领域:生物产业 学校:复旦大学职称:副教授
分子免疫学,感染与免疫,肿瘤分子生物学DNA-seq、RNA-seq和iTRAQ等DNA,RNA和蛋白质大数据分析
1.通过芯片和数学模型等分析细胞分子互作网络以及调控网络。2.通过进化分析,meta-analysis, 生物统计学分析,结构模拟和分析动力学等生物信息学手段分析蛋白和DNA的功能。3.使用lotusScript,Visual C#, Perl, 和MySQL 设计生物学程序和专业数据库。
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具体了解该专家信息,请致电:027-87555799 邮箱 haizhi@uipplus.com
1. Wang J,Su C, Liu R,Liu B,Khan IU, Xie J* Zhu N*, Systems Pharmacology-based strategy to screen adjuvant from Traditional Chinese Medicine Ophiocordyceps sinensis Science Report 2017 DOI: 10.1038/srep44788 (accepted, )
2. Wang J,Su C, Liu R,Liu B,Khan IU, Xie J* Zhu N*, A Pre-Clinical Safety Evaluation of SBP (HBsAg-Binding Protein) Adjuvant for Hepatitis B Vaccine, PLoS One. 2017,12(1), DOI:10.1371/journal.pone.0170313.
3. Inam UK, Huang JS, Liu R, Wang JB, Xie J*, Zhu NS*, Phage Display–Derived Ligand for Mucosal Transcytotic Receptor GP-2 Promotes Antigen Delivery to M Cells and Induces Antigen-Specific Immune Response, SLAS Discovery, 2017: 1-8 DOI:10.1177/24725552472555217690483 (press online: http://journals.sagepub.com/doi/full/10.1177/2472555217690483)
4. Tang LS, Zhu HR, Yang XM, Xie F, Peng JT, Jiang DK*, Xie J*, Qi YM*,and Yu L. Shizukaol D, a Dimeric Sesquiterpene Isolated from Chloranthus Serratus, Represses the Growth of Human Liver Cancer Cells by Modulating Wnt Signalling Pathway,PLoS One. 2016,11(3)
5. Deng HY(#),Xie J(#),Chen JQ,Xie H,Gu Y(#),Yuan K,Wang P,Shen W,Liang W,Zhang H, Zhang JW,Zhang L(*), Rare double heterozygous mutations in antithrombin underlie hereditary thrombophilia in a Chinese family,Journal of Thrombosis and Thrombolysis,2013,36(3):300-306
6. Xie J,Zhang M,Zhou T, Hua X,Tang LS and Wu WL,Sno/scaRNAbase: a curated database for small nucleolar RNAs and small cajar body-specific RNAs,Nucl. Acids. Res. 2017,35,D183-187.