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李玉艳

领域:生物产业 学校:中国药科大学职称:副教授

研究方向为新药分子设计与合成,药物合成工艺革新和产业化...

具体了解该专家信息,请致电:027-87555799 邮箱 haizhi@uipplus.com

教育背景

工作经历

项目课题经历

主持国家自然科学基金1项,江苏省自然科学基金2项,江苏省产学研前瞻性项目1项,企业合作项目1项;参与国家自然科学基金重点项目,国家自然科学基金,国家重大新药创制科技重大专项等多项

论文、成果、著作等

1, Tuning Stereo-hindrance of Curcumin Scaffold for Selective Imaging of Soluble Forms of Amyloid Beta Species,Yuyan Li, Jian Yang, Hongwu Liu, Jing Yang, Lei Du, Haiwei Feng, Yanli Tian, Jianqin Cao and Chongzhao Ran*,Chemical Science, 2017, 8, 7710 – 7717. (IF8.668)

2,Ying Ge, Aibo Li, Jianwei Wu, Haiwei Feng , Letian Wang , Hongwu Liu ,Yungen Xu, Qingxiang Xu ***, Li Zhao **, Yuyan Li *, Design, synthesis and biological evaluation of novel non-peptide boronic acid derivatives as proteasome inhibitors, European Journal of Medicinal Chemistry, 2017, 128: 180-191. (IF 4.52)

3, Hongwu Liu, Jian Yang, Letian Wang, Yungen Xu, Siyuan Zhang, Jie Lv, Chongzhao Ran, Yuyan Li*, Targeting β-amyloid plaques and oligomers: development of near-IR fluorescence imaging probes,Future Medicinal Chemistry, 2017 , 9(2), 179-198. (IF 3.58)

4, Aibo Li,Haopeng Sun,Lei Du,Xiaoxin Wu,Jianqin Cao,Qidong You,Yuyan Li*,Discovery of novelcovalent proteasome inhibitors through a combination of pharmacophore screening, covalent docking, andmolecular dynamics simulations[J],Journal of Molecular Modeling,2014,20:2515。(IF 1.98)

5, Yanli Tian,Xueli Zhang,Yuyan Li,Timothy M. Shoup,Xin Teng,David R. Elmaleh,Anna Moore*,Chongzhao Ran*,Crown ethers attenuate aggregation of Amyloid beta of Alzheimer’sdisease,Chem.Comm.,2014,50(99):15792-15795。(IF6.38)

6, Ye-Xiang Su, Ya-Hui Deng, Ting-Ting Ma, Yu-Yan Li* and Li-Ping Sun*.“On water”direct Pd-catalysed C–H arylation of thiazolo[5,4-d]pyrimidine derivatives[J]. Green Chem., 2012, 14, 1979(IF 6.32)

专利、著作版权等

主持国家自然科学基金1项,江苏省自然科学基金2项,江苏省产学研前瞻性项目1项,企业合作项目1项;参与国家自然科学基金重点项目,国家自然科学基金,国家重大新药创制科技重大专项等多项
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