领域：生物产业 学校：复旦大学职称：教授
运用膜片箝电流记录与分子生物学、免疫组化等技术结合方法,利用不同特征的神经元和非神经细胞模型研究细胞膜受体、细胞膜离子通道与细胞发育成熟、凋亡和迁移等过程中的作用以及涉及到的有关信号通路。此外，还进行抗抑郁症药物、非固醇类消炎药等的神经药理学研究。
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具体了解该专家信息，请致电：027-87555799 邮箱 haizhi@uipplus.com
1. He YL, Liu DD, Fang YJ, Zhan XQ, Yao JJ, Mei YA. Exposure to Extremely Low-Frequency Electromagnetic Fields Modulates Na(+) Currents in Rat Cerebellar Granule Cells through Increase of AA/PGE(2) and EP Receptor-Mediated cAMP/PKA Pathway. PLoS One. 2013;8 (1):e54376.
2. Yao JJ, Gao XF, Chow CW, Zhan XQ, Hu CL, Mei YA. Neuritin activates insulin receptor pathway to upregulate Kv4.2-mediated transient outward K+ current in rat cerebellar granule neurons. J. Biol. Chem. 2012；287, 41534–41545.
3. Zhou MH, Yang G, Jiao S, Hu CL, Mei YA. Cholesterol enhances neuron susceptibility to apoptotic stimuli via cAMP/PKA/CREB-dependent up-regulation of Kv2.1. J Neurochem. 2012 Feb; 120 (4):502-14. J Cell Physiol. 2012 Jan; 227(1):297-307.
4. Zhuang JL, Wang CY, Zhou MH, Duan KZ, Mei YA. TGF-β1 enhances Kv2.1 potassium channel protein expression and promotes maturation of cerebellar granule neurons. Biochem J. 2011, 438:203-15.
5. Fang YJ, Zhou MH, Gao XF, Gu H, Mei YA. Arachidonic acid modulates Na+ currents by non-metabolic and metabolic pathways in rat cerebellar granule cells.
