教育背景
2013年6月毕业于中国医学科学院&北京协和医学院药物研究所,获得理学博士学位
工作经历
项目课题经历
承担国家自然科学基金项目2项、省教育厅项目1项等
论文、成果、著作等
1) C. Wang, X. Huo, Z. Luan, F. Cao, X. Tian, X. Zhao, C. Sun*, L. Feng, J. Ning, B. Zhang, X. Ma*. Alismanin A, a Triterpenoid with a C34 Skeleton from Alisma orientale as a Natural Agonist of Human Pregnane X Receptor. Org. Lett. 2017, 19, 5645−5648.
2) T. Liu, Q.L. Yan, L. Feng, X.C. Ma, X.G. Tian, Z.L. Yu, J. Ning, X.K. Huo, C.P. Sun, C. Wang*, J.N. Cui*. Isolation of γ-Glutamyl-Transferase Rich-Bacteria from Mouse Gut by a Near-Infrared Fluorescent Probe with Large Stokes Shift. Anal. Chem., 2018, 90, 9921−9928.
3) X.X. Gao, C.P. Sun, Z.L. Yu, J. Cang, X.G. Tian, X.K. Huo, L. Feng, X.G. Liu, C. Wang*, B.J. Zhang, X.C. Ma*. Correlation analysis between the chemical contents and bioactivity for the quality control of Alismatis Rhizoma. Acta Pharm. Sin. B 2018, 8, 242–251.
4) L. Feng, Y.L. Yang, X.K. Huo, X.G. Tian, Y.J Feng, H.W Yuan, L.J. Zhao, C. Wang*, P. Chu, F.D. Long, W. Wang*, X.C. Ma*. Highly selective NIR probe for intestinal β-Glucuronidase and Highthroughput screening inhibitors to therapy intestinal damage. ACS Sensors, 2018, DOI: 10.1021/acssensors.8b00471.
5) X. Gao, S. Huang, P. Dong, C. Wang,* J. Hou, X. Huo, B. Zhang, T. Ma, X, Ma*. Horseradish peroxidase (HRP): a tool for catalyzing the formation of novel bicoumarins. Catal. Sci. Technol., 2016, 6(10): 3585-3593.
6) C. Wang, X.K. Huo, X.G. Tian, M. Xu, P.P. Dong, Z. Luan, X. Wang, B. Zhang, B. Zhang, S. Huang, S. Deng, X. Ma. Inhibition of melatonin metabolism in humans induced by chemical components from herbs and effective prediction of this risk using a computational model. Br. J. Pharmacol., 2016, 173 3261–3275.
7) M. Xu, P. Dong, X. Tian, C. Wang*, X.K. Huo, B.J. Zhang, L. Wu, S. Deng, X.C. Ma*. Drug interaction study of natural steroids from herbs specifically toward human UDP-glucuronosyl transferase (UGT) 1A4 and their quantitative structure activity relationship (QSAR) analysis for prediction. Pharmacol. Res., 2016, 110, 139–150.
8) Y. Cui, X. Tian, J. Ning, C. Wang,* Z. Yu, Y. Wang, X. Huo, L. Jin, S. Deng, B. Zhang, X. Ma*. Metabolic profile of 3-acetyl-11-keto-β-boswellic acid and 11-keto-β-boswellic acid in human preparations in vitro, species differences, and bioactivity variation. The AAPS Journal, 2016, 18, 1273–1288.
9) C. Wang, Q. Yan, Y. Ma, C. Sun, C. Chen, X. Tian, X. Han, C. Wang,* S. Deng, Xiao-Chi Ma*. ent-Abietane and tigliane diterpenoids from the roots of Euphorbia fischeriana and their inhibitory effects against Mycobacterium smegmatis. J. Nat. Prod., 2017, 80(5): 1248-1254.
10) X.R. Zhao, X.K. Huo, P.P. Dong, C. Wang,* S.S. Huang, B.J. Zhang, H.L. Zhang, S. Deng, K.X. Liu, Xiao-Chi Ma*. Inhibitory effects of highly oxygenated lanostane derivatives from the Fungus Ganoderma lucidum on P-glycoprotein and α-glucosidase. J. Nat. Prod., 2015, 78, 1868−1876.
11) Z. Mai, K. Zhou G. Ge, C. Wang,* X. Huo, P. Dong, S. Deng, B. Zhang, H. Zhang, S. Huang, X. Ma*. Protostane triterpenoids from the rhizome of Alisma orientale exhibit inhibitory effects on human carboxylesterase 2. J. Nat. Prod., 2015, 78, 2372−2380.
12) C. Wang, C. Li, J. Yang, J. Ma, X. Chen, Q. Hou, D. Zhang*. Anti-inflammatory sesquiterpene derivatives from the leaves of Tripterygium wilfordii. Journal of Natural Products, 2013, 76, 85–90.
13) A.H. Wang, X.G. Tian, Y.L. Cui, X.K. Huo, B.J. Zhang, S. Deng, L. Feng, X.C. Ma, J.M. Jia*, C. Wang*. Diterpenoids from the roots of Euphorbia ebracteolata and their inhibitory effects on human carboxylesterase 2. Phytochemistry, 2018, 146, 82–90.
14) B Wang, Y.L. Wei, X.Y. Zhao, X.G. Tian, J. Ning, B.J. Zhang, S. Deng, D.W. Li*, X.C. Ma*, C. Wang*. Unusual ent-atisane type diterpenoids with 2-oxopropyl skeleton from the roots of Euphorbia ebracteolata and their antiviral activity against human rhinovirus 3 and enterovirus 71. Bioorg. Chem., 2018, 81, 234–240.
15) Zhenlong Yu, Yunlong Wei, Xiangge Tian, Qiulong Yan, Qingsong Yan, Xiaokui Huo, Chao Wang*, Chengpeng Sun, Baojing Zhang, Xiaochi Ma*. Diterpenoids from the roots of Euphorbia ebracteolata and their anti-tuberculosis effects. Bioorg. Chem., 2018, 77, 471–477.
16) Chunhui Han, Yulin Peng, Yifei Wang, Xiaokui Huo, Baojing Zhang, Dawei Li*, Aijing Leng, Houli Zhang, Xiaochi Ma*, Chao Wang*. Cytotoxic ent-Abietane-type diterpenoids from the roots of Euphorbia ebracteolata. Bioorg. Chem., 2018, 81, 93–97.
17) P. Li, C. Suna, Y. Wang, S. Wang, C. Yan, S. Deng, X. Huo, L. Feng, C. Wang,* Y. Tian, B. Zhang, X. Ma*. Efficiently regioselective glucosylation of estrogen analogues mediated by fungus Rhizopus oryzae AS 3.2380. Catal. Commun., 2017, 97, 106–110.
18) C. Wang, X. Huo, B. Zhang, C. Sun, X. Tian, S. Deng, B. Li, W. Wang. Dong, X. Ma. Highly regioselective glucosylation of alcoholic hydroxyls of protostane triterpenoids mediated by fungal biotransformation. Catal. Commun., 2017, 89, 40–43.
19) M. Xu, X. Huo, X. Tian, P. Dong, C. Wang,* S. Huang, B. Zhang, H. Zhang, S. Deng, X. Ma*. Microbial transformation of diosgenin by Cunninghamella blakesleana AS 3.970 and potential inhibitory effects on P-glycoprotein of its metabolites. RSC Adv., 2015, 5, 78081-78089.
20) C. Wang, P. Dong, L. Zhang, X. Huo, B. Zhang, C. Wang, S. Huang, X. Wang,* J. Yao, K. Liu, X. Ma. Regio- and stereo- selective oxidation of β-boswellic acids transformed by filamentous fungi. RSC Adv., 2015, 5, 12717–12725.
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