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孔庆然

领域:生物产业 学校:东北农业大学职称:副教授

1、体细胞重编程机制; 母源小RNA功能。...

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教育背景

2008年9月——2010年6月:东北农业大学生命科学学院,生物化学与分子生物学专业,理学博士学位。 2006年9月——2008年6月:东北农业大学生命科学学院,发育生物学专业,理学硕士学位。 2002年9月——2006年6月:东北农业大学生命科学学院,生物科学专业,理学学士学位。

工作经历

2012.9至今 东北农业大学生命科学院 副教授 硕导 2010.7至2012.8 东北农业大学生命科学院 讲师

项目课题经历

论文、成果、著作等

1.Qingran Kong, Tang Hai, Yanshuang Mu, Jing Ma, Tianqing Huang, Qi Zhou, Zhonghua Liu, et al. 2014. Rosa26 locus supports tissue-specific promoter driving transgene expression specifically in pig. PLoS One. 9(9): e107945. 2.Jingyu Li, Yanjun Huan, Bingteng Xie, Qingran Kong*, Zhonghua Liu*, et al. 2014. Identification and characterization of an oocyte factor required for sperm nucleus decondensation in pig. Reproduction 148: 1-10. (corresponding author) 3.ZHOU Yang, ZHU Jiang, JIAO Mingxia, WANG Jiaqiang, KONG Qingran. 2014. The cloning and imprinting analysis of Slc22a18 and Slc22a3 in swine. Acta Veterinaria et Zootechnica Sinica. 45(10): 1600-1607. (corresponding author) 4.Qingran Kong, Bingteng Xie, Jingyu Li, Yanjun Huan, et al. 2014. Identification and characterization of an oocyte factor required for porcine nuclear reprogramming. JBC. 289(10):6960-8. 5.Qingran Kong, Guangzhen Ji, Bingteng Xie, Jingyu Li, et al. 2014. Telomere elongation facilitated by Trichostatin A in cloned embryos and pigs by somatic cell nuclear transfer. Stem cell review and report. 10(3):399-407. 6.Wenteng He*, Qingran Kong*, Yongqian Shi, Bingteng Xie, et al. 2013. Generation and Developmental Characteristics of Porcine Tetraploid Embryos and Tetraploid/diploid Chimeric Embryos. Genomics, Proteomics & Bioinformatics. 11(5): 327-33. (*equal contribution) 7.ZHOU Yang, ZHU Jiang, JIAO Mingxia, WANG Jiaqiang, KONG Qingran. 2013. Cloning and Imprinting Analysis of Asb4 and Grb10 in swine. China Animal Husbandry & Veterinary Medicine. 40(8): 61-67. (corresponding author) 8.Z. Yin*, Q.R. Kong*, Z.P. Zhao, et al. 2012. Position effect variegation and epigenetic modification of a transgene in a pig model. Genetics and Molecular Research. 11: 355-369. (*equal contribution) 9.Kui HU*, Qingran KONG*, Zeping ZHAO, et al. 2012. Assessment of Reproduction and Growth Performance of offspring derived from somatic cell cloned pigs. Animal Science Journal. 83: 639-643. (*equal contribution) 10.Q. R. KONG, M. L. WU, L. ZHANG, et al. 2011. Transgene insertion affects transcription and epigenetic modification of flanking host sequence in transgenic pigs. Cellular and Molecular Biology. 57: 1505-1512. 11.Qingran Kong, Meiling Wu, Zhenkun Wang, et al. 2011. Effect of Trichostatin A and 5-Aza-2'-deoxycytidine on transgene reactivation and epigenetic modification in transgenic pig fibroblast cells. Molecular and Cellular Biochemistry. 355: 157-165. 12.Qingran Kong, Jiang Zhu, et al. 2011. TSA improve transgenic porcine cloned embryo development and transgene expression. Hereditas. 33(7): 749-756. 13.Qingran Kong, Zhonghua Liu. 2011. Inheritance and expression stability of transgene in transgenic animals. Hereditas. 33(5): 504-511. 14.Kong Q, Wu M, Huan Y, Zhang L, Liu H, et al. 2009. Transgene Expression Is Associated with Copy Number and Cytomegalovirus Promoter Methylation in Transgenic Pigs. PLoS ONE. 4(8): e6679. 15.KONG Qing-Ran, WU Mei-Ling, ZHU Jiang, et al. 2009. Transgene Copy Number and Integration Site Analysis in Transgenic Pig. PBB. 36(12): 1617-1625. 16.Qing-Ran KONG, Zhong-Hua LIU. 2009. INTEGRATION SITE ANALYSIS IN TRANSGENIC PIGS BY THERMAL ASYMMETRIC INTERLACED (TAIL)-PCR AND JUNCTION PCR. Reproduction, fertility and development. 22(1): 371. LIU ZhongHua, SONG Jun, WANG ZhenKun, TIAN JiangTian, KONG QingRan, et al. 2008. Green fluorescent protein (GFP) transgenic pig produced by somatic cell nuclear transfer. Chinese Science Bulletin. 53 (5): 556-560.

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