教育背景
工作经历
博士毕业后于大连汉信生物制药有限公司从事博士后研究工作两年,后获国家留学基金委资助赴美国弗吉尼亚大学访学及博士后工作两年。
项目课题经历
目前主持并完成国家自然科学基金面上项目2项;中国博士后科学基金、辽宁省自然科学基金、辽宁省高等学校优秀人才计划项目各1项;辽宁省教育厅项目2项,
论文、成果、著作等
1. Nawaz W, Zhou Z, Deng S, Ma X, Ma X, Li C, Shu X*. Therapeutic Versatility of Resveratrol Derivatives. Nutrients. 2017;9(11). pii: E1188.
2. Yang Y, Li C, Li H, Wu M, Ren C, Zhen Y, Ma X, Diao Y, Ma X, Deng S, Liu J, Shu X*. Differential sensitivities of bladder cancer cell lines to resveratrol are unrelated to its metabolic profile. Oncotarget. 2017;8(25):40289-304.
3. Zhao D, Huang S, Qu M, Wang C, Liu Z, Li Z, Peng J, Liu K, Li Y, Ma X, Shu X*. Structural optimization of diphenylpyrimidine derivatives (DPPYs) as potent Bruton's tyrosine kinase (BTK) inhibitors with improved activity toward B leukemia cell lines. Eur J Med Chem. 2017;126:444-55.
4. Huang M, Chen Z, Zhang L, Huang Z, Chen Y, Xu J, Zhang J, Shu X*. Screening and biological evaluation of a novel STAT3 signaling pathway inhibitor against cancer. Bioorg Med Chem Lett. 2016;26(21):5172-76.
5. Shu X, Keller TC 4th, Begandt D, Butcher JT, Biwer L, Keller AS, Columbus L, Isakson BE. Endothelial nitric oxide synthase in the microcirculation. Cell Mol Life Sci. 2015;72(23):4561-75.
6. Shu XH, Wang LL, Li H, Song X, Shi S, Gu JY, Wu ML, Chen XY, Kong QY, Liu J. Diffusion Efficiency and Bioavailability of Resveratrol Administered to Rat Brain by Different Routes: Therapeutic Implications. Neurotherapeutics. 2015;12(2):491-501.
7. Hu Y, Li S, Liu F, Geng L, Shu X*, Zhang J. Discovery of novel nonpeptide allosteric inhibitors interrupting the interaction of CDK2/cyclin A3 by virtual screening and bioassays. Bioorg Med Chem Lett. 2015;25(19):4069-73.
8. Hu Y, Li C, Li H, Li M, Shu X*. Resveratrol-mediated reversal of tumor multi-drug resistance. Curr Drug Metab. 2014;15(7):703-10.
9. Shu XH, Li H, Sun XX, Wang Q, Sun Z, Wu ML, Chen XY, Li C, Kong QY, Liu J. Metabolic patterns and biotransformation activities of resveratrol in human glioblastoma cells: relevance with therapeutic efficacies. PLoS One. 2011;6(11):e27484.
10. Shu XH, Li H, Sun Z, Wu ML, Ma JX, Wang JM, Wang Q, Sun Y, Fu YS, Chen XY, Kong QY, Liu J. Identification of metabolic pattern and bioactive form of resveratrol in human medulloblastoma cells. Biochem Pharmacol. 2010;79(10):1516-25.
专利、著作版权等
声明:本站专家信息来源于各高校官网。