2008/09 至 2011/12 南开大学 生科院 生物材料 博士

2016/11 至今 耶鲁大学医学院 访问副教授 2015/05 至今 江苏大学医学院 副教授 2014/09 至今 江苏大学医学院 硕士生导师 2012/04 至 2015/05 江苏大学医学院 讲师

基 金 9. 镇江市重点研发计划（社会发展）。基于贻贝生物黏附与金属有机框架仿生构建胃滞留型多药物微载体。项目批准号：SH2019002. 金额: 15 万. 2019/06-2021/05，主持人。 8. 江苏省卫生计生委‘科教强卫工程’青年医学重点人才。构建铋掺杂型碳纳米颗粒应用于多模态影像引导下的肿瘤放射治疗. 项目批准号： QNRC2016444. 金额: 2 万. 2016/01/01-2020/12/31，主持人。 7. 江苏省委组织部“六大人才高峰”高层次人才项目。诊疗型碳量子点的构建及其在多模态影像引导放射治疗中的应用研究，2017/10-2019/10. 项目 批准号：WSN-281.金额：4 万. 主持人。 6. 江苏省教育厅“333 高层次人才培养工程” 科研项目资助计划。基于CBT-Cys 点击化学酶促聚合型多功能碳量子点的构建及应用， 2017/07 至 2019/07. 项目批准号：BRA2017145. 金额：3 万. 主持人。 5. 镇江市天益生物科技有限公司技术开发项目。磁控纳米制剂在靶向治疗中的应用及产品开发。2016/11/10-2018/10/09。10 万。主持人。 4. 国家自然基金青年项目。多功能聚胺基碳量子点的制备及其应用于 siRNA 基因转运和示踪成像的研究。起止时间：2014/01-2016/12。金额：24 万。项目批准号：81301316。主持人。 3. 中国博士后科学基金特别资助项目。MRI-荧光钆掺杂型碳量子点在肝癌早期诊疗中的应用。起止时间：2014/01-2016/12 金额：15 万。项目批准号：2014T70486。主持人。 2. 中国博士后科学基金面上项目一等。多功能聚氨基碳量子点的制备及其生物医学的应用研究。金额：8 万（一等）。起止时间：2014/01-2015/12。项目批准号：2013M540425。主持人。 1. 江苏大学高级专业人才科研启动基金。VEGF 控释梯度纳米纤维支架在血管组织工程中的应用研究。2013/01-2014/12，金额：5 万。项目批准号： 13JDG022。主持人。

第一作者或通讯作者： 19. Lirong Zhang, Dongyan Chen, Jingjing Zhang, Rong Cai, Lixia Xu, Nianhui Yu, Shuyu Zhang, Hao Yan, Jingzhou Jiang, Fengyi Du*, Aihua Gong*, A novel cholchicine/gadolinium-loading tubulin self-assembly nanocarrier for MR imaging and chemotherapy of glioma.Nanotechnology. 2020, 已接收。(通讯作者) 18. Zou S, Guo F, Wu L, Ju H, Sun M, Cai R, Xu L, Gong Y, Gong A, Zhang M, Du F*. One-pot synthesis of cerium and praseodymium co-doped carbon quantum dots as enhanced antioxidant for hydroxyl radical scavenging. Nanotechnology. 2020 Apr 17;31(16):165101. (通讯作者) 17. Zhang M, Zhao L, Du F, Wu Y, Cai R, Xu L, Jin H, Zou S, Gong A, Du F*. Facile synthesis of Cerium-doped Carbon Quantum Dots as highly efficient antioxidant for Free Radical Scavenging. Nanotechnology. 2019 Mar 25;30(32):325101. (通讯作者) 16. Yu M, Niu Y, Zhou D, Jiang R, Zhang L, Ju H, Gong A, Zou S, Zhang M, Du F*. Hyaluronic acid-functionalized gadolinium doped iron oxide nanoparticles for atherosclerosis-targeted MR imaging. Journal of biomedical nanotechnology. 2019 Jan 1;15(1):127-137. (通讯作者) 15. Du F, Wu Y, Du F, Zhang L, Feng W, Zhao L, Cai R, Xu L, Bian G, Li J, Zou S, Gong A, Zhang M. Construction of catechol-grafted chitosan alginate/barium sulfate microcapsules for computed tomography real-time imaging and gastroretentive drug delivery. Int J Nanomedicine. 2019 Jul 31;14:6001-6018. doi: 10.2147/IJN.S204237. 14. Fang Z, Jiang R, Zhang L, Wu Y, Zhao X, Zhao L, Li J, Zou S, Zhang M, Du F*. In situ fabrication of radiopaque microcapsules for oral delivery and real-time gastrointestinal tracking of Bifidobacterium. Int J Nanomedicine. 2018; 2018 Jul 12;13:4093-4105. (通讯作者) 13. Zou S, Zhu X, Zhang L, Guo F, Zhang M, Tan Y, Gong A, Fang Z, Ju H, Wu C, Du F*. Biomineralization-Inspired Synthesis of Cerium-doped Carbonaceous Nanoparticles for Highly Hydroxyl Radical Scavenging Activity. Nanoscale Research Letters. 2018 Mar 6;13(1):76. (通讯作者) 12. Du F, Zhang L, Zhang L, Zhang M, Gong A, Tan Y, Miao J, Gong Y, Sun M, Ju H, Wu C, Zou S*. Engineered gadolinium-doped carbon dots for magnetic resonance imaging-guided radiotherapy of tumors. Biomaterials, 2017. 121.109-120. ( 一 区 ， IF=8.8). 11. Du F, Lou J, Jiang R, Fang Z, Zhao X, Niu Y, Zou S, Zhang M, Gong A, Wu C. Hyaluronic acid-functionalized bismuth oxide nanoparticles for computed tomography imaging-guided radiotherapy of tumor. Int J Nanomedicine. 2017; 12: 5973-5992. 10. M. Zhang, X. Zhao, Z. Fang, Y. Niu, J. Lou, Y. Wu, S. Zou, S. Xia, M. Sun, F. Du*, Fabrication of HA/PEI-functionalized carbon dots for tumor targeting, intracellular imaging and gene delivery. RSC Adv., 2017. 7. 3369-3375. (通讯作者) 9. M. Zhang, Z. Fang, X. Zhao, Y. Niu, J. Lou, L. Zhao, Y. Wu, S. Zou, Q. Shao, F. Du*. Hyaluronic acid functionalized Nitrogen-doped carbon quantum dots for targeted specific bioimaging. RSC Adv., 2016, 6, 104979-104984. (通讯作者) 8. Du F, Li J, Hua Y, Zhang M, Zhou Z, Yuan J, Wang J, Peng W, Zhang L, Xia S, Wang D, Yang S, Xu W, Gong A, Shao Q*. Multicolor nitrogen-doped carbon dots for live cell imaging. Journal of biomedical nanotechnology. 2015. 11, 780-788. Cited by 18. 7. Zhang M, Ju H, Zhang L, Sun M, Zhou Z, Dai Z, Zhang L, Gong A, Wu C, Du F*. Engineering iodine-doped carbon dots as dual-modal probes for fluorescence and X-ray CT imaging. International journal of nanomedicine. 2015. 10:6943-53. (通讯作者) 6. Du F, Zhang M, Li X, Li J, Jiang X, Li Z, Hua Y, Shao G, Jin J, Shao Q, Zhou M, Gong A*. Economical and green synthesis of bagasse-derived fluorescent carbon dots for biomedical applications. Nanotechnology. 2014 Aug 8: 25(31): 315702. Cited by 22. 5. Fengyi Du, Xin Jin, Junhui Chen, Ye Hua, Mulan Cao, Lirong Zhang, Jianan Li, Li Zhang, Jie Jin, Chaoyang Wu, Aihua Gong, Wenrong Xu, Qixiang Shao, Miaomiao Zhang*, Nitrogen-doped carbon dots as multifunctional fluorescent probes. Journal of Nanoparticle Research. 2014 November 05, 16: 2720. Cited by 9. 4. Fengyi Du, Jing Yuan, Miaomiao Zhang, Jianan Li, Zhou zhou, Zhang Li, Mulan Cao, Wanxin Peng, Junhui Chen, Aihua Gong, Wenrong Xu, Qixiang Shao*. Facile Synthesis of Biocompatible Nitrogen-doped Carbon Dots for Bioimaging. RSC advance. 2014 Aug 11, 4 (71), 37536-37541. Cited by 15. 3. Du F, Wang H, Zhao W, Li D, Kong D, Yang J, Zhang Y. Gradient nanofibrous chitosan/poly ɛ-caprolactone scaffolds as extracellular microenvironments for vascular tissue engineering, Biomaterials, 2012. 33(3), 762-770. (一区，IF=8.8). 2. Du F, Zhao W, Zhang M, Mao H, Kong D, Yang J*, The synergistic effect of aligned nanofiber and hyaluronic acid coating on endothelial cell behavior for vascular tissue engineering, Journal of Nanoscience and Nanotechnology, 2011. 11(8), 6718-6725. Cited by 12. 1. Niu G, Fengyi Du, Song L, Zhang H, Yang Y, Cao H, Zheng Y, Yang Z, Wang G, Yang H, Zhu S*. Synthesis and characterization of reactive poloxamer 407s for biomedical applications, J Control Releas, 2009. 138 (1):49-56. (The first co-author) 其他论文(非第一或通讯作者)： 13. Ma J, Zhang S, Liu J, Liu F, Du F, Li M, Chen AT, Bao Y, Suh HW, Avery J, Deng G, Zhou Y, Wu P, Sheth K, Wang H, Zhou J. Targeted Drug Delivery to Stroke via Chemotactic Recruitment of Nanoparticles Coated with Membrane of Engineered Neural Stem Cells. Small. 2019 Aug;15(35): e1902011. doi: 10.1002/smll.201902011. Epub 2019 Jul 10. 12. Deng G, Ma C, Zhao H, Zhang S, Liu J, Liu F, Chen Z, Chen AT, Yang X, Avery J, Zou P, Du F, Lim KP, Holden D, Li S, Carson RE, Huang Y, Chen Q, Kimberly WT, Simard JM, Sheth KN, Zhou J. Anti-edema and antioxidant combination therapy for ischemic stroke via glyburide-loaded betulinic acid nanoparticles. Theranostics. 2019 Sep 21; 9 (23) :6991-7002. 11. Guo X, Deng G, Liu J, Zou P, Du F, Liu F, Chen AT, Hu R, Li M, Zhang S, Tang Z, Han L, Liu J, Sheth KN, Chen Q, Gou X, Zhou J. Thrombin-Responsive, Brain-Targeting Nanoparticles for Improved Stroke Therapy. ACS Nano. 2018 Aug 28;12(8): 8723- 8732. 10. Yu X, Gou X, Wu P, Han L, Tian D, Du F, Chen Z, Liu F, Deng G, Chen AT, Ma C, Liu J, Hashmi SM, Guo X, Wang X, Zhao H, Liu X, Zhu X, Sheth K, Chen Q, Fan L, Zhou J. Activatable Protein Nanoparticles for Targeted Delivery of Therapeutic Peptides. Adv Mater. 2018 Feb;30(7). doi: 10.1002/adma.201705383. 9. Xu M, Bian S, Li J, He J, Chen H, Ge L, Jiao Z, Zhang Y, Peng W, Du F, Mo Y, Gong A*. MeCP2 suppresses LIN28A expression via binding to its methylated-CpG islands in pancreatic cancer cells. Oncotarget. 2016 Feb 19. doi: 10.18632/oncotarget. 7507. 8. Wang J, Zhuo Y, Yin L, Wang H, Jiang Y, Liu X, Zhang M, Du F, Xia S, Shao Q*. Doxycycline Protects Thymic Epithelial Cells from Mitomycin C-Mediated Apoptosis In Vitro via Trx2-NF-x03BA;B-Bcl-2/Bax Axis. Cell Physiol Biochem. 2016; 38 (2):449-60. 7. Peng W, DU T, Zhang Z, Du F, Jin J, Gong A*. Knockdown of autophagy-related gene LC3 enhances the sensitivity of HepG2 cells to epirubicin. Exp Ther Med. 2015. 9(4):1271-1276. 6. Liu X, Zhao Q, Peng X, Xia S, Shen W, Zong Y, Cheng J, Wu W, Zhang M, Fengyi Du, Xu W, Qian H, Shao Q*. PTD-mediated intracellular delivery of mutant NFAT minimum DNA binding domain inhibited the proliferation of T cells. Int Immunopharmacol. 2014. 19(1):110-8. 5. Jiang X, Xin H, Gu J, Fengyi Du, Feng C, Xie Y, Fang X*. Enhanced Antitumor Efficacy by d-Glucosamine-Functionalized and Paclitaxel-Loaded Poly(Ethylene Glycol)–Co–Poly (Trimethylene Carbonate) Polymer Nanoparticles. J Pharm Sci. 2014. 11. 4. Jiang Xinyi, Xin Hongliang, Ren Qiuyue, Gu Jijin, Zhu Lingjun, Du Fengyi, Feng Chunlai, Xie, Yike, Sha Xianyi, Fang Xiaoling*. Nanoparticles of 2-deoxy-D- glucose functionalized poly(ethylene glycol)–co–poly (trimethylene carbonate) for dual- targeted drug delivery in glioma treatment. Biomaterials, 2014. 35 (1):518-529. 3. Long L, Zhou L, Wang L, Meng S, Gong A, Fengyi Du, Zhang C.A*. Coumarin-based fluorescent probe for biological thiols and its application for living cell imaging. Org Biomol Chem. 2013. 21;11(47):8214-20. 2. Long Lingliang, Zhou Liping, Wang Lin, Meng Suci, Gong Aihua, Fengyi Du, Zhang Chi*. A highly selective and sensitive fluorescence ratiometric probe for cyanide and its application for the detection of cyanide in natural water and biological samples. Analytical Methods. 2013; 5:(23): 6605-6610. 1. Yu M, Fengyi Du, Ise H, Zhao W, Zhang Y, Yu Y, Yao F, Yang J, Akaike T*, Preparation and characterization of a VEGF-Fc fusion protein matrix for enhancing HUVEC growth. Biotechnol Lett, 2012. 34(9):1765-71. (The first co-author) 著 作 1. Du F, Zhou J, Vascular intervention: from angioplasty to bioresorbable vascular scaffold, Molecular, Cellular and Tissue Engineering of the Vascular System, Springer Press, 2018. 1097: 181-189. DOI: 10.1007/978-3-319-96445-4_9

专 利 7. 发明人：杜凤移，赵璐璐，杜凤亭，张苗苗，蔡茸，邹圣强，吴云超。发明名称: 一种抗氧化铈掺杂碳量子点及其制备方法与应用。申请号： CN201910179616.2。 6. 发明人：杜凤移，吴云超，杜凤亭，张苗苗，李建刚，边高瑞，发明名称: 一种 CT 可视化与黏膜粘附型双功能微胶囊及其制备方法。申请号： CN201910158603.7。 5. 发明人：杜凤移，居会祥，孙明忠，张苗苗，张丽，房正邹，赵雪芬。发明名称：一种荧光-CT 双模态影像探针及其制备方法。授权专利号： ZL 2015 1 0062498.9。授权时间：2018.1.16 4. 发明人：杜凤移，张丽，张礼荣，张苗苗，华晔，龚爱华，邵启祥。发明名称：一种基于碳量子点的荧光-MRI 双模态影像探针的制备方法及其应用。授权专利号：ZL 2014 1 0393974. 0。授权时间：2017.3.1 3. 发明人: 杜凤移，张苗苗，邵启祥，夏圣，许化溪，许文荣，钱晖，刘霞。发明名称： 一 种高荧光性能碳量子点的制备方法。 申请号： CN201310168911。 2. 发明人：张苗苗，杜凤移，龚爱华，邵启祥，邵根宝，彭琬昕，金洁，吴 卫疆，周洲，袁婧。发明名称：一种环保经济型荧光碳量子点的制备方法 申请号：CN201310225051。 1. 发明人：杨军，于美华，杜凤移，发明名称: 一种内皮细胞生长因子融合 蛋白及其在再生医学中的应用。申请号：CN201110202533。