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钱帅

领域:生物产业 学校:中国药科大学职称:副教授

药物制剂新剂型与新技术 中药制剂晶体学研究 中药高分子辅料研究 药物代谢动力学研究...

具体了解该专家信息,请致电:027-87555799 邮箱 haizhi@uipplus.com

教育背景

2010.01~2013.08 香港中文大学药剂学院博士

2007.09~2009.12 香港科学园CDEPharma Ltd. 制剂研究员

2004.09~2007.06 中国药科大学药学院硕士

2000.09~2004.07 中国药科大学中药学院本科

工作经历

2018.08~至今 中国药科大学中药制剂系副教授 2014.09~2018.07 中国药科大学中药制剂系讲师 2013.09~2014.08 香港中文大学药剂学院研究助理

项目课题经历

主持国家自然科学基金青年基金、江苏省自然科学基金青年基金、江苏省“双创计划”、中央高校基金项目等各类科研项目。

论文、成果、著作等

[1] Pang Z, Wei Y, Wang N, Zhang J, Gao Y, Qian S*. Gel formation of puerarin and mechanistic study during its cooling process. Int J Pharm. 2018, 548(1): 625-635.

[2] Qian S, He L, Wang Q, Wong YC, Mak M, Ho CY, Han Y, Zuo Z. Intranasal delivery of a novel acetylcholinesterase inhibitor HLS-3 for treatment of Alzheimer's disease. Life Sci. 2018, 207: 428-435.

[3] Qian S, Wang S, Li Z, Wang X, Ma D, Liang S, Gao Y, Zhang J, Wei Y. Charge-assisted bond N+-H mediates the gelation of amorphous lurasidone hydrochloride during dissolution. Int J Pharm. 2017, 518: 335-341.

[4] Hao T, Ling Y, Wu M, Shen Y, Gao Y, Liang S, Gao Y, Qian S*. Enhanced oral bioavailability of docetaxel in rats combined with myricetin: In situ and in vivo evidences. Eur J Pharm Sci. 2017, 101: 71-79.

[5] Qian S, Li Z, Heng W, Liang S, Ma D, Gao Y, Zhang J, Wei Y. Charge-assisted intermolecular hydrogen bond formed in coamorphous system is important to relieve the pH-dependent solubility behavior of lurasidone hydrochloride. RSC Adv. 2016, 6: 106396-106412.

[6] Qian S, Heng W, Wei Y, Zhang J, Gao Y. Coamorphous lurasidone hydrochloride-saccharin with charge-assisted hydrogen bonding interaction shows improved physical stability and enhanced dissolution with pH-independent solubility behavior. Cryst Growth Des. 2015, 15: 2920-2928.

[7] Qian S, He L, Mak M, Han Y, Ho CY, Zuo Z. Synthesis, biological activity, and biopharmaceutical characterization of tacrine dimers as acetylcholinesterase inhibitors. Int J Pharm. 2014, 477: 442-453.

[8] Qian S, Wang Q, Zuo Z. Improved brain uptake of peptide-based CNS drugs via alternative routes of administrations of its nanocarrier delivery systems: a promising strategy for CNS targeting delivery of peptides. Expert Opin Drug Metab Toxicol. 2014, 10: 1491-1508.

[9] Qian S, Wong YC, Zuo Z. Development, characterization and application of in situ gel systems for intranasal delivery of tacrine. Int J Pharm. 2014, 468: 272-282.

[10] Qian S, Zhang Q, Wang Y, Lee B, Betageri GV, Chow MSS, Huang M, Zuo Z. Bioavailability enhancement of glucosamine hydrochloride by chitosan. Int J Pharm. 2013, 455: 365-73.

专利、著作版权等

获授权中国专利2项,PCT国际专利2项。
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