1998.9-2002.6 安徽科技学院，食品科学与工程专业工科学士 2002.9-2008.6 江南大学，发酵工程专业，工学博士

2008.7-2011.5 江南大学，生物工程学院 讲师 2011.5-2018.5 江南大学，生物工程学院 副教授 2018.5-- 江南大学，生物工程学院 教授 其中： 2011.3-2012.3 南非德班理工大学，应用科学系，博士后 2015.12-2016.12 吐鲁番市委农办（政研室）副主任 中组部第十六批博士服务团

1、面向新工科的生物工程专业实践教育体系构建，教育部新工科研究与实践项目，2017，排名 4/22 2、生物工程专业“靶向人才”分类培养体系构建与实践，江苏省教改重点项目，2017，排名7/14 3、国家自然科学基金：大肠杆菌莽草酸代谢途径的理性设计和构建及其代谢机制研 究.(21006039； 2011.01-2013.12) 主持 4、江苏省自然科学基金 面上项目 （2017-2020）主持 5、教育部自主科研重点项目（2016-2018）主持 6、教育部留学回国人员科研启动费 （2013-2015） 主持 7、 江苏省科技支撑计划：面包抗老化剂替代品--生麦芽糖α-淀粉酶高效制备关键技术主持 8、 企业横向课题 赢创德固赛 （2013-2018）主持

1. Chen X, Zhou J, Zhang L, Pu Z, Liu L, Shen W, Fan Y. Development of an Escherichia coli-based biocatalytic system for the efficient synthesis of N-acetyl-D-neuraminic acid. Metab Eng. 2018, 47: 374382. 2. Xue Y, Chen X, Yang C, Chang J, Shen W, Fan, Y. Engineering Eschericha coli for Enhanced Tyrosol Production. J Agric Food Chem, 2017, 65(23): 4708-4714 3. Chen XZ. Yeast cell surface display: An efficient strategy for improvement of bioethanol fermentation performance. Bioengineered, 2017, 8(2): 115-119. 4. Chen XZ, Xiao Y, Shen W, Algasan G, Zhang L, Fan Y, Wang ZX. Display of phytase on the cell surface of Saccharomyces cerevisiae to degrade phytate phosphorus and improve bioethanol production. Applied Microbiology Biotechnology, 2016, 100(5): 2449-2458. 5. Zhang Lihu, Chen Xianzhong, Chen Zhen, Wang Zezheng, Jiang Shan, Li Li, Markus Pötter, Shen Wei, Fan You. Development of an efficient genetic manipulation strategy for sequential gene disruption and expression of different heterologous GFP genes in Candida tropicalis. Applied Microbiology Biotechnology, 2016, 100(22): 9567-9580. 6. Zhou Junbo, Chen Xianzhong, Lu Liping, Govender Algasan, Yang Haiquan, Shen Wei. Enhanced production of N-acetyl-d-neuraminic acid by whole-cell bio-catalysis of Escherichia coli. Journal of Molecular Catalysis B: Enzymatic, 2016, 125: 42–48. 7. Guo Wenwen, Yang Haiquan. Qiang Shumin. Fan You. Shen Wei, Chen Xianzhong. Overproduction, purification, and property analysis of an extracellular recombinant fructosyltransferase. European Food Research and Technology, 2016, 242(7): 1159–1168 8. Ma Y, Shen W, Chen X, Liu L, Zhou Z, Xu F, Yang H. Significantly enhancing recombinant alkaline amylase production in Bacillus subtilis by integration of a novel mutagenesis-screening strategy with systems-level fermentation optimization. Journal of Biological Engineering, 2016, 10(1):13. 9. Ma Y, Yang H, Chen X, Sun Bo, Du G, Zhou Z, Song J, Fan Y, Shen W. Significantly improving the yield of recombinant proteins in Bacillus subtilis by a novel powerful mutagenesis tool (ARTP): Alkaline α-amylase as a case study. Protein expression and purification, 2015, 114: 82-88. 10. Chen XZ, Tian KM, Niu DD, Shen W, Algasan G, Singh S, Wang ZX. Efficient bioconversion of crude glycerol from biodiesel to optically pure D-lactate by metabolically engineered Escherichia coli. Green Chem. 2014;16(1):342-50. 11. Chen XZ, Li MM, Zhou L, Shen W, Algasan G, Fan Y et al. Metabolic engineering of Escherichiacoli for improving shikimate synthesis from glucose. Bioresource Technol. 2014;166:64-71. 12. Chen XZ, Xia Y, Shen W, Fan Y, Govender A, Wang ZX. Engineering glycolysis branch pathways of Escherichia coli to improve heterologous protein expression. Process Biochem. 2014;49(12):2063-70. 13. Yang HQ, Ma YF, Wang YT, Yang HX, Shen W, Chen XZ. Transcription regulation mechanisms of bacteriophages Recent advances and future prospects. Bioengineered. 2014;5(5):300-4. 14. Chen XZ, Zhou L, Tian KM, Kumar A, Singh S, Prior BA, Wang ZX. Metabolic engineering of Escherichia coli: A sustainable industrial platform for bio-based chemical production. Biotechnol Adv. 2013;31(8):1200-23. 15. Chen XZ, Fang HY, Zhuge, B, Wang ZX, Govender A, Zhuge J. Heterologous expression of the osmotolerant yeast Candida glycerolgenesis glycerol-3-phosphate dehydrogenase gene (CgGPD) in Saccharomyces cerevisiae lacking the HOG pathway. Process Biochem. 2013;48(10):1469-75. 16. Zhou L, Niu DD, Tian KM, Chen XZ, Prior BA, Shen W et al. Genetically switched D-lactate production in Escherichia coli. Metab Eng. 2012;14(5):560-8. 17. Huang Wen-Jing, Zuo Zhi-Rui, Shen Wei, Singh Suren, Chen Xianzhong, Fan You, WangZhengXiang. High-level expression of alkaline protease using recombinant Bacillus amyloliquefaciens. African Journal of Biotechnology. 2012;11(14): 3358-3362. 18. Tian Kangming, Chen Xianzhong, Shen Wei, Prior Bernard A, Shi Guiyang, Singh Suren, Wang Zhengxiang. High-efficiency conversion of glycerol to D-lactic acid with metabolically engineered Escherichia coli. African Journal of Biotechnology, 2012; 11(21): 4860-4867. 19. Zhou L, Zuo ZR, Chen XZ, Niu DD, Tian KM, Prior BA et al. Evaluation of genetic manipulation strategies on D-lactate production by Escherichia coli. Curr Microbiol. 2011; 62(3): 981-9.20. Li S, Shen W, Chen XZ, Shi GY, Wang ZX. Secretory expression of Rhizopus oryzae alpha-amylase in Kluyveromyces lactis. Afr J Biotechnol. 2011;10(20):4190-6. 21. Chen XZ, Fang HY, Rao ZM, Shen W, Zhuge B, Wang ZX et al. Comparative characterization of genes encoding glycerol 3-phosphate dehydrogenase from Candida glycerinogenes and Saccharomyces cerevisiae. Prog Biochem Biophys. 2009;36(2):198-205. 22. Chen XZ, Fang HY, Rao ZM, Shen W, Zhuge B, Wang ZX et al. An efficient genetic transformation method for glycerol producer Candida glycerinogenes. Microbiol Res. 2008;163(5):531-7. 23. Chen XZ, Fang HY, Rao ZM, Shen W, Zhuge B, Wang ZX et al. Cloning and characterization of a NAD+-dependent glycerol-3-phosphate dehydrogenase gene from Candida glycerinogenes, an industrial

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