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戚进

领域:生物产业 学校:中国药科大学职称:教授

:①基于传统功效的中药物质基础研究;②中药质量控制新方法研究...

具体了解该专家信息,请致电:027-87555799 邮箱 haizhi@uipplus.com

教育背景

2001年获得中国药科大学中药鉴定专业学士学位,2006年获中国药科大学生药学博士学位,

工作经历

2013-2014赴美国北达科他州立大学药学系进行访学(访问学者)。

项目课题经历

1. “基于“成分-靶点-效应”复合网络体系探索增液汤治疗糖尿病的物质基础和组方原理”(81673555),国家自然科学基金面上项目,57万,2017.01-2020.12,主持,进行中。

2. “基于自由基代谢建立中药心血管活性物质基础的多评价体系”(81473317),国家自然科学基金面上项目,75万,2015.01-2018.12,主持,进行中。

3. “从两类功能化合物的协同作用探讨中药玄参滋阴降火功效的物质基础”(30901956),国家自然科学基金青年项目,20万,2010.01-2012.12,主持,已完成。

论文、成果、著作等

1. Li DP, Yi RX, Tian JW, Li JH, Yu BY*, & Qi J*. Rational synthesis of hierarchical magnetic mesoporous silica microspheres for enhanced enzymes immobilization. Chemical Communications, 2017, 53 (63): 8902-8905

2. Qi J1, Sun LQ1, Qian SY*, Boyang Yu*. A novel multi-hyphenated analytical method to simultaneously determine xanthine oxidase inhibitors and superoxide anion scavengers in natural products. Analytica Chimica Acta, 2017, 984,124-133

3. Guo Y.J., Sun L.Q., Yu B.Y.*, Qi J.* An integrated antioxidant activity fingerprint for commercial teas based on their capacities to scavenge reactive oxygen species. Food Chemistry, 2017, 237(15):645-653

4. Wang L, Zhang F, Cao ZY, Xiao Y, Li SX, Yu BY⁎, Qi J⁎. Ginsenoside F2 induces the release of mediators associated with Anaphylactoid reactions. Fitoterapia, 2017, 121, 223-228

5. Wang L, Zhao YZ, Yang Y, Zou XH, Yu BY⁎, Qi J⁎. Allergens in red ginseng extract induce the release of mediators associated with anaphylactoid reactions, Journal of Translational Medicine, 2017, 15 (1):148, DOI 10.1186/s12967-017-12 49-x

6. Wang T., Li D.P., Yu B.Y.*, Qi J.*. Screening inhibitors of xanthine oxidase from natural products using enzyme immobilized magnetic beads by high-performance liquid chromatography coupled with tandem mass spectrometry. Journal of separation science, 2017, 40(9): 1877-1886

7. Wu Y., Wang X.M., Bi S.X., Zhang W., Li R.M., Wang R.J., Yu B.Y.*, Qi J.*. Novel cytotoxic steroidal saponins from the roots of Liriope muscari (Decne.) L.H. Bailey, RSC Advances, 2017, 7, 13696–13706

8. Chen XL, Qi J*, Yu BY. Quantitative analysis of salvianolic acids, ginsenosides and borneols using 1H qNMR for quality control of compound Danshen dripping pills. Analytical Methods, 2017, 9, 5580 – 5585

9. Yang Y, Tian YX, Hu SY, Bi SX, Li SX, Kou JP, Qi J*, Yu BY*. Extract of Sheng-Mai-San ameliorates myocardial ischemia induced heart failure through modulating Ca2+-calcineurin-mediated Drp1 signaling pathways, International Journal of Molecular Sciences, 2017, 18(9), 1825; doi:10.3390/ijms18091825

10. Qi J., Chen Y.H., Wang Y., Chen X., Wang L., Hu Y.J., Yu B.Y.*. Screening of peroxynitrite scavengers in Flos Lonicerae by using two new methods, an HPLC-DAD-CL technique and a peroxynitrite spiking test followed by HPLC-DAD analysis, Phytochemical Analysis, 2016, 27(1): 57–63

11.Liu C.H., Li M., Feng Y.Q., Hu Y.J., Yu B.Y.*, Qi J.*. Determination of ruscogenin in ophiopogonis radix by high-performance liquid chromatography-evaporative light scattering detector coupled with hierarchical clustering analysis, Pharmacognosy Magazine, 2016, 12(45): 13–20

12. Chen X.L., Guo Y.J., Hu Y.J., Yu B.Y.*, Qi J.*. Quantitative analysis of highly similar salvianolic acids with 1H qNMR for quality control of traditional Chinese medicinal preparation Salvianolate Lyophilized Injection, Journal of pharmaceutical and biomedical analysis, 2016, 124: 281-287

13. Guo Y.J.#, Chen X.#, Qi J*, Yu B.Y.. Simultaneous qualitative and quantitative analysis of flavonoids and alkaloids from the leaves of NelumbonuciferaGaertn. using high‐performance liquid chromatography with quadrupole time‐of‐flight mass spectrometry, Journal of Separation Science, 2016, 39(13):2499-2507

14. Yang J., Hu Y.J., Yu B.Y.*, Qi J.*. Integrating qualitative and quantitative characterization of Prunellae Spica by HPLC-QTOF/MS and HPLC-ELSD, Chinese Journal of Natural Medicines, 2016, 14(5): 391-400

15. Feng Y.Q., Ju A.C., Liu C.H., Wang T., Yu B.Y.*, Qi J.*. Protective effect of the extract of Yi-Qi-Fu-Mai preparation on hypoxia-induced heart injury in mice, Chinese Journal of Natural Medicines, 2016, 14(6): 401-406.

16. Liu C.H. #, Ju A.C.#, Zhou D.Z., Li D.K., Kou J.P., Yu B.Y.*, Qi J.*. Simultaneous Qualitative and Quantitative Analysis of Multiple Chemical Constituents in YiQiFuMai Injection by Ultra-Fast Liquid Chromatography Coupled with Ion Trap Time-of-Flight Mass Spectrometry, Molecules, 2016, 21(5):640.

17. Chen H.F., Chen Y.H., Liu C.H., Wang L., Chen X., Yu B.Y.*, Qi J.*. Integrated chemometric fngerprints of antioxidant activities and HPLC–DAD–CL for assessing the quality of the processed roots of Polygonum multiflorum Thunb. (Heshouwu), Chinese medicine, 2016, 11(18):1-124.

18. Li D.P., Wang T., Guo Y.J., Hu Y.J., Yu B.Y.*, Qi J.*.Online screening of nitric oxide scavengers in natural products using high performance liquid chromatography coupled with tandem diode arrayand fluorescence detection, Journal of Chromatography A, 2015, 1425, 106-115

19. Ding F., Zhang Q.R., Ung C. O. L., Wang Y., Han Y., Hu Y.J., & Qi J.*. An Analysis of Chemical Ingredients Network of Chinese Herbal Formulae for the Treatment of Coronary Heart Disease. PloS one, 2015, 10(2), e0116441

20. Qi J. #, Hu Z.F. #, Zhou Y.F., Hu Y.J. & Yu B.Y.*. Steroidal Sapogenins and Glycosides from the Fibrous Roots of Ophiopogon japonicus and Liriope spicata var. prolifera with Anti-inflammatory Activity. Chemical and Pharmaceutical Bulletin, 2015, 63(3), 187-194.

21.Wang H.#, Qi J.#, Han D.Q., Xu T., Liu J.H., Qin M.J., Zhu D.N. & Yu B.Y*. Cause and control of Radix Ophiopogonis browning during storage. Chinese journal of natural medicines, 2015, 13(1), 73-80.

专利、著作版权等

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