领域:生物产业 学校:复旦大学职称:教授
用分子药剂学、药代动力学、药物分析学、药用材料学等手段,研究改善蛋白质与多肽、核酸、抗肿瘤药物及难溶性药物等功效的新型载体的加工、改性、组装、体内外作用机理及其给药系统的设计。
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1. Chunbai He, Yiping Hu, Lichen Yin, Cui Tang, Chunhua Yin* (2010). Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles. Biomaterials, 31(13):3657-3666.
2. Lichen Yin, Jieying Ding, Jing Zhang, Chunbai He, Cui Tang, Chunhua Yin* (2010). Polymer integrity related absorption mechanism of superporous hydrogel containing interpenetrating polymer networks for oral delivery of insulin. Biomaterials, 31(12):3347-3356.
3. Lichen Yin, Jieying Ding, Chunbai He, Liming Cui, Cui Tang*, Chunhua Yin* (2009). Drug permeability and mucoadhesion properties of thiolated trimethyl chitosan nanoparticles in oral insulin delivery. Biomaterials, 30(29):5691-5700.
4. Lichen Yin, Likun Fei, Fuying Cui, Cui Tang*, Chunhua Yin* (2007). Superporous hydrogels containing poly(acrylic acid-co-acrylamide)/ O-carboxymethyl chitosan interpenetrating polymer networks. Biomaterials, 28:1258-1266.
5. Xin Zhao, Lichen Yin, Jieying Ding, Cui Tang, Shaohua Gu, Chunhua Yin*, Yumin Mao(2010). Thiolated trimethyl chitosan nanocomplexes as gene carriers with high in vitro and in vivo transfection efficiency. J. Control Release, 144:46-54
6. Ziming Zhao, Miao He, Lichen Yin, Jiamin Bao, Lili Shi, Bingqing Wang, Cui Tang, Chunhua Yin* (2009). Biodegradable nanoparticles based on linoleic acid and poly(β-malic acid) double grafted chitosan derivatives as carriers of anticancer drugs. Biomacromolecules, 10:565-572.