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杨鲲

领域:生物产业 学校:江苏大学职称:教授

疼痛的神经生物学基础,疼痛治疗的转化医学。 运用神经电生理学、神经解剖学和行为学方法,结合笼锁递质、光遗传学方法、全息亚细 胞水平记录;以及利用近红外脉冲、热敏纳米材料等,围绕疼痛传递和调控的机制,探讨 疼痛治疗的新策略。...

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教育背景

1988-1994 中国人民解放军第四军医大学 (现空军军医大学) 本科生 (六年制) 1995-1997 第四军医大学硕士研究生(人体解剖与组织胚胎学) 1999-2003 第四军医大学博士研究生(人体解剖与组织胚胎学)

工作经历

职历 1997-1999 日本佐贺医科大学 (现佐贺大学医学部) 生理学系,外国人研究员 1999-2001 第四军医大学解剖学教研室,讲师 2001-2002 日本九州大学医学部生理学系,外国人研究员 2002-2003 日本佐贺医科大学,文部科学省教官 2005-2007 美国马里兰大学牙医学院,博士后 2008-2013 美国马里兰大学医学院博士后、Research Associate 2014- 江苏大学医学院,特聘教授 (校内)、教授,江苏特聘教授

项目课题经历

论文、成果、著作等

近年论文 [1] Shao C, Chen P, Chen Q, Zhao M, Zhang W-N, #Yang K. Mu opioid receptors inhibit GABA release from parvalbumin interneuron terminals onto CA1 pyramidal cells. Biochemical and Biophysical Research Communications, 2020, 522:1059-1062 (#, 通讯作者). [2] Liu Y, Yang XJ, Xia H, Tang C-M, #Yang K. GABA releases from parvalbumin-expressing and unspecific GABAergic neurons onto CA1 pyramidal cells are differentially modulated by presynaptic GABAB receptors in mouse hippocampus. Biochemical and Biophysical Research Communications, 2019, 520:449-452 (#, 通讯作者). [3] Chen Q, Shao C, Jiang P, #Yang K. Differential sensitivity of presynaptic and postsynaptic GABAB receptors in rat periaqueductal gray. NeuroReport, 2017, 28:1221-1224 (#, 通讯作 者). [4] Li G, Shao C, Chen Q, Wang Q, #Yang K. Accumulated GABA activates presynaptic GABAB receptors and inhibits both excitatory and inhibitory synaptic transmission in rat midbrain periaqueductal gray. NeuroReport, 2017, 28:250-256 (#, 通讯作者). [5] #Yang K. Regulation of excitability in tonic firing substantia gelatinosa neurons of the spinal cord by small-conductance Ca2+-activated K+ channels. Neuropharmacology, 2016, 105:15-24 (#, 通讯作者). [6] #Yang K. Postnatal excitability development and innervation by functional transient receptor potential vanilloid 1 (TRPV1) terminals in neurons of the rat spinal sacral dorsal commissural nucleus: an electrophysiological study. Molecular Neurobiology, 2016, 53:6033-6042 (#, 通 讯作者). [7] Li G, Liu Z-L, Zhang W-N, #Yang K. Blockade of presynaptic 4-aminopyridine-sensitive potassium channels increases initial neurotransmitter release probability, reinstates synaptic transmission altered by GABAB receptor activation in rat midbrain periaqueductal gray. NeuroReport, 2016, 27:50-55 (#, 通讯作者). [8] #Yang K, Ma R, Wang Q, Jiang P, Li Y-Q. Optoactivation of parvalbumin neurons in the spinal dorsal horn evokes GABA release that is regulated by presynaptic GABAB receptors. Neuroscience Letters, 2015, 594:55-59 (#, 通讯作者).

专利、著作版权等

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