领域：生物产业 学校：复旦大学职称：副教授
复杂性状（疾病）的遗传学机制，包括: （1）以酵母为模式研究细胞的乙醇耐受性、细胞粘附性以及转录调控等复杂遗传变异的分子学机制；（2） 基于转录组、miRNA组、外显子组及甲基化组等的新一代测序数据，寻找和发掘导致非小细胞肺癌发生、发展的遗传变异体，并致力于揭示其分子机理。
...
具体了解该专家信息，请致电：027-87555799 邮箱 haizhi@uipplus.com
1. X Wu, T Liu, O Fang, LJ Leach, X Hu#, Z Luo#. (2013) miR-194 suppresses metastasis of non-small cell lung cancerthrough regulating expression of BMP1 and p27kip1. Oncogene doi:10.1038/onc.2013.108. [Epub ahead of print]
2. J Li, L Wang, X Wu, O Fang, L Wang, C Lu, S Yang, X Hu#, Z Luo#. (2013) Polygenic Molecular Architecture Underlying Non-Sexual Cell Aggregation in Budding Yeast. DNA Res 20:55-66.
3. C Lu*，X Hu*，G Wang，LJ Leach， et al. (2010) Why do essential proteins tend to be clustered in the yeast interactome network? Mol Biosyst 6:871-877.
4. M Wang*, X Hu*, Li G, Leach LJ, Potokina E, et al. (2009) Robust Detection and Genotyping of Single Feature Polymorphisms from Gene Expression Data. PLoS Comput Biol 5(3): e1000317.
5. X Hu, M Wang，T Tan, J Li, H Yang, L Leach, R Zhang, Z Luo. (2007). Genetic dissection of ethanol tolerance in budding yeast S. cerevisiae. Genetics 175(3): 1479-1487.
