教育背景
2005/3 - 2008/8,韩国明知大学,微生物学,博士,导师:徐胄源
2002/9 - 2004/8,韩国明知大学,微生物学,硕士,导师:徐胄源
1998/9 - 2002/9,东北大学,环境工程,学士,导师:徐新阳
工作经历
2015/1 - 至今,大连医科大学,基础医学院,副教授
2012/1 - 2014/12,大连医科大学,基础医学院,讲师
2009/7 – 2011/12,大连理工大学化学工程与技术博士后流动站,博士后
项目课题经历
1. 辽宁省教育厅科学研究一般项目:不同分泌型母亲哺乳期HMO成份对子代肠道双歧杆菌的影响研究;项目编号:L20160003;2016/07~2019/06;在研、主持
2. 第60批中国博士后基金面上项目:γδT17 细胞介导混合菌群结肠黏膜保护作用的机制研究;项目编号:2016M601317;2016/10~2018/09;在研、主持
3. 辽宁省自然科学基金项目:植物乳杆菌DM9218对高脂饮食诱导的非酒精性脂肪肝的防治作用及机制;项目编号2015020262;2015/07~2018/06;在研、ᠦ
论文、成果、著作等
1 Li, Ming (*); Gao, Jiali; Tang, Yan; Liu, Meishuo; Wu, Sijin; Qu, Kunli; Long, Xiangyu; Li, Huajun; Liu, Min; Liu, Yinhui; Yuan, Jieli; Mao, Lei; Liu, Yu; Zheng, Xiliang; Wang, Erkang; Wang, Jin(*); Yang, Yongliang (*), Traditional herbal medicine-derived sulforaphene LFS-01 reverses colitis in mice by selectively altering the gut microbiota and promoting intestinal gamma-delta T cells, Front Pharmacol, 2018.1.9, 8: 959. IF=4.40通讯作者
2 Liang, Wei (#); Mao, Shanshan (#); Sun, Shijie (#); Li, Ming, Li, Zhi; Yu, Rui; Ma, Tonghui; Gu, Jianguo; Zhang, Jianing; Taniguchi, Naoyuki; Li, Wenzhe (*), Core fucosylation of the T cell receptor is required for T cell activation Front Immunol, 2018.1.29, 9: 78. IF=6.429
3 Li, Ming (#); Wang, Bing (#); Sun, Xiaotong; Tang, Yan; Wei, Xiaoqing; Ge, Biying; Tang, Yawei; Deng, Ying; He, Chunyang; Yuan, Jieli (*); Li, Xia (*), Upregulation of intestinal barrier function in mice with DSS-induced colitis by a defined bacterial consortium is associated with expansion of IL-17A producing gamma delta T cells, Front Immunol, 2017.7.12, 8: 824~824. IF=6.429
4 Tang Y, Wu Y, Huang Z, Dong W, Deng Y,Li M(*), Yuan J*. Administration of probiotic mixture DM#1 ameliorated 5-fluorouracil-induced intestinal mucositis and dysbiosis in rats. Nutrition. 2016. Accepted. DOI: 10.1016/j.nut.2016.05.003, IF=3.42 通讯作者
5 Li M, Chen Y, Wu S, Tang Y, Deng Y, Yuan J, Dong J, Li H, Tang L. TmcN is involved in ATP regulation of tautomycetin biosynthesis in Streptomyces griseochromogenes. Biochem Biophys Res Commun. 2016 Sep 9;478(1):221-6. IF=2.371
6 Li M, Li Z, Wen S, Liu Y, Wang Y, and Tang L*. Transplantation of a bacterial consortium ameliorates Trinitrobenzenesulfonic acid-induced colitis and intestinal dysbiosis in rats. Future Microbiol. 2016, 11:887-902. IF=3.637
7 Ma Z, Wang B, Wang M, Sun X, Tang Y, Li M, Li F, and Li X*. TL1A increased IL-6 production on fibroblast-like synoviocytes by preferentially activating TNF receptor 2 in rheumatoid arthritis. Cytokine 2016 83:92-98. IF=2.940
8 Mei L, Tang Y, Li M, Yang P, Liu Z, Yuan J, Zheng P*. Co-Administration of Cholesterol-Lowering Probiotics and Anthraquinone from Cassia obtusifolia L. Ameliorate Non-Alcoholic Fatty Liver. PLoS One. 2015 Sep 16;10(9):e0138078. IF=3.057
9 Li M, Liang P, Li Z, Wang Y, Zhang G, Gao H, Wen S, Tang L*, Fecal microbiota transplantation and bacterial consortium transplantation have comparable effects on the re-establishment of mucosal barrier function in mice with intestinal dysbiosis. Front Microbiol, 2015, 07, 6:692. doi: 10.3389/fmicb.2015.00692 IF=4.165
10 Li M, Zhou H, Guan Y, Peng H, Wang S, Zhang P, Su B. Positive hepatitis B surface antibody is associated with reduced risk of diabetes mellitus in retired female Chinese workers. J Diabetes, 8 (2016) 15 –161, IF=2.500
11 Li M, Zhu L, Xie A, and Yuan J*, Oral Administration of Saccharomyces boulardii Ameliorates Carbon Tetrachloride-Induced Liver Fibrosis in Rats via Reducing Intestinal Permeability and Modulating Gut Microbial Composition, Inflammation, 2015, 38(1):170-9. IF=2.2
12 Li M, Yang D, Yuan L, Xie A, and Yuan J*, Screening and characterization of purine nucleoside degrading lactic acid bacteria isolated from Chinese sauerkraut and evaluation of the serum uric acid lowering effect in hyperuricemic rats. PLoS One, 2014, (9) e105577. IF=3.5
13 Li M, Li W, Wen S, Liu Y, and Tang L*, Effects of ceftriaxone-induced intestinal dysbacteriosis on dendritic cells of small intestine in mice,Micorobiol Immunol, 2013, 57(8):561-8. IF=1.545
14 Gao F, Li M, Liu Y, Gao C, and Tang L*, Intestinal dysbacteriosis induces changes of T lymphocyte subpopulations in Peyer’s patches of mice and orients the immune response towards humoral immunity, Gut Pathog, 4(1), p19-21, 2012.(共同一作)IF=2.738
15 Wang FX, Deng AJ, Li M, Wei JF, Qin HL, Wang AP*, (3S)-1,2,3,4 -Tetrahydro-β-carboline-3-carboxylic acid from Cichorium endivia. L induces apoptosis of human colorectal cancer HCT-8 cells, Molecules, 18(1), p418-29, 2012. IF=2.4
16 Meng L, Li M, Yang SH, Kim TJ, and Suh JW*, Intracellular ATP levels affecting secondary metabolite production in Streptomyces sp., Biosci Biotechnol Biochem, 75(8), p1576-1581, 2011. (共同一作)IF=1.2
17 Li M, Lee SK, Yang SH, Kim TJ, and Suh JW*, ATP modulates the growth of specific microbial strains, Current Microbiol, 62, p84-89, 2011. IF=1.8
18 Li M, Kim TJ, Kwon HJ, and Suh JW*, Effects of extracellular ATP on the physiology of Streptomyces coelicolor A3(2), FEMS Microbiol Lett, 286, p24-31, 2008. IF=2.0
19 Kim TJ, Li M, Meng L, Kwon HJ, and Suh JW*, ATP treatment improves the microbial ecology in soil, J Biotechnol, Supplementa1 pS264, 2008. IF=2.7
20 Huh JH, Kim DJ, Zhao XQ, Li M, Jo YY, Yoon TM, Shin SK, Yong JH, Ryu YW, Yang YY, and Suh JW*, Widespread activation of antibiotic biosynthesis by S-adenosylmethionine in streptomycetes, FEMS Microbiol Lett, 238, p439-447, 2004. IF=2.0
专利、著作版权等
1 唐立,李明 (参编),微生态学基础,《医学微生态学》,李兰娟 院士 主编,人民卫生出版社,国家十二五规划教材,2014年6月出版。
2 李华军(主编),李明 (副主编),《健康之星—双歧杆菌》,辽宁科学技术出版社,拟于2016年6月出版。
3 董建一(主编),李明 (副主编),《医学实验动物常用数据》,辽宁科学技术出版社,拟于2016年5月出版。
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