1997.09-2001.06 广州大学攻读生物科学学士学位 2002.09-2005.06 暨南大学攻读遗传学专业硕士学位 2005.09-2008.06 中山大学攻读生物化学与分子生物学专业博士学位

2009.04-至今 江苏大学生命科学研究院工作 2015.06-2018.09 江苏大学医学院临床医学博士后流动站开展研究工作 2017.04-2018.04 加州大学伯克利分校公共卫生学院高级访问学者 2013.09-2014.09 镇江市京口区政府经济信息与发展改革委员会挂职锻炼（副主任） 2009.07-2012.09 在江苏大学食品科学与工程博士后流动站开展研究工作 2008.06-2009.04 中国科学院上海生命科学研究院生化细胞所工作 2001.07-2002.09 广东Ⴕ୔

1.国家自然科学青年基金(31000080)：家蚕细小病毒样病毒DNA聚合酶的功能研究(2011.01-2013.12)主持、结题 2.江苏大学高级人才启动基金：(09JDG057)主持、结题 3.中国博士后二等资助(2011M500855)：家蚕核型多角体病毒Bm65和Bm91基因的功能研究(2011/11-2013/11),主持、结题 4.国家自然科学基金：家蚕二分浓核病毒非结构蛋白NS1蛋白的表达调控及靶分子识别(2013.01-2016.12)副主持人（排名第2）、结题 5.国家自然科学基金(31272507/C1703)：自编码DNA聚合酶的ssDNA病毒基因组复制模式(2013.01-2016.12)参与、结题（排名3/13）； 6.国家自然科学基金(30871826/C1703：家蚕浓核病毒中国株非结构蛋白特性和病毒复制原点分析 (2009.01-2011.12)参与、结题(排名2/5) 7.国家自然科学青年基金(31402016)：家蚕杆状病毒蛋白Bm65的核酸内切酶活性分析及在病毒与宿主抗紫外线辐射中的作用(2015.01-2017.12)副主持（排名第2）、结题 8.国家自然科学青年基金（81402840），干扰素对HBV应答的关键差异蛋白及其调控方式，(2015.01-2017.12)已结题，主要参与人（排名第3） 9.国家自然基金(30970612)：人聚合酶Polδ小亚基P12生化功能研究(2010.01-2012.12)参与、结题(排名4/5)； 10.江苏大学青年骨干教师培养工程资助(培育期：2014.01-2017.12) 11.江苏省政府和江苏大学联合资助公派留学：(2017.04-2018.04) 12.江苏大学青年科技扶持基金(FCJJ2015028)：(2015.10-2018.9)主持、结题 13.江苏省博士后基金(1501070C)：家蚕二分浓核病毒127K和53K蛋白的产生机制和功能研究(2015.08-2018.06)主持、结题.

【主要论著】 1.Qi Tang, Fangying Chen, Xinyu Qi, Peng Wu, Huiqin Chen, Lipeng Qiu, Zhaoyang Hu, Keping Chen, GuohuiLi*. Bombyx mori Rad23 (BmRad23) contributes to the repair of UV-damaged BmNPV. Pesticide Biochemistry and Physiology, Available online 2 January 2020. 2. Li D, Ramanathan S, Wang G, Wu Y, Tang Q, Li G*. Acetylation of lysine 7 of AhyI affects the biological function in Aeromonas hydrophila. Microb Pathog, 2020, 140:103952. 3. Guohui Li, Xinyu Qi, Huiqing Chen, Zhaoyang Hu, Fangying Chen, Liang Deng, Zhongjian Guo, Keping Chen and Qi Tang*. The Motif of 76KRKCSK in Bm65 Is an Efficient Nuclear Localization Signal Involved in Production of Infectious Virions. Front Microbiol, 2019, 10:2739 4. Li G, Qi X, Hu Z, Tang Q*. Mechanisms Mediating Nuclear Trafficking Involved in Viral Propagation by DNA Viruses. Viruses, 2019, 11(11). pii: E1035. 5. Tang Q, Chen F, Wu P, Qiu L, Chen H, Chen K, Li G*. BmNPV infection correlates with the enhancement of the resistance of Bombyx mori cells to UV radiation. Arch Insect Biochem Physiol, 2019, 102(1):e21598. 6. Tang Q, Qiu L, Li G*. Baculovirus-Encoded MicroRNAs: A Brief Overview and Future Prospects. Curr Microbiol, 2019, 76(6):738-743. 7. Zhaoyang Hu, Yanchun Deng, Xiaolong Zhang, Peipei Tang, Weijuan Sun, Guohui Li*, Qian Yu, Qin Yao. Selection and validation of reference genes for reverse transcription quantitative real-time PCR (RT-qPCR) in silkworm infected with Bombyx mori bidensovirus. Biologia, 2018, 73:897–906. 8. Qiu L, Wang T, Tang Q, Li G, Wu P, Chen K. Long Non-coding RNAs: Regulators of Viral Infection and the Interferon Antiviral Response. Front Microbiol, 2018, 9:1621. 9. Tang Q, Wu P, Chen H, Li G*. Pleiotropic roles of the ubiquitin-proteasome system during viral propagation. Life Sci, 2018, 207:350-354. 9 10. Qiu L, Tang Q, Li G, Chen K*. Long non-coding RNAs as biomarkers and therapeutic targets: Recent insights into hepatocellular carcinoma. Life Sci, 2017, 191:273-282. 11. Qi Tang, Peng Wu, Zhaoyang Hu,Yanhua Yang, Lipeng Qiu, Hanqing Liu, Shanying Zhu, Zhongjian Guo, Hengchuan Xia, Keping Chen*,Guohui Li*. Evidence for the role of BmNPV Bm65 protein in the repair of ultraviolet-induced DNA damage. J Invertebr Pathol, 2017 149:82-86. 12. Guohui Li, Qian Zhou, LipengQiu, Qin Yao, Keping Chen, Qi Tang*, Zhaoyang Hu*. Serine protease Bm-SP142 was differentially expressed in resistant and susceptible Bombyx mori strains, involving in the defence response to viral infection. PLoS One, 2017, 12(4):e0175518. 13. Guohui Li*, Mangmang Li, Wu Xu, Qian Zhou, Zhaoyang Hu, Qi Tang, Keping Chen, Qin Yao. Regulation of BmBDV NS1 by phosphorylation: impact of mutagenesis at consensus phosphorylation sites on ATPase activity and cytopathic effects. J Invertebr Pathol, 2016, 133:66-72. 14. Hu Z, Zhang X, Liu W, Zhou Q, Zhang Q, Li G, Yao Q.Genome segments accumulate with different frequencies in Bombyxmoribidensovirus. J Basic Microbiol, 2016, 56:1-6. 15. Tang Q, Hu Z, Yang Y, Wu H, Qiu L, Chen K, Li G*.Overexpression of Bm65 correlates with reduced susceptibility to inactivation by UV light. J Invertebr Pathol, 2015, 127:87-92. 16. Li G, Zhou Q, Hu Z, Wang P, Tang Q, Chen K, Yao Q. Determination of the proteins encoded by BmBDV VD1-ORF4 and their interacting proteins in BmBDV-infected midguts. Curr Microbiol, 2015, 70(4):623-629. 17. Li G, Li M, Wang P, Hu Z, Yao Q, Tang Q, Chen K. Characterization of recombinant expression of Bombyxmoribidensovirusns1 using a modified vector. Acta Biochim Pol, 2014, 61(4):787-794. 18. Tang Q, Li G, Yao Q, Chen L, Lv P, Lian C, Chen K.Bm91 is an envelope component of ODV but is dispensable for the propagation of Bombyxmorinucleopolyhedrovirus.J InvertebrPathol, 2013, 113(1):70-77. (Co-First) 19. Zhaoyang Hu, Guohui Li, Guangtian Li, Qin Yao, Keping Chen. Bombyxmoribidensovirus: The type species of the new genus Bidensovirus in the new family Bidnaviridae, Chinese Science Bulletin, 2013, 58(36)4528-4532 20. Li G, Hu Z, Guo X, Li G, Tang Q, Wang P, Chen K, Yao Q. Identification of Bombyxmoribidensovirus VD1-ORF4 reveals a novel protein associated with viral structural component.Curr Microbiol. 2013, 66(6):527-534. 21. Tang Q, Li G, Yao Q, Chen L, Feng F, Yuan Y, Chen K. Bm65 is essential for the propagation of Bombyx mori nucleopolyhedrovirus. Curr Microbiol, 2013, 66(1):22-29. 22. Li G, Tang Q, Chen H, Yao Q, Ning D, Chen K. Display of Bombyx mori nucleopolyhedrovirus GP64 on the Bacillus subtilis spore coat. CurrMicrobiol. 2011, 62(5):1368-1373. 23. Nan Wang, Cheng Chang, Qin Yao, Guohui Li, Lvgao Qin, Liang Chen, Keping Chen. Display of Bomyx mori alcohol dehydrogenases on the Bacillus subtilis spore surface to enhance enzymatic activity under adverse conditions. PLoS One, 2011. 6(6):e21454. 24. Li G, Chen H, Tang Q, Huang G, Deng R, Wang J, Wang X. Effect of ac68 knockout and lef3 leading sequence disruption on viral propagation.CurrMicrobiol, 2011, 62(1):191-197. 25. Huiqing Chen, Guohui Li, Guoping Huang, Keping Chen, Qin Yao, Zhongjian Guo. Characterization of ORF29 of Bombyx mori nucleopolyhedrovirus. Acta Virol, 2010, 54(4): 275-80. 26. Huang GP, Li GH, Chen HQ, He YQ, Yao Q, Chen KP. Proteomic analysis of 3T3-L1 predipocytes having a higher cell proliferation rate after treatment with low-molecular-weight silk fibroin peptides. Cell Prolif. 2010, 43:515-527. 27. Chen H, Li G, Huang G, Chen K, Yao Q, Guo Z. Characterization of ORF29 of Bombyx mori nucleopolyhedroviru. Acta Virol, 2010, 54(4):275-80. 28. Li G, Sun C, Zhang J, He Y, Chen H, Kong J, Huang G, Chen K, Yao Q. Characterization of Bombyx mori parvo-like virus non-structural protein NS1.Virus Genes, 2009, 39(3):396-402. 29. Li G, Wang J, Deng R, Wang X. Characterization of AcMNPV with a deletion of ac68 gene.Virus Genes, 2008, 37(1):119-127. 30. 李国辉, 李芒芒, 周倩, 胡朝阳, 唐琦, 姚勤. 利用优化改造的家蚕杆状病毒表达系统提高NS1表达产量. 生物工程学报, 2015, 31(4):591 −602 31. 李国辉, 周倩, 胡朝阳, 唐琦, 邱立鹏, 姚勤. 病毒非经典途径合成蛋白的分子机制. 生命科学, 2015, 27(4):1-8 32. 李国辉, 周倩, 胡朝阳, 唐琦, 邱立鹏, 姚勤. 果蝇先天免疫分子机制研究进展. 生命科学研究, 2015, 6(19):559-564 33. 李芒芒, 周倩, 王鹏, 李国辉*. 磷酸化病毒蛋白的生物学功能及形成机制. 微生物学通报, 2015, 42(6):1133−1140 34. 李国辉, 周倩, 徐五, 胡朝阳, 姚勤. 家蚕二分浓核病毒VD1-ORF4基因在两类表达系统中的表达分析. 生物技术, 2015, 25( 3):227-231 35. 李国辉, 王鹏, 李芒芒，徐五, 胡朝阳, 姚勤. 创建可视化的家蚕杆状病毒表达系统表达家蚕二分浓核病毒非结构蛋白NS1. 生物工程学报2014, 30(4): 625 – 635 36. 胡朝阳, 李国辉, 李光田, 姚勤, 陈克平. 家蚕二分浓核病毒综述,科学通报, 2013, 58(1):1-6 37. 李国辉, 胡朝阳, 唐琦, 王鹏. 细小病毒非结构蛋白NS1作用机制的研究进展. 蚕业科学，2012, 38(5):0919－0923 38. 唐琦, 邱立鹏, 李东, 吴鹏, 李国辉*. 杆状病毒表达载体的应用现状. 微生物学通报, 2018, 45(2):1-9 39. 唐琦, 周倩, 邱立鹏, 李东, 李国辉*. 丝氨酸蛋白酶先天免疫中的功能和作用机制. 蚕业科学, 2017, 43(3):0502-0508 40. 唐琦, 吴鹏, 李国辉*. 人巨细胞病毒HCMV编码miRNA功能及其作用机制. 中国生物化学与分子生物学学报, 2018, 34(7):706-712 41. 李国辉*, 李东, 祁馨宇, 邱立鹏, 唐琦. 细胞自噬及其功能调控的分子机制. 生命科学研究, 2019, 23(1)：46-53