2007年毕业于清华大学北京协和医学院肿瘤研究所分子肿瘤学国家重点实验室，获得博士学位

2007.9-2011.10在美国北卡罗来纳大学医学院Linberger肿瘤中心进行博士后研究，2011.11被提升为研究助理教授，同时作为课题负责人获得北卡大学研究委员会经费的支持，并获得北卡大学“青年科学家发展奖”。2013年入选辽宁省第五批“攀登学者”计划，全职回国到大连医科大学肿瘤干细胞研究院工作

1）大连市十大杰出青年科技人才基金，2016/11-2018/10，执行中，主持 2）国家自然科学基金委重大研究计划培育项目，91540110，利用报告基因系统对环状RNA发生和调控的分子机制研究，2016/01-2018/12，执行中，主持 3）国家自然科学基金委优秀青年基金，81422038，肿瘤研究体系新技术，2015/01-2017/12，执行中，主持 4）国家自然科学基金委面上项目，31471235，RBM4调控RNA选择性剪接的机制及其在肿瘤进展中的作用研究，2015/01-2018/1ᠦ୔

1)Qi Y, Yu J, Han W, Fan X, Qian H, Wei H, Tsai YH, Zhao J, Zhang W, Liu Q, Meng S,Wang Y*,Wang Z*. A splicing isoform of TEAD4 attenuates the Hippo-YAP signalling to inhibit tumour proliferation.Nat Commun.2016 Jun 13;7:ncomms11840. doi: 10.1038/ncomms11840. 2)Wang Yand Wang Z. Design of RNA-Binding Proteins: Manipulate Alternative Splicing in Human Cells with Artificial Splicing Factors.Methods Mol Biol.2016;1421:227-41. 3)Wang Yand Wang Z. Efficient backsplicing produces translatable circular mRNAs.RNA2015 21(2):172-9. 4)Yang Wang*, Dan Chen, Haili Qian, Yihsuan S. Tsai, Shujuan Shao, Quentin Liu, Daniel Dominguez, Zefeng Wang*. The Splicing Factor RBM4 Controls Apoptosis, Proliferation, and Migration to Suppress Tumor Progression.Cancer Cell2014 Sep 8;26(3):374-89. 5)Yang Wang* and Zefeng Wang*.Systematical identification of splicing regulatory cis-elements and cognate trans-factors.Methods. 2013 Aug 22. doi:pii: S1046-2023(13)00326-5. 10.1016/j.ymeth.2013.08.019. (* Correspondence author) 6)Yang Wang, Zefeng Wang and Traci Hall. Engineered proteins with PUF scaffold to manipulate RNA metabolism.FEBS Journal. 2013; 280 (16):3755-67. (Invited review, Cover article) 7)Yang Wang, Xinshu Xiao, et. al. A Complex Network of Factors with Overlapping Affinities Control Splicing Repression by Intronic Elements.Nature Structural & Molecular Biology. 2013 Jan; 20(1):36-45 8)Yang Wang, Meng Ma, Xinshu Xiao, et.al. Intronic Splicing Enhancers, Cognate Splicing Factors and Context Dependent Regulation Rules.Nature Structural & Molecular Biology. 2012 Oct; 19(10):1044-52 9)Wang Y, Cheong G, Tanaka Hall TM, Wang Z. Engineering splicing factors with designed specficities.Nature Methods. 2009, 6 (11): 825-830 (Recommended by Faculty of 1000) 10)Yang Wang, Jing Yu and Qimin Zhan. BRCA1 regulates caveolin-1 expression and inhibits cell invasiveness.Biochem Biophys Res Commun. 2008 30; 370 (2): 201-6 11) Yang Wangand Qimin Zhan. Cell cycle dependent expression of centrosomal Nlp in human cells is regulated by the anaphase-promoting complex (APC).J Biol Chem, 2007, 282(24), 17712-17719. 12) Shujuan Shao*,Yang Wang*, Shunqian Jin*, et al. Gadd45a interacts with aurora-a and inhibits its kinase activity.J Biol Chem, 2006, 281(39), 28943-28950. (* Co-first author)