1994年毕业于牡丹江医学院。1998年8月于佳木斯大学医学院取得硕士学位，999年11月至2004年3月获得日本文部省奖学金并考取了日本高知医科大学生理学专业的博士，

自1998年7月至2006年7月在黑龙江省医院放射免疫中心工作，历任主治医师、副主任医师。2006年8月进入大连医科大学工作，期间于2008年3月进入大连市经济技术开发区富生制药有限公司联合大连医科大学博士后流动工作站

[1] Zhang D, Zhu L, Li C, Mu J, Fu Y, Zhu Q, Zhou Z, Liu P, Han C. Sialyltransferase7A, a Klf4-responsive gene, promotes cardiomyocyte apoptosis during myocardial infarction. Basic Res Cardiol. 2015;110(3):484. doi: 10.1007/s00395-015-0484-7. (corresponding author, Impact Factor: 6.008) [2] Yu XJ, Zhang DM, Jia LL, Qi J, Song XA, Tan H, Cui W, Chen W, Zhu GQ, Qin DN, Kang YM. Inhibition of NF-κB activity in the hypothalamic paraventricular nucleus attenuates hypertension and cardiac hypertrophy by modulating cytokines and attenuating oxidative stress. Toxicol Appl Pharmacol. 2015 Mar 7. pii: S0041-008X(15)00080-0. doi: 10.1016/j.taap.2015.02.023. (IF：3.975共同第一) [3] 张冬梅 茶色素对离体蟾蜍心肌收缩力的保护作用。中国实验方剂学杂志2015；21(12):90-94.通讯作者 [4] 隋晓倩；于德钦；张冬梅。子宫内膜容受性各相关标志物研究进展。生殖与避孕 2015; 35(3):185-190.通讯作者 [5] Kang, YM; Zhang, DM; Yu, XY; Yang, Q; Qi, J; Su, Q; Suo, YP; Yue, LY; Zhu, GQ; Qin, DN. Chronic infusion of enalaprilat into hypothalamic paraventricular nucleus attenuates angiotensin II-induced hypertension and cardiac hypertrophy by restoring neurotransmitters and cytokines. Toxicology and applied pharmacology 2014 ; 274 : 436-444 (IF：3.975共同第一) [6 Qi J, Zhang DM, Suo YP, Song XA, Yu XJ, Elks C, Lin YX, Xu YY, Zang WJ, Zhu Z, Kang YM. Renin-Angiotensin System Modulates Neurotransmitters in the Paraventricular Nucleus and Contributes to Angiotensin II-Induced Hypertensive Response. Cardiovasc Toxicol 2013:13:48-54. (Impact Factor: 2.05) Zhang DM为共同第一作者。 [7] Zhang DM, Wei JX, Wang J, Liu S, Wang XQ, Yan Q. LeY expression is required for integrin αvβ3-mediated endometrial receptivity. Ferti Steril. 2011;95:1446-1451. (Impact Factor: 4.295) [8] Zhang D, Sato T, Gong D, Fu L, Dai S, Xu H, Wu Q, Wang D, Peng Y, Sun Y. Neural reflex hypotension induced by very small dose of hypertonic NaCl solution in rats. Chin J Physiol. 2009;521:8-15. (Impact Factor: 1.275) [9]张冬梅，崔晓光.高渗盐水诱发大鼠短暂性低血压的神经调节.中国心血管病研究杂志. 2006;4:456-458. [10] Yamasaki F, Furuno T, Sato K, Zhang D, Nishinaga M, Sato T, Doi Y, Sugiura T. Association between arterial stiffness and platelet activation. J Hum Hypertens. 2005;19:527-533. [11] Ando M, Katare RG, KakinumaY, Zhang D, Yamasaki F, Muramoto K, Sato T. Efferent vagal nerve stimulation protects heart against ischemia-induced arrhythmias by preserving connexin43 protein. Circulation. 2005;112:164-170. [12] Zhang D, Ando M, Yamasaki F, Sato T. Carotid-sinus baroreflex modulation of core and skin temperatures in rats: an open-loop approach. Jpn J Physiol. 2003;53:461-466.