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涂家生

领域:生物产业 学校:中国药科大学职称:教授

从事药用辅料、药物制剂和药物传递技术等研究...

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教育背景

1986年6月于北京医科大学(现北京大学医学部)获学士学位,1992年6月于中国药科大学获博士学位,

工作经历

2001年至2003年在美国University Of the Pacific和Univeristy of California at San Francisco从事博士后学习和研究。

项目课题经历

近年来,主持和参与国家“十一五”“十二五”“十三五”重大新药创制科技重大专项、美国国立卫生研究院(NIH)项目、国家自然科学基金面上项目、科技部科技支撑计划等国际和国家级课题十余项。另主持企业委托课题数十项,并完成新药申报。作为中国药科大学“药用辅料及仿创药物研发评价中心”分中心负责人,近3年来,项目签约经费累计逾4000万元。

论文、成果、著作等

[1]Qiyue Wang, Gujie Mi, Daniel Hickey, Yanan Li, Jiasheng Tu*, Thomas J. Webster*, Yan Shen*. Azithromycin-loaded respirable microparticles for targeted pulmonary delivery for the treatment of pneumonia. Biomaterials (IF=8.806), 2018, 160: 107-123.

[2]Yanan Li#, Dongsheng He#, Jiasheng Tu#, Ru Wang, Chang Zu, You Chen, Wenqian Yang, Di Shi, Thomas J. Webster*, Yan Shen*. The comparative effect of wrapping solid gold nanoparticles and hollow gold nanoparticles with doxorubicin-loaded thermosensitive liposomes for cancer thermo-chemotherapy. Nanoscale (IF=7.233), 2018, 10, 8628-864.

[3]Baoqiang Tang#, Jennica L. Zaro#, Yan Shen, Qian Chen, Yinglan Yu, Pingping Sun, Yanqi Wang, Wei-Chiang Shen, Jiasheng Tu*, Chunmeng Sun*. Acid-sensitive hybrid polymeric micelles containing a reversibly activatable cell-penetrating peptide for tumor-specific cytoplasm targeting. Journal of Controlled Release (IF=7.877), 10 June 2018, 279: 147-156.

[4]Liping Huang, Birendra Chaurasiya, Dawei Wu, Huimin Wang, Yunai Du, Jiasheng Tu*, Thomas J. Webster, Chunmeng Sun*. Versatile redox-sensitive pullulan nanoparticles for enhanced liver targeting and efficient cancer therapy. Nanomedicine: Nanotechnology, Biology and Medicine (IF=6.500), April 2018, 14(3): 1005-1017.

[5]Junping Xia#, Yunai Du#, Liping Huang, Birendra Chaurasiya, Jiasheng Tu*, Thomas J. Webster, Chunmeng Sun*. Redox-responsive micelles from disulfide bond-bridged hyaluronic acid-tocopherol succinate for the treatment of melanoma. Nanomedicine: Nanotechnology, Biology and Medicine (IF=6.500), April 2018, 14(3): 713-723.

专利、著作版权等

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