教育背景
2015年3月毕业于中国科学院大学,获工学博士学位。
工作经历
2008年至2018年期间于中科院大连化学物理研究所学习和工作
项目课题经历
主持国家自然科学基金1项,广东省中药药效物质基础与创新药物研究重点实验室开放课题1项,辽宁省“兴辽英才计划”青年拔尖人才项目1项;作为主要参与人参加了多项国家自然科学基金、重大传染病防治专项(2012ZX10002011)和重大新药创制专项(2012ZX09506001)等国家科技重大专项的研究工作
论文、成果、著作等
(1) Zhang JN, Bi R, Meng Q, Wang CY, Huo XK, Liu ZH, Wang C, Sun PY, Sun HJ, Ma XD, Wu JJ*, Liu KX*. Catalpol Alleviates Adriamycin‐Induced Nephropathy by Activating the SIRT1 Signalling Pathway In Vivo and In Vitro. Br J Pharmacol. 2019, 176 (23): 4558-4573. (IF =6.583, Q1区)
(2) Wu JJ, Cao YF, Feng L, He YQ, Hong JY, Dou TY, Wang P, Hao DC, Ge GB*, Yang L. A naturally occurring isoform-specific probe for highly selective and sensitive detection of human cytochrome P450 3A5. J Med Chem. 2017, 60 (9): 3804-3813. (IF = 6.253, Q1区)
(3) Wu JJ, Ge GB, He YQ, Wang P, Dai ZR, Ning J, Hu LH, Yang L*. Gomisin A is a novel isoform-specific probe for the selective sensing of human cytochrome P450 3A4 in liver microsomes and living cells. AAPS J. 2016, 18(1): 134-145. (IF = 3.804, Q1区)
(4) Wu JJ, Cao YF, Zhang YY, Liu Y, Hong JY, Zhu LL, Ge GB, Yang L*. Deoxyschizandrin, a Naturally Occurring Lignan, Is a Specific Probe Substrate of Human Cytochrome P450 3A. Drug Metab Dispos. 2014, 42(1): 94-104. (IF = 3.640, Q1区)
(5) Wu JJ, Ai CZ, Liu Y, Zhang YY, Jiang M, Fan XR, Lv AP, Yang L*. Interactions between Phytochemicals from Traditional Chinese Medicines and Human Cytochrome P450 Enzymes. Curr Drug Metab. 2012. 13: 599-614. (IF = 2.655, Q2区)
(6) He W# , Wu JJ# , Ning J, Xin H, He YQ, Ge GB*, Xu W*. Inhibition of human cytochrome P450 enzymes by licochalcone A, a naturally occurring constituent of licorice. Toxicol in Vitro. 2015, 29: 1569-1576. (IF = 3.105, Q1区)
(7) Li JN, Cao YF, He RR, Ge GB, Guo B*, Wu JJ *. Evidence for Shikonin acting as an active inhibitor of human carboxylesterases 2: Implications for Herb-Drug Combination. Phytother Res. 2018, 32(7): 1311-1319. (IF = 3.349, Q1区)
专利、著作版权等
获授权发明专利 5 件,参与撰写专著4部
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