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李彬

领域:生物产业 学校:中国药科大学职称:教授

MALDI质谱成像新技术、新方法的研究与应用 2.基于生物质谱技术的时空代谢组学研究 3.面向中药复杂体系的质谱成像关键技术研究...

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教育背景

本科、硕士毕业于中国药科大学,博士毕业于丹麦哥本哈根大学生物分析化学专业

工作经历

随后加入美国伊利诺伊大学厄巴纳-香槟分校化学系从事博士后研究工作。

项目课题经历


国家自然科学基金委面上项目:集成多元质谱成像技术研究舒肝解郁胶囊改善卒中后抑郁多系统器官代谢紊乱的作用(主持)


2.国家自然科学基金委面上项目:基于质谱成像技术的远志干预阿尔茨海默病的组织特异性分布—脑代谢调控研究(主持)

论文、成果、著作等


Li, B.*,#; Sun, R.#; Gordon, A.; Ge, J.; Zhang, Y.; Li, P.*; Yang, H.*, 3-Aminophthalhydrazide (Luminol) As a Matrix for Dual-Polarity MALDI MS Imaging. Anal Chem 2019, 91 (13), 8221-8228.


2.Tang, W. W.#; Chen, J.#; Zhou, J.; Ge, J. Y.; Zhang, Y.; Li, P.*; Li, B.*, Quantitative MALDI Imaging of Spatial Distributions and Dynamic Changes of Tetrandrine in Multiple Organs of Rats. Theranostics2019, 9 (4), 932-944. 封面文章


3.Li, B.; Neumann, E. K.; Ge, J. Y.; Gao, W.; Yang, H.; Li, P.*; Sweedler, J. V.*, Interrogation of spatial metabolome of Ginkgo biloba with high-resolution matrix-assisted laser desorption/ionization and laser desorption/ionization mass spectrometry imaging. Plant Cell Environ2018, 41 (11), 2693-2703. 封面文章


4.Li, B.#; Dunham, S. J. B.#; Ellis, J. F.#; Lange, J. D.; Smith, J. R.; Yang, N.; King, T. L.; Amaya, K. R.; Arnett, C. M.*; Sweedler, J. V.*, A Versatile Strategy for Characterization and Imaging of Drip Flow Microbial Biofilms. Anal Chem2018, 90 (11), 6725-6734.


5.Si, T.#; Li, B.#; Comi, T. J.; Wu, Y. W.; Hu, P. F.; Wu, Y. Y.; Min, Y. H.; Mitchell, D. A.; Zhao, H. M.*; Sweedler, J. V.*, Profiling of Microbial Colonies for High-Throughput Engineering of Multistep Enzymatic Reactions via Optically Guided Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry. J Am Chem Soc2017, 139 (36), 12466-12473.


6.Li, B.; Dunham, S. J. B.; Dong, Y. H.; Yoon, S.; Zeng, M. M.; Sweedler, J. V.*, Analytical capabilities of mass spectrometry imaging and its potential applications in food science. Trends Food Sci Tech2016, 47, 50-63.


7.Li, B.#; Bhandari, D. R.#; Janfelt, C.; Rompp, A.; Spengler, B.*, Natural products in Glycyrrhiza glabra (licorice) rhizome imaged at the cellular level by atmospheric pressure matrix-assisted laser desorption/ionization tandem mass spectrometry imaging. Plant J2014, 80 (1), 161-171.


8.Li, B.; Knudsen, C.; Hansen, N. K.; Jorgensen, K.; Kannangara, R.; Bak, S.; Takos, A.; Rook, F.; Hansen, S. H.; Moller, B. L.; Janfelt, C.*; Bjarnholt, N.*, Visualizing metabolite distribution and enzymatic conversion in plant tissues by desorption electrospray ionization mass spectrometry imaging. Plant J2013, 74 (6), 1059-1071.

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