28. Hequan Yao, Yuan Gao, Peng Liu, Bingfeng Sun, Xingxiang Xu*. Asymmetric synthesis of the diene unit of Methyl sartortuoate via a temperature sensitive intramolecular Horner-Wadsworth-Emmons (HWE) reaction. Synlett 2007, (4), 571-574. (IF 2.763)
29. Hequan YaoФ, Min-Kyung SoФ, Jianghong Rao*. A bioluminogenic substrate for in vivo imaging of β-lactamase activity. Angew. Chem. Int. Ed. 2007, 46(37), 7031-7034. (Фequal contribution). (IF 10.031)
30. Hequan Yao, Yan Zhang, Fei Xiao, Zuyong Xia, Jianghong Rao*. A QD-BRET-based highly sensitive detection of protease. Angew. Chem. Int. Ed. 2007, 46(23), 4346-4349. (IF 10.031