2008年毕业于中国药科大学药物分析学专业获理学博士学位

2008-2012年先后在新加坡国立大学医学院和公共卫生学院从事博士后（Research Fellow）研究工作；2018年入选首批澳门大学濠江杰出访问学者（The UM Macao Distinguished Visiting Scholar）

主持国家自然科学基金项目（81773682、81573385、81302733）、教育部科学技术研究重大项目（113036A）、“十三五”重大新药创制科技重大专项（2017ZX09101001-004-004）等国家及省部级科研项目8项；作为主要成员参与国家自然科学基金、江苏省自然科学基金、国家中医药局中医药行业科研专项、澳门科技发展基金等科研项目10余项；主持（含共同主持）江苏省研究生教育教学改革课题重点项目3项、江苏省学位与研究生教育学会学位授予质量研究课题1项，指导国家级大学生创新创业训练计划和江苏省高校研究生科技创新计划8项。

[1].Yiqiao Gao, Wei Li, Jiaqing Chen, Xu Wang, Yingtong Lv, Yin Huang, Zunjian Zhang*, and Fengguo Xu*. Pharmacometabolomic prediction of individual differences of gastrointestinal toxicity complicating myelosuppression in rats induced by Irinotecan. Acta Pharm Sin B 2018 in press （SCI, IF: 6.014）

[2].Ruiqi Jiang, Yu Jiao, Pei Zhang, Yong Liu, Xu Wang, Yin Huang, Zunjian Zhang*, Fengguo Xu*. Twins Derivatization Strategy for High-Coverage Quantification of Free Fatty Acids by Liquid Chromatography-Tandem Mass Spectrometry. Anal Chem. 2017 89：12223-12230 （SCI, IF: 6.32）

[3].Jiaqing Chen, Pei Zhang, Mengying Lv, Huimin Guo, Yin Huang, Zunjian Zhang*, Fengguo Xu*. Influences of Normalization Method on Biomarker Discovery in Gas Chromatography–Mass Spectrometry Based Untargeted Metabolomics: What Should be Considered? Anal Chem. 2017 89(10):5342-5348（SCI, IF: 6.32）

[4].Pei Zhang, Wei Li, Jiaqing Chen, Ruiting Li, Zunjian Zhang, Yin Huang*, Fengguo Xu*. Branched-Chain Amino Acids as Predictors for Individual Differences of Cisplatin Nephrotoxicity in Rats: A Pharmacometabonomics Study. J Proteome Res 2017 16(4):1753-1762 （SCI, IF:4.173）

[5].Huimin Guo, Yu Jiao, Xu Wang, Tao Lu, Zunjian Zhang*, Fengguo Xu*. Twins labeling-liquid chromatography/mass spectrometry (TL-LC/MS) based metabolomics for absolute quantification of tryptophan and its key metabolites. J Chromatogr A 2017 1504:83-90. （SCI, IF:3.926）

[6].Yiran Yao, Pei Zhang, Jing Wang, Jiaqing Chen, Yong Wang, Yin Huang, Zunjian Zhang*, Fengguo Xu*. Dissecting target toxic tissue and tissue specific responses of irinotecan in rats using metabolomics approach. Front Pharmacol. 2017 8:122（SCI, IF:4.418）

[7].Dongni Cui, Xu Wang, Jiaqing Chen, Bo Lv, Pei Zhang, Wei Zhang, Zunjian Zhang*, Fengguo Xu*. Quantitative evaluation of the compatibility effects of Huangqin decoction on the treatment of irinotecan-induced gastrointestinal toxicity using untargeted metabolomics. Front Pharmacol. 2017 DOI: 10.3389/fphar.2017.00211（SCI, IF:4.418）

[8].Fengguo Xu, Tavintharan S, Kaing Woon, Su Chi Lim, Chee Fang Sum, Choon Nam Ong, Metabolic Signature Shift in Type 2 Diabetes Mellitus Revealed by Mass Spectrometry-based Metabolomics, J Clin Endocr Metab 2013 98(6):E1060-5 (SCI, IF:6.43)

[9].Fengguo Xu, Li Zou, Ying Liu, Zunjian Zhang*, Choon Nam Ong*. Enhancement of the capabilities of liquid chromatography-mass spectrometry with derivatization: General principles and applications, Mass Spectrom Rev, 2011;30(6):1143-72 (SCI，IF: 10.46)

[10].Fengguo Xu, Li Zou, Choon Nam Ong*. Experiment-originated variations, multi-peak and multi-origination phenomena in derivatization-based GC/MS metabolomics. TrAC-Trends Anal Chem. 2010 29: 269-280 (SCI，IF: 6.546)

[11].Fengguo Xu, Li Zou, Choon Nam Ong*.Multi-origination of chromatographic peaks in derivatized GC/MS metabolomics: A confounder that influences metabolic pathway interpretation. J Proteome Res, 2009 8(12):5657-65 (SCI，IF: 5.132)