本科、硕士、博士分别毕业于中国药科大学化学制药、药物化学及制药工程专业

英国谢菲尔德大学（University of Sheffield）交流访问一年

主持国家自然科学基金等多项纵向课题，参与国家“新药重大创制”等国家、省部级项目；承担多项企业合作项目

1) Zhao Yang, Chengkou Liu, Yu Zeng, Jingming Zhang, Zhixiang Wang, Zheng Fang, Kai Guo. Cu-catalyzed β-functionalization of saturated ketones with indoles a one-step synthesis of C3-substituted indoles. RSC Adv, 2016, 6, 89181-89184.

(2) Zhao Yang, Zheng Fang, Wei He, Zhixiang Wang, Haifeng Gan, Qitao Tian, Kai Guo. Identification of inhibitors for vascular endothelial growth factor receptor by using dynamic combinatorial chemistry.Bioorg Med Chem Lett,2016, 26, 1671-1674.

(3) Zhao Yang, Zheng Fang, Zhixiang Wang, Kai Guo. A Novel Synthetic Method for 1-(2,4-Dichlorophenyl)-4-methyl-5-(4- chlorophenyl)-1H-pyrazole-3-carboxylic Acid. Chin J Org Chem, 2013, 33, 607-610.

(4) Chengkou Liu, Zhao Yang, Yu Zeng, Kai Guo, Zheng Fang, Bo Li. Sodium nitrite-promoted aerobic oxidative coupling of aryl methyl ketones with ammonium under metal-free conditions: a facile access to polysubstitution imidazoles. Org Chem Front,2017, 4, 1508-1512.

(5) Chengkou Liu, Zhao Yang, Yu Zeng, Zheng Fang, Kai Guo. Chemoselective C(a)-C(b) bond cleavage of saturated aryl ketones with amines leading to a-ketoamides: a copper-catalyzed aerobic oxidation process with air. Org Chem Front, 2017, 4, 2375-2379.

(6) Chengkou Liu, Zhao Yang, Yu Zeng, Zheng Fang*, Kai Guo*. Metal-free aminocatalytic oxidative synthesis of polysubstitution imidazoles from aryl methyl ketones, ammonium or benzylamine, and hydrogen peroxide. Asian J Org Chem, 2017, 6(8), 1104-1109.

(7) Zheng Fang, Zhao Yang, Dong Ji, Ning Zhu, Xin Li, Li Wan, Kai Zhang, Kai Guo. Novel synthesis of a soy-based polyol for polyurethane rigid foam. RSC Adv, 2016, 6, 90771-90776.

(8) Chengkou Liu, Zhao Yang, Shiyu Guo, Yu Zeng, Ning Zhu, Xin Li, Zheng Fang, Kai Guo.Copper-TEMPO-catalyzed synthesis of alpha-ketoamides via tandem sp(3)C-H aerobic oxidation and amination of phenethyl alcohol derivatives. Org Biomol Chem, 2016, 14, 8570-8575.

(9) Jiawei Hua, Shiyu Gu, Zhao Yang, Zheng Fang, Kai Guo. Microfluidic synthesis of tert-butyl peresters via KI-catalyzed oxidative coupling of methyl arenes and tert-butyl hydroperoxide. Org Process Res Dev, 2017, 21 (10), 1633-1637.

(10) Shiyu Guo, Jiawei Hua, Zhongxue Dai, Zhao Yang, Zheng Fang, Kai Guo. Two-Step Continuous Synthesis of Dicarbonyl Indoles via I2/DMSO Promoted Oxidative Coupling: A Green and Practical Approach to Valuable Diketones from Aryl Acetaldehydes. ACS Sustainable Chem Eng, 2018, DOI: 10.1021/acssuschemeng.8b01339.

申请中国发明专利十余项，目前已授权八项