教育背景
2001年毕业于大连医科大学临床医学专业,2004年考取清华大学医学院(原中国协和医科大学)硕博连读研究生
工作经历
项目课题经历
1国家自然科学基金青年基金, lin28/let7信号通路调控肿瘤干细胞糖代谢的机制研究
2 辽宁省自然科学基金面上项目,肿瘤恶性转化相关基因Lin28调控乳腺肿瘤细胞糖代谢的机制研究
论文、成果、著作等
1 Jie X, WenBin L, DongSheng G, Lu L, Meng L, WeiTing D, PengXia L, Lei Z, ShiHong L, ChunLan D, Bin Z, Zhongchao H. Neural ganglioside GD2 identifies a subpopulation of mesenchymal stem cells in umbilical cord.Cell Physiol Biochem.2009;23:415-24.
2 Xinxiang L ,Jie X,*,Wei M, Martin N, Hammond S; Yingqun H.Determinants of mRNA recognition and translation regulation by Lin28.Nucleic Acids Research.2011;1-11
3 Jie Xu,*, WenJun Fan, XiXiang Tu, Teng Zhang, ZhiJie Hou, Tao Guo, Xin Shu, Xi Luo, Yang Liu,Fei Peng, Chang Wang, LingZhi Xu, Han Zhou, Quentin Liu.Neural ganglioside GD2+ cells define a subpopulation of mesenchymal stem cells in adult murine bone marrow. Cell Physiol Biochem.2013;32:889-98.
4 Kallen AN, Zhou XB, Xu J, Qiao C, Ma J, Yan L, Lu L, Liu C, Yi JS, Zhang H, Min W, Bennett AM, Gregory RI, Ding Y, Huang Y. The imprinted H19 lncRNA antagonizes let-7 microRNAs. Mol Cell. 2013;10;52(1):101-12.
5 Duanmu J, Jijun C, Jie X, Booth CJ, Hu Z.Effective treatment of chemoresistant breast cancer in vitro and in vivo by a factor VII-targeted photodynamic therapy. Br J Cancer.2011; 26;104(9):1401-9.
6 Ma W, Ma J, Xu J, Qiao C, Branscum A, Cardenas A, Baron AT, Schwartz P, Maihle NJ, Huang Y.Lin28 regulates BMP4 and functions with Oct4 to affect ovarian tumor microenvironment. Cell Cycle. 2013;12(1):88-97.
7 Qiao C, Ma J, Xu J, Xie M, Ma W, Huang Y.Drosha mediates destabilization of Lin28 mRNA targets. Cell Cycle. 2012;11(19):3590-8.
8 Feng C, Neumeister V, Ma W, Xu J, Lu L, Bordeaux J, Maihle NJ, Rimm DL, Huang Y.Lin28 regulates HER2 and promotes malignancy through multiple mechanisms. Cell Cycle. 2012;11(13):2486-94.
9 Lockwood CJ, Huang SJ, Chen CP, Huang Y, Xu J, Faramarzi S, Kayisli O, Kayisli U, Koopman L, Smedts D, Buchwalder LF, Schatz F.Decidual cell regulation of natural killer cell-recruiting chemokines: implications for the pathogenesis and prediction of preeclampsia. Am J Pathol. 2013;183(3):841-56.
10 Liu M, Yang SG, Shi L, Jie X, Gu DS, Liang L, Dong CL, Han ZC.Mesenchymal stem cells from bone marrow show a stronger stimulating effect on megakaryocyte progenitor expansion than those from non-hematopoietic tissues. Platelets. 2010;21(3):199-210.
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