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柳文媛

领域:生物产业 学校:中国药科大学职称:教授

从事药物仪器分析研究...

具体了解该专家信息,请致电:027-87555799 邮箱 haizhi@uipplus.com

教育背景

1996年获中国药科大学药物分析硕士学位并留校任教至今;2004年获本校药物分析博士学位;

工作经历

2008年4~10月美国University of California, San Diego访问学者;2016年5月起任药物分析系主任

项目课题经历

论文、成果、著作等

. Rapid and simultaneous determination of sulfonate ester genotoxic impurities in drug substance by liquid chromatography coupled to tandem mass spectrometry: comparison of different ionisation modes, Journal of Chromatography A,2014, 1355, 73-79. (IF 4.25)

2. Determination of small halogenated carboxylic acid residues in drug substances by high performance liquid chromatography-diode array detection following derivatization with nitro-substituted phenylhydrazines, Journal of Chromatography A, 2016, 1428, 46-56. (IF 3.923)

3. Development and validation of a general derivatization HPLC method for the trace analysis of acyl chlorides in lipophilic drug substances. Journal of Pharmaceutical and Biomedical Analysis, 2017, 140, 327-333. (IF 3.255)

4. Metabolic profile of 5-hydroxy-4-methoxycanthin-6-one, a typical canthinone alkaloid, in rats determined by liquid chromatography-quadrupole time-of-flight tandem mass spectrometry together with multiple data processing techniques. Journal of Pharmaceutical and Biomedical Analysis, 2016, 129, 60-69. (IF 3.169)

5. Chotosan improves Aβ1-42-induced cognitive impairment and neuroinflammatory and apoptotic responses through the inhibition of TLR-4/NF-κB signaling in mice.Journal of ethnophamacology, 2016, 191,398-407. (IF 3.055)

专利、著作版权等

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