2004/09 - 2007/07，生理学博士，大连医科大学与新加坡国立大学联合培养 1989/09 - 1992/07，生理学系硕士，华中科技大学同济医学院 1982/09 - 1987/07，医疗系学士，滨州医学院

2000/09 - 至今， 教授、博士研究生导师，大连医科大学 2009/01 - 2009/05，Research Fellow，Department of Pharmacology, Yong Loo Lin School of Medicine, Centre for Life Sciences, National University of Singapore, Singapore，PI: Dr. Gavin S Dawe 2005/09 - 2008/07，Research Scientist，Institute of Molecular and Cellbiology, Department of Clinical Research, Singapore General Hospital, Singapore，PI: Zhicheng Xiao 1999/12 - 2000/08，高级访问学者，中国科学院上海生理所赵志奇教授研究组 1996/01 - 1996/12，高级访问学者，华中科技大学同济医学院实验医学中心李之望教授膜片钳实验室 1987/07 - 2000/07，助教、讲师、副教授，滨州医学院

发布时间：2018-09-25 08:49:57 本文被阅次数：725 我要打印 字号：大 中 小 李韶 李韶，女，博士，辽宁省特聘教授，博士及硕士研究生导师。 辽宁省脑疾病神经保护与损伤修复重点实验室主任、辽宁省省级高校脑疾病研究重点实验室主任、大连医科大学生理学教研室主任兼书记。 长期从事神经生理学研究，主持完成国家级课题5项，省部级课题10项，近5年通讯作者发表SCI论文25篇，第一完成和合作完成人身份获国际专利4项、国内专利2项，教育部科技进步二等奖1项，省科技进步二等奖2项、三等奖2ᠦ୔

1.Ntim M#, Li QF #, Zhang Y#, Liu XD, Li N, Sun HL, Zhang X, Khan B, Wang B, Wu Q, Wu XF, M QH*, Zhao J*, Li S*. TRIM32 deficiency impairs synaptic plasticity by excitatory-inhibitory imbalance via notch pathway. Cerebral Cortex, 2020, in press. 2.Huang R#, Yuan DJ#, Li S#, Liang XS, Gao Y, Lan XY, Qin HM, Ma YF, Xu GY, Schachner M，Sytnyk V, Boltze J, Ma QH*, and Li S*. NCAM regulates temporal specification of neuralprogenitor cells via profilin2 during corticogenesis. Journal of cell biology,2019,12,online. 3.Wang XG#，Zhu DD#, Li N#, Huang YL，Wang YZ，Zhang T，Wang CM，Wang B，Peng Y，Ge BY，Li S*，Zhao J* Scorpion Venom Heat-resistant Peptide is Neuroprotective against Cerebral Ischemia-Reperfusion Injury associated with NMDA-MAPKs Pathway，Neuroscience Bulletin，2019 Sep 9. doi: 10.1007/s12264-019-00425-1. 4.Lan YL*, Li S*, Lou JC，Ma XC, Zhang B. The potential roles of dopamine in traumatic brain injury: a preclinical and clinical update Am J Transl Res 2019;11(5):2616-2631 5.Chen JJ#, Yang G#, Yan QQ, Zhao J* and Li S* Exosome-encapsulated microRNAs as promising biomarkers for Alzheimer's disease. J Rev Neurosci. 2019 Jul 18. [Epub ahead of print] 6.Lan YL, Lou JC, Jiang XW, Wang X, Xing JS, Li S*,Zhang B*. A research update on the anticancer effects of bufalin and its derivative. Oncology Letters, 2019 Apr;17(4):3635-3640. 7.Li QF#, Wu XF#, Na XY, Ge BY, Wu Q, Guo XW, Ntim M, Zhang Y, Sun YP, Yang JY, Xiao ZC*, Zhao J* and Li S*. Impaired cognitive function and altered hippocampal synaptic plasticity in mice lacking dermatan sulfotransferase Chst14/D4st1, Frontiers in Molecular Neuroscience,11 February 2019 doi: 10.3389/fnmol.2019.00026 8.Wang ZT, Lv MH, Zhang Y, Ji WL, Lei L, Wang W, Fang LP, Wang LW, Fan Y, Wang J, Li ZY, Wang J, Wang TW, Dou F, Wang QW, Wang XL, Li S*, Ma QH*, Xu RX*. Disrupted‐in‐schizophrenia‐1 protects synaptic plasticity in a transgenic mouse model of Alzheimer’s disease as a mitophagy receptor. Aging Cell, 2019 Feb;18(1):e12860. 9.Wang B#, Wu Q#, Lei L#, Sun H, Zhang X, Zhang Y, Michael N, Ge B, Xin Y*, Zhao J*, Li S* Long-term social isolation inhibits autophagy activation, induces postsynaptic dysfunctions and impairs spatial memory. Experimental Neurology, 2018, Sep 13. pii: S0014-4886(18)30465-5. 10.Chen JJ, Zhao B, Zhao J*, Li S*. Potential roles of exosomal microRNAs as diagnostic biomarkers and therapeutic application in Alzheimer’s disease. Neural Plasticity. 2017; 2017:7027380. doi: 10.1155/2017/7027380. Epub 2017 Jul 9. 11.Lan YL, Chen JJ, Hu G, Xu J, Xiao M*, Li S*. Aquaporin 4 in astrocytes is a target for therapy in Alzheimer's disease. Current Pharmaceutical Design. Current Pharmaceutical Design. 2017;23(33):4948-4957. 12.Wang B, Wang Y, Wu Q, Huang HP*, Li S*. Effects of α2A Adrenoceptors on Norepinephrine Secretion from the Locus Coeruleus during Chronic Stress-Induced Depression. Frontiers in Neuroscience. 2017 May 1; 11: 243. 13.Li S*，Wang X, Ma QH, Yang WL, Zhang, XG, Dawe GS* and Xiao ZC*. Amyloid precursor protein modulates Nav1.6 sodium channel currents through a Go-coupled JNK pathway. Scientific Reports ,2016 Dec 23; 6:39320, DOI: 10.1038/srep39320 14.Lan YL#, Zhao J#, Ma TH*, Li S*. The potential roles of aquaporin 4 in Alzheimer's disease. MOLECULAR NEUROBIOLOGY. 2016 Oct; 53(8):5300-9. doi: 10.1007/ s12035-015-9446-1. 2016 Oct 53(8)：5300-9 15.Zhang XG#, Wang #, Zhou TT, Wu XF, PengY, Zhang WQ, Zhao J*, Li S*, Scorpion Venom Heat-Resistant Peptide Protects Transgenic Caenorhabditis elegans from β-Amyloid Toxicity. Front Pharmacol. 2016 Jul 26; 7: 227. 16.Chen JJ, Wang T, An CD, Jiang CY, Zhao J, Li S*. Brain-derived neurotrophic factor: a mediator of inflammation-associated. Rev Neurosci. 2016 Dec 1;27(8):793-811. 17.Wang X#, Zhang XG#, Zhou TT, Li, Jang CL, Xiao ZC, Ma QH, Li S*. Elevated Neuronal Excitability Due to Modulation of the Voltage-Gated Sodium Channel Nav1.6 by Aβ1-42. Frontiers in Neuroscience, 2016, published: 09 March 2016 doi: 10.3389/fnins.2016.00094 18.Lan YL, Zou S, Zhang C, Li J, Xu Y, Li S* Update on the effect of estradiol in postmenopause women with Alzheimer's disease: A systematic review. Acta Neurol Belg, 2016 Sep; 116(3): 249-57. 19.Lan YL#, Zou S#, Chen JJ, Zhao J*, Li S*. The neuroprotective effect of the association of aquaporin-4/glutamate transporter 1 (AQP4/GLT-1) against Alzheimer’s disease. Neural Plasticity. 2016 (2016), Article ID 4626593, 8 pages http://dx.doi.org/ 10.1155 /2016/ 4626593. 20.Lan YL, Zhao J, Ma TH*, Li S*. The research update on the potential roles of aquaporin 4 in neuroinflammation. Acta Neurol Belg, 2016 Jun;116(2):127-34 21.Yang JY*, Wei W, Liu JQ, Lan YL, Wang HB, Li S*. Role of bladder hydrodistention and intravesical sodium hyaluronate in the treatment of interstitial cystitis. Urology Journal. 2015,12(06): 2417-2421. 22.Lan YL#, Zhao J#, Ma TH*, Li S*. The great significance of research into the physiological relevance between AQP4 and vasopressin for studying Alzheimer's disease. J Alzheimers Dis Parkinsonism. 5: 192. doi:10.4172/2161- 0460.1000192 23.Cao Z, Wu XF, Peng Y, Zhang R, Li N, Yang JY, Zhang SQ, Zhang WQ, Zhao J*,Li S*. Scorpion Venom Heat-Resistant Peptide Attenuates Glial Fibrillary Acidic Protein Expression via c-Jun/AP-1. Cell Mol Neurobiol. 2015 Nov;35(8):1073-9. doi: 10.1007/s10571-015-0215-5. Epub 2015 Jul 2. 24.Yang JY*, Yang G, Ren J, Zhao J*, Li S*. Caffeine suppresses GABA receptor-mediated current of rat primary sensory neurons via inhibiting intracellular phosphodiesterase. Neurophysiology. April 2015, Volume 47, Issue 2, pp 108-114 25.Lan YL, Zhao J, Li S*. Update on the Neuroprotective Effect of Estrogen Receptor Alpha against Alzheimer ’s disease. J Alzheimer’s Dis. 2015; 43(4):1137-48.

1.《基础医学与临床》，主编：郭益民，朱亮，参编：李韶，人民卫生出版社，2017年，ISN 978-7-117-25095-5/R•25096 2.《Aquaporins》，Springer出版社，2017ISBN 978-94-024-1055-6. 2017. 主编：杨宝学。李韶参编 3.《痴呆的中西医治疗》，主编：乐卫东，陈立典，常务编委：李韶，科学出版社，2018年，ISBN 97-7-03-058682-7 4.《医学观念的更新与启示》，主编：李树壮，朱亮；作者：邵淑娟，付元山，张俊，李韶，朴花ᠦ୔