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汪冰

领域:生物产业 学校:东北大学职称:教授

细胞稳态维系机制中的多种网络系统...

具体了解该专家信息,请致电:027-87555799 邮箱 haizhi@uipplus.com

教育背景

1986年毕业于中国药科大学生化制药专业, 1993年去日本留学,于1997年和1999年分别从吉林大学和日本九州大学各获得医学博士学位

工作经历

1999-2004年于加拿大麦吉尔(McGill)大学经历博士后训练。2004-2012年作为资深科学家就职于麦吉尔大学生化系。2013年起任东北大学生命科学与健康学院特聘教授,生化与分子生物学研究所所长,博士生导师,2015年入选 辽宁省高端引进人才百人层面。

项目课题经历

三年来获得国家自然科学基金面上项目两项和参与一项国家重点专项。

论文、成果、著作等

代表性论文 1. Hou Y, Xie G, Liu X, Li G, Jia C, Xu J, Wang B. Minocycline protects against lipopolysaccharide-induced cognitive impairment in mice. Psychopharmacology . 2016,233(5):905-916. (corresponding author) 2. Yue Hou,Ning Li,Guanbo Xie,Jian Wang,Qing Yuan,Congcong Jia,Xia Liu,Guoxun Li,Yingzhan Tang,Bing Wang. Pterostilbene exerts anti-neuroinflammatory effect on lipopolysaccharide-activated microglia via inhibition of MAPK signalling pathways. Journal of Functional Foods. 2015; 19:676-687. (corresponding author) 3. Wang T, Jiang H, Wan L, Zhao Q, Jiang T, Wang B, Wang S. Potential application of functional porous TiO2 nanoparticles in light-controlled drug release and targeted drug delivery. Acta Biomater. 2015 Feb;13:354-63. (corresponding author) 4. Wang T, Zhao P, Zhao Q, Wang B, Wang S. The mechanism for increasing the oral bioavailability of poorly water-soluble drugs using uniform mesoporous carbon spheres as a carrier. Drug Deliv. 2016,23(2):420-428. (corresponding author) 5. Wang B., Nguyen M, Chang N.C, Shore G.C. Fis1, Bap31 and the kiss of death between mitochondria and endoplasmic reticulum. EMBO J. 2;30 (3): 451-2, (2011). 6. Wang B., Heath-Engel H., Zhang D., Nguyen N, Thomas D.Y., Hanrahan J.W. and Shore G.C. BAP31 interacts with Sec61 translocons and promotes retrotranslocation of CFTRDeltaF508 via the derlin-1 complex. Cell 133(6), 1080-92, (2008). 7. Wang, B., Pelletier, J., Massaad, M.J., and Shore, G.C. Yeast Split-ubiquitin Membrane Protein Two-hybrid Screen Identifies BAP31 as a Regulator of the Turnover of Endoplasmic Reticulum-asssociated Protein Tyrosine Phosphatase-like B Mol. Cell. Biol. 24, No 7, (2004). 8. Wang, B., Nguyen, M., Breckenridge, D.G., Stojanovic, M., and Shore, G.C. Uncleaved BAP31 in association with A4 protein at the endoplasmic reticulum is an inhibitor of Fas-initiated release of cytochrome c from mitochondria. J Biol Chem. 278, 14461-14468, (2003). 9. Wang B., Lemay S., Tsai S. and Veillette A. SH2 domain-mediated interaction of inhibitory protein tyrosine kinase Csk with protein tyrosine phosphatase-HSCF. Mol. Cell. Biol. 21, 1077-1088, (2001).

专利、著作版权等

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