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吴成君

领域:生物产业 学校:大连理工大学职称:教授

头颈癌和女性宫颈癌发生相关的人乳头瘤病毒(HPV, Human Papilloma Virus)的细胞与分子生物研究。...

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教育背景

2005.9 2009.7 清华大学北京协和医学院 病原生物学 博士 2001.9 2004.7 中国农科院 生物工程 硕士 1997.9 2001.7 河北农业大学 生物技术 学士

工作经历

2019.3 至今 大连理工大学电信学部 2015.3 2019.2 瑞典隆德大学 科研教学 2010.7 2015.2 瑞典乌普萨拉大学 科研教学 2009.7 2010.6 中国科学院微生物所 科研 2004.7 2005.8 北京禹光生物公司 研发

项目课题经历

近几年做为子课题负责人主持瑞典国家级项目和省级项目三项。

论文、成果、著作等

近几年发表部分文章如下: 1. Chengjun Wu, Kersti Nilsson, Yunji Zheng, Camilla Ekenstierna, Natsuki Sugiyama, OlaForslund, Naoko Kajitani, Haoran Yu, Johan Wennerberg, Lars Ekblad, Stefan Schwarts. Short half-life of HPV16 E6 and E7 mRNAs sensitizes HPV16-positive tonsillar cancer cellsto DNA-damaging drugs. International Journal of Cancer 2019,144(4):297-310 IF: 7.36 2. Ola Forslund, Natsuki Sugiyama, Chengjun Wu, Naveen Ravi, Yuesheng Jin, Sabine Swoboda, Fredrik Andersson, Davit Bzhalava, Emilie Hultin, Kajsa Paulsson, Joakim Dillner, Stefan Schwartz, Johan Wennerberg, Lars Ekblad A novel human in vitro papillomavirus type 16 positive tonsil cancer cell line with high sensitivity to radiation and cisplatin BMC Cancer 2019 Mar 25;19(1):265. IF: 3.28 3. Kersti Nilsson#, Chengjun Wu# 1, Kajitani N., Glahder, J., Haoran Yu, Schwartz1, S.The DNA damage response can induce HPV16 late gene expression by inhibiting theHPV16 early polyadenylation signal and Activating HPV16 late splice sites Nuclear Acid Research 2018 Jun 1;46(10):5029-5049 (并列一作和通讯作者) IF: 11.56 4. Haoran Yu, Chengjun Wu*, Kersti Nilsson, Naoko Kajitani, Stefan Schwartz*Adenosine causes read-through into the late region of the HPV16 genome in a guanosine dependent manner Virology 2018 Jun 1;521:1-19. (共同通讯作者) IF: 3.37 5. Chengjun Wu, Kajitani N., Stefan Schwart Splicing and polyadenylation of human papillomavirus type 16 mRNAS. International Journal of Molecular Sciences 2017 Feb 9;18(2) IF: 3.68 6. Chengjun Wu, Xiaofang Cao, Di Yu, Elisabeth J. M. Huijbers, Magnus Essand, Göran Akusjärvi, Staffan Johansson, Cathrina Svensson HAdV-2 suppressed growth of SV40 T antigen transformed mouse mammary epithelial cell-induced tumours in SCID mice. Virology. 2015 18;489:44 IF: 3.37 7.Chengjun Wu, Lufeng Bai, Zhiqun Li, Charles E. Samuel, Göran Akusjärvi and Catharina Svensson Poor growth of human adenovirus-12 compared to adenovirus-2 correlates with a failure to impair PKR activation during the late phase of infection. Virology 2015 15;475:120-128. IF: 3.37 8. Li Guo*, Chengjun Wu*, Hongli Zhou, Chao Wu, Glaucia Paranhos-Bacala, Guy Vemet, Qi Jin, Jianwei Wang, Tao Hung Identification of DNA-binding protein (DBP), a nonstructural protein, as an immunogen with diagnostic potential in human. Co-first author Plos One 2013 8:e56708 IF: 3.53 9. Chengjun Wu, Daniel Öberg, Asif Rashid, Rajesh Gupta, StaffanJohansson, Göran Akusjärvi and Catharina Svensson A mouse mammary epithelial cell line permissive for highly efficient human adenovirus growth. Virology 2013 20:363-371 IF: 3.37 10. Chenjun Wu, Xiaobo Lei, Jianwei Wang, Tao Hung Generation of a replication deficient recombinant human adenovirus type 35 vector using bacterial-mediated homologous recombination J. Virol. Methods 2012(177): 55-63. IF: 1.91

专利、著作版权等

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