1981年长江大学（原湖北荆州师范学院）化学系毕业；1982年在华南师范大学进修一年；1988年武汉大学化学系高分子专业研究生毕业，获理学硕士学位；2006年南开大学高分子化学与物理研究所博士毕业，获理学博士学位

多年在原湖北荆州师范学院（现并为长江大学）任教

1、 复合改性壳聚糖术后防粘剂的制备及产业化研究。（江苏省工业支撑计划，主持人）； 2、海藻酸钠改性螯合絮凝剂的合成及其对工业污水的治理。（国家重点实验室项目，主持人）； 3、刺激响应性聚两性离子纳米颗粒的创制及性能研究, (江苏省基础研究计划，主持）； 4、超声、臭氧、紫外协同处理废水的机理与参数优化研究。（NSFC项目，主要参与） 5、医用防粘剂及医用水凝胶创伤敷料研制及产业化，（江苏康普生物医药科技有限公司项目，主持人） 6、关于民用工业应对质疑性视察的前期工作研究。（工信部项目，主持人）

[1] LipingZhang, Luyan Wu, Yuanlong Cao, Yunan Wu, Jing Chen & Caihua Ni. Studies on preparations and pH/redoxresponsiveness of zwitterionic nanomicelles of poly[lysine-co-N,N-bis(acryloyl)cystamine-co-dodecylamine]. International Journal of Polymeric Materials and Polymeric Biomaterials. 2018, 67(8)，528-534. [2] Liping Zhang,Luyan Wu, Gang Shi, Xinxin Sang & Caihua Ni，Studies on the preparation and controlled release of redox/pH-responsive zwitterionic nanoparticles based on poly-L-glutamic acid and cystamine, Journal of Biomaterials Science, Polymer Edition. 2018. 29(6), 646-662. [3] Liping Zhang, Ming Liu, Tian Qi, Haili Zhou & Caihua Ni. Preparations and properties of drug-eluting embolization microspheres based on modified gelatin, Soft Materials, 2018. 16(2) 117–125 [4] Zhenle Tian, Liping Zhang, Gang Shi, Xinxin Sang, Caihua Ni. The synthesis of modified alginate flocculants and their properties for removing heavy metal ions of wastewater. Journal of Applied Polymer Science.2018,135, 46577 [5] Xinxin Sang, Qiyi Yang, Gang Shi, Liping Zhang, Dawei Wang, Caihua Ni，preparation of pH/redox dual responsive polymeric micelles with enhanced stability and drug controlled release.Materials Science & Engineering C. 2018, 91, 727–733 [6]Yuanyuan Ding, Liping Zhang, Gang Shi, Xinxin Sang, Caihua Ni. Preparations and doxorubicin controlled release of amino-acid based redox/pH dual-responsive nanomicelles. Materials Science and Engineering C 77 (2017) 920–926 [7] Liping Zhang, Yamin Zhou, Gang Shi, Xinxin Sang, Caihua Ni. Preparations of hyperbranched polymer nano micelles and the pH/redox controlled drug release behaviors. Materials Science and Engineering C. 79 (2017) 116–122 [8] L. Wu, C. Ni, L. Zhang, G. Shi, X. Bai, Y. Zhou, F. He. Surface Charge Convertible and Biodegradable Synthetic Zwitterionic Nanoparticles for Enhancing Cellular Drug Uptake. Macromolecular Bioscience, 2016, 16, 308-313. [9] LuyanWu, Liping Zhang, Gang Shi, Caihua Ni. Zwitterionic pH/redox nanoparticles based on dextran as drug carriers for enhancing tumor intercellular uptake of doxorubicin. Materials Science and Engineering C 2016, 61, 278–285 [10] Liping Zhang, Jie Wang, Caihua Ni, Yanan Zhang, Gang Shi. Preparation of polyelectrolyte complex nanoparticles of chitosan and poly(2-acry1amido- 2-methylpropanesulfonic acid) for doxorubicin release. Materials Science and Engineering C 2016, 58, 724–729 [11]Luyan Wu, Caihua Ni, Liping Zhang & Gang Shi.Preparation of pH-sensitive zwitterionic nano micelles and drug controlled release for enhancing cellular uptake. Journal of Biomaterials Science, Polymer Edition.2016, 27 (7), 643–656. [12] Yanan Zhang, Caihua Ni, Gang Shi, Jie Wang, Meng Zhang, Wang Li. The polyion complex nano-prodrug of doxorubicin (DOX) with poly(lactic acid-co-malic acid)-block-polyethylene glycol: preparation and drug controlled release.Med. Chem. Res. 2015, 24, 1189-1195. [13] Caihua Ni, Ronghui Lu，Lei Tao,Gang Shi.Xuejun Li, Changhu Qin. Synthesis of poly(vinyl alcohol-graft-lactic acid) copolymer and its application as medical anti-tissue adhesion thin film. Polym. Bull. 2015, 72:1515–1529 [14] Gang Shi, Yuanyuan Ding, Xin Zhang, Luyan Wu, Fei He Caihua Ni. Drug release behavior of poly (lacticglycolic acid) grafting from sodium alginate (ALG-g-PLGA) prepared by direct polycondensation. Journal of Biomaterials Science, Polymer Edition, 2015,26(16), 1152-1162 [15]Hong Cai, Caihua Ni, Liping Zhang. Preparation of complex nano-particles based on alginic acid/poly[(2-dimethylamino) ethyl methacrylate] and a drug vehicle for doxorubicin release controlled by ionic strength. European Journal of Pharmaceutical Sciences 2012, 45, 43–49 [16] Caihua Ni, Geng Wu, Changping Zhu, and Bolong Yao. The Preparation and Characterization of Amphiphilic Star Block Copolymer Nano Micelles Using Silsesquioxane As the Core. J. Phys. Chem. C 2010, 114, 13471–13476

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