1994.6毕业于中国药科大学中药药理专业，留校在中药学院中药复方研究室工作，主要从事中药复方药效物质基础与作用机理研究；2000.6/2005.6，师从严永清教授在职攻读本校中药学硕士学位，2001.9-2005.6，师从徐强教授在职攻读南京大学生理学专业博士学位

2007.10-2008.10, 日本岐阜药科大学访问学者；2009.6 破格晋升教授。

先后主持国家自然科学基金青年基金（麦冬皂苷防治静脉血栓的抗粘附机制研究）、面上项目（从1型组胺受体途径探索当归芍药散异病同治原理研究、基于NMMHCⅡA-TF信号通路探讨麦冬皂苷防治血栓性疾病的新机制、生脉散有效成分群调控AMPK/NMMHCIIA/14-3-3 防治心肌缺血再灌注损伤多靶点整合机制研究），国家十一五科技支撑计划（以定向吸附技术为先导探索中药有效成分作用靶点的方法），新世纪优秀人才支持计划（鲁斯可皂苷元的功能靶标发现和相关信号转导通路研究）等10余项国家省部级课题；主持完成企业委托课题十余项（在注射用益气复脉（冻干）发挥疗效中的效应物质及其作用特点研究、丹参口服液的药效毒理等）；作为项目副组长承担2项国家科技部重大新药创制科技专项，主要参与完成“863”项目、国家自然科学科学基金重大研究计划、教育部重点课题、江苏省自然科学基金、企业委托课题等研究项目20余项。

1)YiQiFuMai Powder Injection ameliorates the oxygen-glucose deprivation-induced brain microvascular endothelial barrier dysfunction associated with the NF-κB and ROCK1/MLC signaling pathways. J Ethnopharmacol, 2016,183:18-28.
2)YiQiFuMai Powder Injection ameliorates cerebral ischemia by inhibiting endoplasmic reticulum stress-mediated neuronal apoptosis. Oxid Med Cell Longev, 2016, 2016:5493279 doi:10.1155/2016/5493279.
3)Diosgenin regulates adipokine expression in perivascular adipose tissue and ameliorates endothelial dysfunction via regulation of AMPK. J Steroid Biochem Mol Biol, 2016, 155:155-165.
4)Non-muscle myosin heavy chain IIA inhibition impedes tissue factor expression and venous thrombosis via Akt/GSK3β-NF-κB signaling pathways in the endothelium. Thromb Haemostasis, 2015,114(1):173-185.
5)The saponin DT-13 attenuates tumor necrosis factor-a-induced vascular inflammation associated with Src/NF-kB/MAPK pathway modulation. Int J Biol Sci, 2015,11(8):970-981.
6)Cocktail of four active components derived from Sheng-mai San inhibits hydrogen peroxide induced PC12 cell apoptosis linked with caspase-3/ROCK1/MLC pathway. Rejuv Res, 2015, 18(6):517-527.
7)An integrated pathway interaction network for the combination of four effective compounds from ShengMai preparations in the treatment of cardio-cerebral ischemic diseases. Acta Pharmacol Sin, 2015, 36(11):1337-1348.
8)A combination of four active compounds alleviates cerebral ischemia-reperfusion injury in correlation with inhibition of autophagy and modulation of AMPK/mTOR and JNK pathways. J Neurosci Res, 2014, 92(10):1295-306.
9)Diosgenin ameliorates palmitate-induced endothelial dysfunction and insulin resistance via blocking IKKb and IRS-1 pathways. Atherosclerosis, 2012, 223(2): 350-358.
10)Ginsenoside Rg1 protects against hydrogen peroxide-induced cell death in PC12 cells via inhibiting NF-kB activation. Neurochem Int, 2011, 58(1):119-125.

获专利证书17项