1994-1995， 美国约翰霍普金斯大学分子流行病学，博士后； 1990-1994， 美国波士顿大学医学院，病理与免疫学专业，博士； 1978-1981， 上海第一医学院预防医学系，营养与食品卫生专业，硕士； 1975-1978, 上海第一医学院预防医学系，本科。

2008年至今，美国乔治亚大学公共卫生学院环境健康科学系，教授，系主任； 2006-2008，美国德州理工大学环境毒理系，教授； 2006-2008，美国德州理工大学环境和人类健康研究所，人类健康部主任 2006-2008，美国德州理工大学西南癌症研究中心，癌症预防项目主管 2000-2005，美国德州理工大学环境毒理系，副教授 1997-2000，美国约翰霍普金斯大学公共卫生学院环境健康科学系，研究助理教授； 1994-1996，美国约翰霍普金斯大学公共卫生学院环境健康科学系，资深副研究员 Ⴕ୔

CURRENT FUNDED RESEARCH GRANTS 1. 1 RO1 CA 90997-05 Wang (PI) 06/16/03 – 05/31/09 NCI/NIH $1,834,573/whole project Chemoprevention of green tea polyphenols on liver cancer The major goal of this project is to study chemopreventive effect of green tea polyphenols on reducing various carcinogen biomarkers and incidence of primary liver cancer in a 5-year clinical trial in 1,800 high-risk people. 2. ECG-A-00-07-00001-00 Wang (PI) 01/01/2008-12/31/2012 USAID/Peanut CRSP $990,000 Development of methods for establishing a global network for aflatoxin exposure The major goal of this project is to develop analytical method for measurement of blood samples collected from world-wide and to establish a global aflatoxin exposure network using biomarker as approach. 3. W911SR-04-C0050 Wang (PI) 10/01/2000 – 8/12/2008 RDECOM, US Army Combinative Toxicity Studies of Biotoxin Mixtures The major goal of this research contract is to study acute toxicity of various biotoxin mixtures in rats and fish model and to develop method to detect these biotoxin mixtures in environmental samples and biological fluids. 4. 1R21AT003735-01A1 (Shen) 09/01/2007-08/31/2009 NCCAM/NIH $572,720/whole period GTP and Tai Chi for Bone Health: a Pilot Study The major goal of this project is to conduct a clinical trial for assessing Tai Chi and green tea polyphenols in enhance bone health in women. Role: TTU-PI RESEARCH GRANTS (PENDING or SUBMITTED) 1. 1RO1AT004655-01A Wang (PI) 06/01/2009 – 05/31/2014 $1,830,931/whole period Molecular Basis of Individual Response to Green Tea Polyphenols The major goal of this research grant is to use Omics tool to study molecular basis of individual responses to green tea polyphenols through use of samples collected from previous clinical trial. 2. 1RO1ES016744-01A Wang (PI) 07/01/2009-06/30/2014 NIEHS $1,831,250/whole project Molecular Biomarkers of Human Mycotoxicoses The major goal of this research proposal is to validate and refine panels of biological response indicators representing exposure to foodborne mycotoxins such as aflatoxins and fumonisins and predicting the pathogenesis of human mycotoxicoses in high-risk populations. COMPLETED AND PARTICIPATED RESEARCH GRANTS (in USA only) 1. Trichothecene Mycotoxin Studies, 1983-1987, United States Army Medical Research and Development Command (Contract No. DAMD17-85-C-5208); 2. Studies of Fossil Fuel Combustion Products, 1988-1993 NIEHS (Grant No. P01-ES01640); 3. Mechanisms of Regulation of Actin-based Microfilaments, 1991-1995, NIGMS (Grant No. GM37590); 4. Neutrophil Studies, 1986-1991, NHLBI (Grant No.HL 33565); 5. Training Program in Environmental Health Sciences, 1994, NIEHS (Grant No. ES07141); 6. Molecular Biomarkers For Environmental Carcinogens, 1993-1997; 1997-2002, NIEHS P01 ES06052. Role: Co-investigator 7. DAAD13-00-C-0056 10/01/2000-09/30/2001 SBCCOM, DOD $499,999 Combinative Toxicity of Biotoxin Mixtures Role: PI 8. DAAD13-01-C-0053 10/01/01 – 03/31/03 SBCCOM, DOD $434,564/year Combinative Toxicity of Biotoxin Mixtures Role: PI 9. RO3 ES11442 09/01/02 – 08/31/03 NIEHS $73,000/year; $146,000/whole project Modulation of Oxidated Damage by Tea Polyphenols Role: PI 10. DAAD13-02-C-0070 10/01/02 – 03/31/04 SBCCOM, DOD $642,560 Combinative Toxicity of Biotoxin Mixtures Role: PI 11. R21 CA94683-03 10/01/01 – 8/31/05 NCI $182,500/first year; $547,500/whole project Validation of Fumonisin and Microcystin Biomarkers Role: PI

Peer Reviewed Journal Articles: Tang, L., Xu, L., Afriyie-Gyawu, E., Liu, W., Wang, P., Tang, Y., Wang, Z., Henry J. Huebner, H. J., Ankrah, N.-A., Ofori-Adjei, D., Williams, J. H., Wang, J.-S., and Phillips, T. D. (2008). Aflatoxin-albumin adducts correlates with decreased serum levels of vitamins A and E in an adult Ghanaian population. Food Additives & Contam, In press Afriyie-Gyawu, E., Wang, Z., Ankrah, N-A., Johnson, N. M., Tang, L., Xu, L., Ofosuhene, M., Kumi, J., Huebner, H. J., Jolly, P. E., Ellis, Taylor, R., Brattin, B., W. O., Ofori-Adjei, D., Williams, J. H., Wang, J-S., and Phillips, T. D. (2008) Clinical intervention trial with NovaSil clay in Ghanaians at high risk for aflatoxicosis: Nutrient utilization and non-nutritional factors. Food Additives & Contam, In press Jiang, Y., Jolly, P. E., Preko, P. O., Wang, J.-S., Ellis, W. O., Williams, J. H. and Phillips, T. D. (2008) Aflatoxin related immune dysfunction in health and in human immunodeficiency virus disease. Clinic. Develop. Immunol. Article ID 790309, doi:10.1155/2008/790309. Tang, L., Tang, M., Xu, L., Luo, H., Huang, T., Yu, J., Zhang, L., Cox, SB., Gao, W.-M and Wang, J.-S. (2008). Modulation of Aflatoxin Biomarkers in Human Blood and Urine by Green Tea Polyphenols Intervention. Carcinogenesis 29(2):411-417. Wang, J.-S., Luo, H., Wang, P. Tang, L., Yu, J., Huang, T., Cox, S. B., Gao, W. (2008). Validation of Green Tea Polyphenol Biomarkers in a Phase II Human Intervention Trial. Food Chem Toxicol. 46:232-240. Shen, C.-L., P. Wang., Guerrier, J., Yeh, J. K. and J.-S. Wang (2008) Protective effect of green tea polyphenols on bone loss in middle-aged female rats. Osteopros Int. 19(7):979-990. Afriyie-Gyawu, E., Ankrah, N.-A., Huebner, H. J., Ofosuhene, M., Kumi, J., Johnson, N. M., Tang, L., Xu, L., Jolly, P.E., Ellis, W. O., Ofori-Adjei, D., Williams, J. H., Wang, J.-S. & Phillips, T. D. (2008). NovaSil clay intervention in Ghanaians at high risk for aflatoxicosis. I. Study design and clinical outcomes. Food Additives & Contam, 25(1):76-87. Phillips, T. D., Afriyie-Gyawu, E., Williams, J., Huebner, H., N-A. Ankrah, N-A., Ofori-Adjei, D., Jolly, P., Johnson, N., Taylor, J., Marroquin-Cardona, A., Xu, L., Tang, L., Wang, J.-S. (2008). Reducing Human Exposure to Aflatoxin through Use of Clay. Food Additives & Contam, 25(2):134-145. Billam, M., Mukhi, S., Tang, L., Gao, W., and Wang, J.-S. (2008) Toxic response indicators of microcystin-LR in F344 rats following a single dose treatment. Toxcon 51(6):1068-1080. Wang, P., Afriyie-Gyawu, E., Tang, Y., Johnson,N. M., Xu, L., Tang, L., Huebner, H. J., Ankrah, N.-A., Ofori-Adjei, D., Ellis, W., Jolly, P. E., Williams, J. H., Wang, J.-S., Phillips, T. D. (2008).NovaSil clay intervention in Ghanaians at high risk for aflatoxicosis: II. Reduction in biomarkers of aflatoxin exposure in blood and urine, Food Additives & Contam, 25 (5):622-634. Cai, Q., Tang, L. and Wang, J.-S. (2007). Validation of fumonisin biomarkers in F344 rats. Toxicol Appl. Pharmacol. 225:28-39. Tang, L., Guan H., Ding, X. and Wang, J.-S. (2007). Modulation of aflatoxin toxicity and biomarkers by lycopene in F-344 rats. Toxicol Appl. Pharmacol. 219:10-17. Sun, G., Wang, S., Hu, X., Su, J., Huang, T., Yu, J., Tang, L., Gao, W. and Wang, J.-S. (2007). Fumonisin B1 contamination of home-grown corn in high-risk areas of esophageal and liver cancers in China. Food Additives & Contam. 24(2):181-185. Dash, B., Afriyie-Gyawu, E, Huebner, H. J., Porter, W., Wang, J.-S, Jolly, P. E.,Phillips, T. D. (2007). Determinants of the variability of aflatoxin-albumin adduct levels in Ghanaians. J Toxicol. Environ. Health Part A 70:58-66. Jolly, P. E., Jiang, Y., Ellis, W. O., Awuah, R. T., Appawu, J., Nnedu, O., Stiles, J. K., Wang, J-S., Adjei, O., Jolly, C. M., Williams, J. H. (2007). Association between aflatoxin exposure and health characteristics, liver function, hepatitis and malaria infections in Ghanaians. J. Nutri & Environ. Med. 16 (3):1-16. Luo, H., Cox, SB., Gao, W.-M., Yu, J., Tang, L. and Wang, J.-S. (2006). Metabolic Profiling in Validation of Plasma Biomarkers for Green Tea Polyphenols. Metabolomics, 2(4):235-241. Wang, Z., Tang, L., Sun, G., Tang, Y., Xie, Y., Wang, S., Hu, X., Gao, W., Cox, S. B. and Wang J.-S. (2006). Etiological study of esophageal squamous cell carcinoma in an endemic region: a population-based case control study in Huaian, China. BMC Cancer 2006, 6:287 doi:10.1186/1471-2407-6-287 Pan XP, Zhang BH, Tian K, Jones LE, Liu J, Anderson TA, Wang J.-S.,Cobb GP (2006). Liquid chromatography-electrospray ionization-tandem mass spectrometry analysis of octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX). Rapid Commun. Mass Spectrom 20:2222-2226. Egner, PA, Groopman, JD., Wang, J.-S., Kensler, TW., and Friesen, MD (2006). Quantification of aflatoxin B1-N7-guanine in human urine by HPLC-Isotope-Dilution Tandem Mass Spectrometry. Chem. Res. Toxicol. 18:1191-1195. Wang, S-L., He, X-Y., Shen, J., Wang, J.-S. and Hong, J-Y. (2006) The Missense Genetic Polymorphisms of Human CYP2A13: Functional Significance in Carcinogen Activation and Identification of A Null Allelic Variant . Toxicol. Sci. 94(1):38-45. Luo, H., Tang, L., Billam, M., Tang, M.,Huang, T., Yu, J., Wei, Z., Liang, Y., Wang, K., Zhang, Z., Zhang, L., and Wang, J.-S. (2006). Phase IIa chemoprevention trial of green tea polyphenols in high-risk population of liver cancer: II. Modulation of urinary excretion of green tea polyphenols and 8-hydroxydeoxyguanosine. Carcinogenesis. 27:262-268. Billam, M., Tang, L., Cai, Q., Mukhi, S., Guan, H., Wang, P., Wang, Z. and Wang, J.-S. (2006). Seasonal Variations in the Concentration of Microcystin-LR Contamination in Lakes of West Texas. Environ. Toxicol. Chem. 25(2):356-366. McKean, C., Tang, L., Billam, M., Tang, M., Theodorakis, C. W., Kendall, R. J. and Wang, J.-S (2006). Comparative acute and combinative toxicity of aflatoxin B1 and T-2 toxin in animals and immortilized human cell lines. J. Appl Toxicol.26(2):139-147. McKean, C., Tang, L., Tang, M., Billam, M., Wang, Z.,Theodorakis, C. W., Kendall, R. J. and Wang, J.-S (2006). Comparative acute and combinative toxicity of aflatoxin B1 and fumonisin B1 in animals and human cell lines. Food Chem. Toxicol.44(6):868-876. Liu, F., Wang, J.-S., and Theodorakis, C.W. (2006). Genotoxicity and oxidative stress caused by sodium arsenate and sodium perchlorate in zebrafish Danio rerio. Environ Sci. Technol. 40:3429-3436. Dash, B., Afriyie-Gyawu, E, Huebner, H. J., Porter, W., Wang, J.-S, Jolly, P. E.,Phillips, T. D. (2006). Noninvasive identification of inter-individual variation in xenobiotic metabolizing enzymes: implications for cancer epidemiology and biomarker studies. J Toxicol. Environ. Health A 69(13):1203-1216. He, X-Y., Tang, L., Wang, S-L., Cai, Q., Wang, J.-S. and Hong, J-Y. (2006). Efficient activation of aflatoxin B1 by cytochrome P450 2A13, an enzyme predominantly expressed in human respiratory tract. Int. J. Cancer, 118(11):2665-2671. Jolly, P., Jiang, Y., Ellis, W., Awuah, R., Nnedu, O., Phillips, T., Wang, J.-S., Tang, L., Afriyie-Gyawu, E., Person, S., Williams, T. and Jolly, C. (2006). Determinants of aflatoxin levels in Ghanaians: sociodemographic factors, knowledge of aflatoxin and food handling and consumption practices. Int. J. Hyg. Environ.-Health209:345-358. Xu, H.,Sun, G., Wang, S., Hu, X., andWang, J.-S (2006)Determination of aflatoxins and fumonisins in the corn and peanut on sale. J Environ Occup Med.23(3):217-219. 22 (5): 548-550. Sun, G.-J, Wang, S.-K., and Wang, J.-S. (2006). The combined toxicity of two kinds of mycotoxin in Sprague-Dawley rats. Chin J Prev Med 40(5):319-323. Tang, L., Jin, T., Zheng, X. and Wang, J.-S. (2005). Lycopene inhibits the growth of human androgen-independent prostate cancer cells in vitro and in BALB/c nude mice. J. Nutr. 135(2): 287-290. Afriyie-Gyawu, E., Mackie, J., Dash, B., Wiles, M., Taylor, J., Huebner, H., Tang, L., Guan, H., Wang, J.-S. and Phillips, T. D. (2005). Long-term toxicological evaluation of NovaSil clay in the diet of Sprague-Dawley rats. Food Add & Contam. 22 (3): 259-269 Wang, J.-S., Luo, H., Billam, M., Wang, Z., Guan, H., Tang, L., Goldston, T., Afriyie-Gyawu, E., Lovett, C., Griswold, J., Brattin, B., Huebner, H. J. and Phillips, T. D. (2005). Short-term safety evaluation of NovaSil in humans. Food Add. & Contam. 22 (3): 270-279. Jiang, Y., Jolly, P. E., Ellis, W. O., Wang, J.-S., Phillips, T., Williams, J. H. (2005). Aflatoxin B1 albumin adduct levels and cellular immune status in Ghanaians. International Immunol. 17(6):807-814. Xie, Y., Sun, G., Xiong, C., Wang, S., Wang, H. and Wang, J.-S. (2005). Determination of T-2 toxin in staple food from KBD families in Xinhai County, Qinghai Province. Chinese J. Fd Hyg., 17:157-159. Wang, J.-S and Tang, L. (2004). Aflatoxin exposure and human liver cancer. J. of Toxicol, 23:249-271. Tang, L., Tang, M., He, X., Busby, W. F., and Wang, J.-S. (2004). Tumorigenicity of airborne complex mixtures. J. Toxicol. Pharmacol. 18:134-140. Sun, G., Xiong, C., Zhang, Y., Wang, S., Xie, Y. Wang, H., Shi, N. and Wang, J.-S. (2004). Comparison of contents of trace elements in wheat samples from the control and endemic Kashin-Beck disease areas. Trace Element & Health, 21:23-26. Huang, T., Yu, J., Tang, L., Luo, H., Billam, M., Wei, Z., Liang, Y., Li, Y., Wang, K., Shi, J., Cui, Y., Zhang, Z-Q., Zhang, L., Sun, S., Martin, C. and Wang, J.-S. (2004). Phase IIa chemoprevention trial of green tea polyphenols in high-risk population of liver cancer: I. Design, clinical outcome, and baseline biomarker data. J. Int. Cancer Prev. 1:269-280. Wu, Y., Lu, P., Wang, J.-S., Wang, J., Wan, S., Kensler T. W., Groopman, J. D. and Qian, G.-S (2003). Correlation between the genetic polymorphism of EPHX and susceptibility to hepatocellular carcinoma, Tumor, 23:287-289. Sun, G.-J., Qian, G.-S., Jin, X.-P., Chen, J.-G., He, X., Wang S.-K., Jiang, Z-K., and Wang, J.-S. (2002). Assessment of aflatoxin exposure in residents with high incidence of liver cancer. J. Southeast University (Med.Sci.) 21:118-122. Wang, J.-S., Abubaker, S., He, X., Sun, G., Strickland, PT., and Groopman, JD. (2001). Development of aflatoxin B1-lysine adduct monoclonal antibody for human exposure studies. Appl. Environ. Microbiol. 67:2712-2717. Wang, J.-S., Huang, T., Su, JJ., Liang, F., Wei, Z., Liang, Y., Luo, H., Kuang, S-Y., Qian, G-S., Sun, G., He, X., Kensler, TW., and Groopman, JD. (2001). Hepatocellular carcinoma and aflatoxin exposure in Zhuqing Village, Fusui County, People's Republic of China. Cancer Epidemiol. Biomarker & Prev. 10:143-146. 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Advances in research on trichothecenes T-2, DON and NIV. Adv. Physiol. Sci.19:103-109. Wang, J.-S. and Sun, Q. (1988). Mutagenicity studies in vivo of zearalenone, a Fusarium mycotoxin, in mice, Acta Mycologica Sinica 7 (1):59-64. Wang, J.-S., Zhang, Z. Y. and Zhu, X. Y. (1987). Toxicological studies (acute and accumulative toxicity, mutagenicity and cytogenetic evaluation) of Extract from Fucorose, Chinese J. Rail. Med. 15(1):52-56. Tan, W. B., Wang, J.-S., Shan, X. N., Zhang, Z. Y. and Zhu, X. Y. (1986). Evaluation of nutritional status of preschool children from railway workers, Chinese J. Rail. Med. 14 (4):233-236 Wang, J.-S. and Xu, D. D. (1986). Mutagenic and teratogenic studies of mycotoxins extracted from scabby wheat, Acta Mycologica Sinica 5(1):52-62. Wang, J.-S. and Zhu X. Y. (1985). Investigation of aflatoxin M1 contamination in milk and milk powder, Chinese J. Rail. Med. 13 (6):354-357. Wang, J.-S. and Jiang, Z. K. (1984). Assessment of inorganic and organic arsenic accumulation in various seafood, Chinese J. Rail. Med. 12 (5):289-292. Tang, W. L., Jiang, Z. K., Huang, W. Q., Zhang, Z. Y., Zhu, X. Y., and Wang, J.-S. (1983). Toxicological studies of NE-109, a growth regulator of plant, in rats and mice, Chinese J. Prevent. Med. 25 (6):2020-2025. Wang, J.-S. and Xu, D. D. (1982). Absorption, tissue distribution and metabolism of Fusarium mycotoxins, Foreign Med:Public Health, 6:333-341. Wang, J.-S. and Xu, D. D. (1982) Carcinogenicity, mutagenicity and teratogenicity studies of Fusarium mycotoxins from scabby wheat, Foreign Med:Public Health, 2:75-80 Published Reviews and Book Chapters: Groopman, J. D. and Wang, J.-S (2008). Molecular Biomarkers in Comprehensive Toxicology, CRC Press, In press. Wang, J.-S. and Groopman, J. D. (2008). Unit II: Biomarkers: Practical Aspects. Chapter 4. Physical/Chemical/Immunologic Analytical Methods. 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In Walace, KB and Puga, A (eds). Molecular Biology in Toxicology, Taylor & Francis, Washington, DC, pp145-166. Wang, J.-S. and Groopman, J. D. (1998).Toxic liver disorders. In Rom, WR ed. Environmental and Occupational Medicine, 3rd Edition, Lippincot-Raven Publishers, Philadelphia, pp831-841. Groopman, J. D., Scholl, P., and Wang, J.-S. (1996). Epidemiology of human aflatoxin exposure and their relationship to liver cancer. In Walker, C et al (eds) Genetics and Cancer Susceptibility: implications for risk assessment, Wiley-Liss, New York, pp.211-222. Groopman, J. D., Wang, J.-S., and Scholl, P. (1996). Molecular biomarkers for aflatoxins: From adducts to gene mutations to human liver cancer. Canad. J. Physiol. Pharmacol. 74:203-209. Groopman, J. D., Wang, J.-S., Scholl, P., and Kensler, T. W. (1995) Induction of aflatoxin carcinogenesis and mutational spectra. Proc. AACR 36:657-658 Xu, D. D. and Wang, J.-S. (1987). 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