领域：生物产业 学校：复旦大学职称：副研究员
以酵母为模式生物，利用表观遗传，分子遗传和生物化学等手段，研究表观遗传调控在维持基因组稳定性中的作用。
Using yeast as model organism, study the regulation of genomic stability, by epigenetic, molecular genetic and biochemical approaches.
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具体了解该专家信息，请致电：027-87555799 邮箱 haizhi@uipplus.com
1. Yu, Y*†., Zhou, H†., Deng, X., Wang, W. & Lu, H. (2016) Set3 contributes to heterochromatin integrity by promoting transcription of subunits of Clr4-Rik1-Cul4 histone methyltransferase complex in fission yeast, Sci Rep. 6, 31752.
2. Zhou, H., Liu, Q., Shi, T., Yu, Y*. & Lu, H. (2015) Genome-wide screen of fission yeast mutants for sensitivity to 6-azauracil, an inhibitor of transcriptional elongation, Yeast. 32, 643-55.
3. Deng, X., Zhou, H., Zhang, G., Wang, W., Mao, L., Zhou, X., Yu, Y#. & Lu, H#. (2015) Sgf73, a subunit of SAGA complex, is required for the assembly of RITS complex in fission yeast, Sci Rep. 5, 14707.
4. Lei, B†.., Zhou, N†.., Guo, Y., Zhao, W., Tan, Y. W., Yu, Y#. & Lu, H#. (2014) Septin ring assembly is regulated by Spt20, a structural subunit of the SAGA complex, J Cell Sci. 127, 4024-36.
5. Pan, X†., Lei, B†., Zhou, N., Feng, B., Yao, W., Zhao, X., Yu, Y#. & Lu, H#. (2012) Identification of novel genes involved in DNA damage response by screening a genome-wide Schizosaccharomyces pombe deletion library, BMC Genomics. 13, 662.
6. Li, Y†., Yu, Y†., Zhang, Y†., Zhou, Y., Li, C., Zhu, J., Yuan, H. & Lu, H*. (2011) MAFIP is a tumor suppressor in cervical cancer that inhibits activation of the nuclear factor-kappa B pathway, Cancer Sci. 102, 2043-50.
7. Yu, Y., Srinivasan, M., Nakanishi, S., Leatherwood, J., Shilatifard, A. & Sternglanz, R*. (2011) A conserved patch near the C terminus of histone H4 is required for genome stability in budding yeast, Mol Cell Biol. 31, 2311-25.
8. Kumar, P. R., Yu, Y., Sternglanz, R., Johnston, S. A. & Joshua-Tor, L*. (2008) NADP regulates the yeast GAL induction system, Science. 319, 1090-2.
