2007/09-2011/07中国药科大学，中药学，理学学士学位

2011/09-2016/07中国科学院昆明植物研究所，植物化学与西部植物资源持续利用国家重点实验室，药物化学，理学博士学位

2012/09-2014/01中国科学院上海生物化学与细胞生物学研究所，细胞生物学国家重点实验室，合作研究 2014/08-2015/01四川大学，生物治疗国家重点实验室，合作研究 2016/10-至今中国药科大学，中药学院 2017/03-2017/05香港中文大学，中医中药研究所，合作研究

1. Li Feng†, Jia Wang†, Shui Liu, Xue-Jia Zhang, Qi-Rui Bi, Yan-Yun Hu, Zhe Wang*, Ning-Hua Tan*. Colletopeptides A-D, anti-inflammatory cyclic tridepsipeptides from the plant endophytic fungus Collectotrichum sp. S8.Journal of Natural Products, 2019,82, 1434−1441.

2. Yan-Yun Hu†, Li Feng†, Jia Wang, Xue-Jia Zhang, Zhe Wang*, Ning-Hua Tan*. Rubipodanin B, a new cytotoxic cyclopeptide from Rubia podantha.Chemisty & Biodiversity, 2019, 16, e1800438.

3. Zhe Wang†, Si-Meng Zhao†, Li-Hua Song†, Yu-Zhi Pu, Qiang Wang, Guang-Zhi Zeng, Xing Liu, Ming Bai, Shao Li, Fa-Bao Gao, Li-Juan Chen*, Chen Wang*, Ning-Hua Tan*. Natural cyclopeptide RA-V inhibits the NF-κB signaling pathway by targeting TAK1.Cell Death & Disease, 2018, 9: 715.

4.Zhe Wang†, Si-Meng Zhao†, Yan-Yun Hu†, Li Feng, Li-Mei Zhao, Ying-Tong Di, Ning-Hua Tan*. Rubipodanones A-D, cytotoxic naphthohydroquinone dimers from the roots and rhizomes of Rubia podantha.Phytochemistry,2018, 145: 153-160.

5. Guang-Zhi Zeng†, Zhe Wang†, Li-Mei Zhao, Jun-Ting Fan, Ning-Hua Tan*. NF-κB and JNK mediated apoptosis and G0/G1 arrest of HeLa cells induced by rubiarbonol G, an arborinane-type triterpenoid from Rubia yunnanensis. Journal of Ethnopharmacology, 2018, 230, 220-227.

6. Sen-Lin Li†, Ze Hong†, Zhe Wang†, Fei Li†, Jia-Hao Mei, Lu-Lu Huang, Xi-Wen Lou, Si-Meng Zhao, Li-Hua Song, Wei Chen, Qiang Wang, Heng, Liu, Yan-Ni Cai, Huan-Sha Yu, Hui-Min Xu, Guang-Zhi Zeng, Quan-Yi Wang, Juan-Juan Zhu, Xing Liu*, Ning-Hua Tan*, Chen Wang*. The cyclopeptide astin C specifically inhibits the innate immune CDN sensor STING. Cell Reports, 2018, 25, 3405-3421.

7.Si-Meng Zhao†, Zhe Wang†, Xiao-Qiang Chen, Mao-Bo Huang, Ning-Hua Tan*. (±)-Rubioncolin D, a pair of enantiomeric naphthohydroquinone dimers from Rubia oncotricha. Tetrahedron Letters, 2017, 58, 3041-3043.

8. Li-Hua Song†, Zhe Wang†, Yu-Rong Wang, Di Guo, Jian-Hong Yang, Li-Juan Chen, Ning-Hua Tan*. Natural cyclopeptide RA-XII, a new autophagy inhibitor, suppresses protective autophagy for enhancing apoptosis through AMPK/mTOR/P70S6K pathways in HepG2 cells. Molecules, 2017, 22, 1934.

9.Hoi-Wing Leung†, Zhe Wang†, Grace Gar-Lee Yue, Si-Meng Zhao, Julia Kin-Ming Lee, Kwok-Pui Fung, Ping-Chung Leung, Clara Bik-San Lau*, Ning-Hua Tan*. Cyclopeptide RA-V inhibits cell adhesion and invasion in both estrogen receptor positive and negative breast cancer cells via PI3K/AKT and NF-κB signaling pathways. Biochimica et Biophysica Acta-Molecular Cell Research, 2015, 1853, 1827-1840.

10.Zhe Wang†, Si-meng Zhao†, Li-mei Zhao, Xiao-qiang Chen, Guang-zhi Zeng*, Ning-hua Tan*. Rubipodanin A, the first natural N-desmonomethyl Rubiaceae-type cyclopeptide from Rubia podantha, indicating an important role of the N9-methyl group in the conformation and bioactivity. PLoS ONE 2015, 10, e0144950.

11.Si-Meng Zhao†, Zhe Wang†, Guang-Zhi Zeng*, Wei-Wu Song, Xiao-Qiang Chen, Xiao-Nian Li, Ning-Hua Tan*. New cytotoxic naphthohydroquinone dimers from Rubia alata. Organic Letters, 2014, 16, 5576-5579.

参与授权专利3项