2012年在中国医科大学获得博士学位

基金项目 中央高校基本科研业务费—重大科技创新项目 (N120820001), 负责人 国家重点基础研究发展计划 (973计划) 课题: 糖尿病胰岛β细胞进行性功能衰竭的分子机制研究, 课题副组长 国家自然科学基金面上项目:锌转运体ZnT3通过调节突触锌离子释放参与tau蛋白磷酸化的分子机制研究,课题副组长 国家自然科学基金面上项目: 锌螯合剂抑制Alzheimer病淀粉样蛋白老年斑形成机理的研究, 课题副组长

代表性论文 1. Chuang Guo, Tao Wang, Wei Zheng, Zhong-Yan Shan, Wei-Ping Teng, Zhan-You Wang. Intranasal deferoxamine reverses iron-induced memory deficits and inhibits amyloidogenic APP processing in a transgenic mouse model of Alzheimer’s disease. Neurobiology of Aging 34, 562–575, 2013. 2. Chuang Guo, Pu Wang, Man-Li Zhong, Tao Wang, Xue-Shi Huang, Jia-Yi Li , Zhan-You Wang. Deferoxamine inhibits iron induced hippocampal tau phosphorylation in the Alzheimer transgenic mouse brain. Neurochemistry International 62, 165–172, 2013. 3. Man-Li Zhong, Chuang Guo, Zhi-Hong Chi, Zhong-Yan Shan, Wei-Ping Teng, Zhan-You Wang. Distribution of zinc and zinc transporters in the mouse ovarian follicles and corpus luteum. Histology and Histopathology 28(11), 1517-1527, 2013. 4.Pu Wang, Pei-Pei Guan, Chuang Guo, Fei Zhu, Konstantinos Konstantopoulos, Zhan-You Wang. Fluid shear stress-induced osteoarthritis: roles of cyclooxygenase-2 and its metabolic products in inducing the expression of proinflammatory cytokines and matrix metalloproteinases. FASEB J, 27(12), 4664-4677, 2013. 5. Liang Peng, Chuang Guo, TaoWang, Baoman Li , Li Gu, Zhanyou Wang. Methodological Limitations in Determining Astrocytic Gene Expression. Front Endocrinol (Lausanne), 25(4), 176, 2013. 6. Guo C, Zhang YX, Wang T, Zhong ML, Yang ZH, Hao LJ, Chai R, Zhang S. Intranasal deferoxamine attenuates synapse loss via up-regulating the P38/HIF-1α pathway on the brain of APP/PS1 transgenic mice. Front Aging Neurosci, 7(104), eCollection, 2015.

参编教材3部