领域:生物产业 学校:复旦大学职称:研究员
细胞膜离子通道结构与功能,以及离子通道异常引起的相关疾病的研究:
(1)细胞膜离子通道对醛固酮分泌及血压的调控;
(2)离子通道对神经细胞凋亡及神经损伤修复调控的研究。Structure and function of ion channels, and human diseases associated with defects in ion channels.
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具体了解该专家信息,请致电:027-87555799 邮箱 haizhi@uipplus.com
1. Tian Y, Yang T, Yu S, Liu C, He M, Hu C *.Prostaglandin E2 increases migration and proliferation of human glioblastoma cells by activating transient receptor potential melastatin 7 channels. J Cell Mol Med. 2018;22(12):6327-6337.
2. Yang T, He M, Hu C *.Regulation of aldosterone production by ion channels: From basal secretion to primary aldosteronism. Biochim Biophys Acta Mol Basis Dis. 2018;1864(3):871-881.
3. Yang, Tingting ,Zhang, Hai-Liang,Liang, Qingnan,Shi, Yingtang,Mei, Yan-Ai,Barrett, Paula Q,Hu C *. Small-Conductance Ca2+-Activated Potassium Channels Negatively Regulate Aldosterone Secretion in Human Adrenocortical Cells. Hypertension,2016,68(3):785~7953.
4. Yujie , Cui,Xiaoyu , Liu,Tingting, Yang,Yan-Ai, Mei,Hu C *. Exposure to extremely low-frequency electromagnetic fields inhibits T-type calcium channels via AA/LTE4 signaling pathway. Cell Calcium,2014,55(1):48~58.
5. Hu C, Rusin CG, Tan Z , Guagliardo NA and Barrett PQ. Zona glomerulosa cells of the mouse adrenal cortex are intrinsic electrical oscillators. Journal of Clinical Investigation, 2012 ,122(6):2046-53.
6. Hu C, Depuy SD, Yao J, McIntire WE, Barrett PQ. Protein kinase A activity controls the regulation of T-type CaV3.2 channels by Gbetagamma dimers. J Biol Chem. 2009 20;284(12):7465-73..
7. Hu C, Zheng Liu, Zhe-yu Gao, Zhi-Hong Zhang and Yan-Ai Mei. 2- Iodomelatonin prevents apoptosis of cerebellar granule neurons via inhibition of A-type transient outward K+ currents. Journal of Pineal Research. 2005, 38(1):53-61.