糜岚——海智汇

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糜岚

领域：新一代信息技术产业学校：复旦大学职称：副教授

光学在生物医学上的应用
1. 基于共焦显微镜系统的单光子、双光子荧光显微的活体生物成像以及相关的物理问题 2. 光谱分辨和时间分辨的荧光检测在生物中的应用 3. 癌症的早期诊断和光动力治疗 4. 光学探针、纳米荧光颗粒和生物靶向性纳米材料在生物医学研究中的应用
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专家简介

教育背景

2002.9至2007.6 复旦大学信息学院光科学与工程系理学博士
2001.6 至2001.8 台湾新竹清华大学物理系两岸交流“莙政学者”
1998.9至2002.6 复旦大学物理系理学学士
2003.8至2004.8 美国东密歇根大学(Eastern Michigan Univ.)物理系访问学者

工作经历

项目课题经历

论文、成果、著作等

X. Pan, X. Liang, L. Yao, X. Wang, Y. Jing, J. Ma, Y. Fei, L. Chen, L. Mi*, “Study of the Photodynamic Activity of N-Doped TiO₂ Nanoparticles Conjugated with Aluminum Phthalocyanine”, Nanomaterials, 7, 338 (2017).
M. Wang, F. Tang, X. Pan, L. Yao, X. Wang, Y. Jing, J. Ma, G.g Wang, L. Mi*, "Rapid Diagnosis and Intraoperative Margin Assessment of Human Lung Cancer with Fluorescence Lifetime Imaging Microscopy", BBA Clinical, 8, 7-13 (2017)
M. Wang, F. Long, F. Tang, Y. Jing, X. Wang, L. Yao, J. Ma, Y. Fei, L. Chen, G. Wang, L. Mi*,"Autofluorescence Imaging and Spectroscopy of Human Lung Cancer", Appl. Sci. 7 (2017) 32.
J. Xie, X. Pan, M. Wang, J. Ma, Y. Fei, P.-N. Wang, L. Mi*,"The role of surface modification for TiO₂ nanoparticles in cancer cells", Colloid. Surface. B 143 (2016) 148.
Y. Wang, C. Song, M. Wang, Y. Xie, L. Mi*, G. Wang,"Rapid, Label-Free, and Highly Sensitive Detection of Cervical Cancer With Fluorescence Lifetime Imaging Microscopy", IEEE J. Sel. Top. Quant. 22 (2016) 6801307.
J. Xie, X. Pan, M. Wang, L. Yao, X. Liang, J. Ma, Y. Fei, P.-N. Wang, L. Mi*,"Targeting and Photodynamic Killing of Cancer Cell by Nitrogen-Doped Titanium Dioxide Coupled with Folic Acid", Nanomaterials 6 (2016) 113.
X. Pan, J. Xie, Z. Li, M. Chen, M. Wang, P.-N. Wang, L. Chen, L. Mi*,"Enhancement of the photokilling effect of aluminum phthalocyanine in photodynamic therapy by conjugating with nitrogen-doped TiO₂ nanoparticles", Colloid. Surface. B 130 (2015) 292.
L. Mi, A. Goryaynov, A. Lindquist, M. Rexach, W. Yang,"Quantifying Nucleoporin Stoichiometry Inside Single Nuclear Pore Complexes In vivo", Sci. Rep. 5 (2015) 9372.
X. Pan, Z. Li, T. Wang, J. Xie, P.-N. Wang, J.-Y. Chen, L. Chen, L. Mi*,"Study of Polycation-Capped Mn:ZnSe Quantum Dots as a Novel Fluorescent Probe for Living Cells", J. Fluoresc. 24 (2014) 767.
Z. Li, X. Pan, T. Wang, P.-N. Wang, J.-Y. Chen, L. Mi*,"Comparison of the killing effects between nitrogen-doped and pure TiO₂ on HeLa cells with visible light irradiation", Nanoscale Res. Lett. 8 (2013) 96.
Z. Li, L. Mi*, P.-N. Wang, J.-Y. Chen,"Study on the visible-light-induced photokilling effect of nitrogen-doped TiO₂ nanoparticles on cancer cells", Nanoscale Res. Lett. 6 (2011)
R. Xiong, Z. Li, L. Mi*, P.-N. Wang, J.-Y. Chen, L. Wang, W.-L. Yang,"Study on the Intracellular Fate of Tat Peptide-Conjugated Quantum Dots by Spectroscopic Investigation", J. Fluoresc. 20 (2010) 551.
L. Mi, R. Xiong, Y. Zhang, Z. Li, W. Yang, J.-Y. Chen, P.-N. Wang,"Microscopic observation of the intercellular transport of CdTe quantum dots through tunneling-nanotubes", J. Biomaterials Nanobiotech. 2 (2011) 172.
L. Mi, Y. Zhang, P.-N. Wang,"First-principles study of the hydrogen doping influence on the geometric and electronic structures of N-doped TiO₂", Chem. Phys. Lett. 458 (2008) 341.
L. Mi, P. Xu, P.-N. Wang,"Experimental study on the bandgap narrowings of TiO₂ films calcined under N₂ or NH₃ atmosphere", Appl. Surf. Sci. 255 (2008) 2574.
L. Mi, P. Xu, H. Shen, P.-N. Wang,"Recovery of visible-light photocatalytic efficiency of N-doped TiO₂ nanoparticulate films", J. Photoch. Photobio. A 193 (2008) 222.
L. Mi, P. Xu, H. Shen, P.-N. Wang, W. Shen,"First-principles calculation of N : H codoping effect on energy gap narrowing of TiO₂", Appl. Phys. Lett. 90 (2007)
L. Mi, H. Ling, W. Shen,"Some complementary scratch resistance characterization methods", JCT Research 3 (2006) 249.
L. Mi, P. Xu, P.-N. Wang,"Temperature determination of N₂ discharge plasma by computational simulation of its emission spectra", J. Phys. D 38 (2005) 3885.
C. Zhu, X. Zhu, J. P. Landry, Z. Cui, Q. Li, Y. Dang, L. Mi, F. Zheng, Y. Fei,"Developing an Efficient and General Strategy for Immobilization of Small Molecules onto Microarrays Using Isocyanate Chemistry", Sensors 16 (2016) 378.
C. Zhu, R. Chen, Y. Zhu, X. Wang, X. Zhu, L. Mi, F. Zheng, Y. Fei,"Calibration of oblique-incidence reflectivity difference for label-free detection of a molecular layer", Appl. Opt. 55 (2016) 9459.
H. Meng, J.-Y. Chen, L. Mi, P.-N. Wang, M.-Y. Ge, Y. Yue, N. Dai,"Conjugates of folic acids with BSA-coated quantum dots for cancer cell targeting and imaging by single-photon and two-photon excitation", J. Biol. Inorg. Chem. 16 (2011) 117.
Y. Zhang, L. Mi, J.-Y. Chen, P.-N. Wang,"The environmental influence on the photoluminescence behavior of thiol-capped CdTe quantum dots in living cells", Biomed. Mater. 4 (2009)

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