首页 > 专家库
左云飞

领域:生物产业 学校:大连医科大学职称:教授

主要致力于肿瘤发生、转移及其机制的研究。研究方向包括:淋巴瘤淋巴道转移潜能及其机制;C-型凝集素在结肠癌肝转移中的作用及其机制;结肠癌的早期诊断标志物;淋巴瘤的诊断标志物;胃癌肝转移的发生及其机制。...

具体了解该专家信息,请致电:027-87555799 邮箱 haizhi@uipplus.com

教育背景

相继获得大连医科大学生物化学与分子生物学专业博士学位、硕士学位

工作经历

项目课题经历

1. LSECtin对胃癌肝转移能力的影响及其机制的研究,主持人,国家自然科学基金,项目负责人。 2. C型凝集素LSECtin在淋巴瘤淋巴道转移中的作用,主持人,国家自然科学基金,项目负责人。 3.国家自然科学基金面上项目,P2X7R参与淋巴瘤淋巴道转移潜能及机制,项目负责人。 4.国家自然科学基金面上项目,C-型凝集素LSECtin 在淋巴瘤淋巴道转移中的作用及其机制,项目负责人。 5.国家自然科学基金面上项目,DC-SIGNR在结肠癌肝转移中的作用及其机制,项目执行负责人。 6.辽宁省省自ᠦ୔

论文、成果、著作等

1.Zhang Y,Zhang Q,Zhang M,Yuan M,Wang Z,Zhang J,Zhou X,Zhang Y,Lin F,Na H,Ren S,Zuo Y. DC-SIGNR by influencing the lncRNA HNRNPKP2 upregulates the expression of CXCR4 in gastric cancer liver metastasis.Mol Cancer.2017 Apr 13;16(1):78. IF=7.776(通讯作者) 2.Na H,Liu X,Li X,Zhang X,Wang Y,Wang Z,Yuan M,Zhang Y,Ren S,Zuo Y. Novel roles of DC-SIGNR in colon cancer cell adhesion, migration, invasion, and liver metastasis.J Hematol Oncol.2017 Jan 21;10(1):28. IF=7.333(通讯作者) 3.Novel roles of liver sinusoidal endothelial cell lectin in colon carcinoma cell adhesion, migration and in-vivo metastasis to the liver. Gut. 2013 Aug,62(8):1169-78.他引17,IF=13.319(第一作者) 4. DAC can restore expression of NALP1 to suppress tumor growth in colon cancer. CELL DEATH & DISEASE, 2015,6他引1,IF=5.177(通讯作者) 5. DC-SIGN, DC-SIGNR and LSECtin: C-Type Lectins for Infection. International Reviews of Immunology, 2014,33:54-66.他引6,IF=5.280(通讯作者) 6. Novel roles of DC-SIGNR in colon cancer cell adhesion, migration, invasion and liver metastasis. Journal of Hematology&Oncology. 2016. IF= 6.263(通讯作者) 7. Silencing P2X7 receptor downregulates the expression of TCP-1 involved in lymphoma lymphatic metastasis. Oncotarget. 2015 ; 6 ( 39 ): 42105–42117. IF=5.008(通讯作者) 8. The clinical significance of DC-SIGN and DC-SIGNR, which are novel markers expressed in human colon cancer. PLoS ONE 2014,12,他引2,IF=3.543(通讯作者) 9. Activated P2X7 receptor upregulates the expression levels of NALP3 in P388D1 murine macrophage like cells. Mol Med Rep. 2015 Feb,11(2):1542-6.IF=1.554(通讯作者) 10.Low expression of DC-SIGNR in Non-Hodgkin lymphoma and significant correlations with LDH andβ2-microglobulin. Biochemistry and Cell Biology, 2013 Aug,91(4):214-20.他引2,IF= 2.6(通讯作者) 11. Niclosamide inhibits colon cancer progression through downregulation of the Notch pathway and upregulation of the tumor suppressor miR-200 family. international journal of molecular medicine. 2016 ; 38 ( 3 ): 776-784. IF=2.348(通讯作者) 12. Low expression of dendritic cell-specific intercellular adhesion molecule-grabbing nonintegrin-related protein in lung cancer and significant correlations with brain metastasis and natural killer cells. Molecular and Cellular Biochemistry. 2015 ; 407 ( 1-2 ): 151-160.他引2,IF= 2.613(通讯作者)

专利、著作版权等

声明:本站专家信息来源于各高校官网。