教育背景
1998.09-2001.06,四川农业大学,动物遗传育种与繁殖,农学博士1988.09 - 1991.06, 四川农业大学,动物遗传育种,农学硕士1984.09 - 1988.06, 华中农业大学,畜牧学,农学学士
工作经历
国内工作经历2001.09---现在:华中农业大学,教授、博士生导师,从事教学和科研工作1991.06-2001.08:武汉市畜牧兽医科学研究所,副研究员、研究员,从事科学研究工作国外工作经历2013.7-2015.06(二年):英国皇家兽医学院(Royal Veterinary College),执行居里夫人基金项目 (张淑君为项目主持人)2007.8-2008.06(一年):英国剑桥大学(University of Cambridge),执行英国BBSRC人才基金(张淑君为项目主持人)2005.4-2005.10(半年):英国桑格尔研究所(Sanger Institute),访问和合作研究2004.4-2005.03(一年):在英国剑桥大学(University of Cambridge),访问和合作研究
项目课题经历
论文、成果、著作等
1) Faheem Ahmed Khan, Hui Liu, Hao Zhou, Kai Wang, Muhammad Tahir Ul Qamar, Nuruliarizki Shinta Pandupuspitasari1, Zhang Shujun* Anaysis of Bos taurus and Sus scrofa X and Y chromosome transcriptome highlights reproductive driver genes[J]. Oncotarget, 2017.(SCI, IF= 6.359)2) Nuruliarizki Shinta Pandupuspitasari, Faheem Ahmed Khan, Chunjie Huang, Xing Chen, Shujun Zhang*, Novel attributions of TREMs in immunity, Current Issues in Molecular Biology, 2016, Volume 20 pp 47-54 (SCI, IF=5.75)3) Yuwei Ren, Faheem Ahmed Khan, Nuruliarizki Shinta Pandupuspitasari, Shuaifeng Li, Xingjie Hao, Xing Chen, Jiajun Xiong, Liguo Yang, Mingxia Fan, Shujun Zhang*. Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus modulates interferon (IFN)-β expression mainly through attenuating IRF3 phosphorylation. DNA and Cell Biology. 2016 accepted. (SCI, IF=2.055)4) Yuwei Ren, Faheem Ahmed Khan, Nuruliarizki Shinta Pandupuspitasari, Shujun Zhang*.Immune Evasion Strategies of Pathogens in Macrophages: the Potential for Limiting Pathogen Transmission. Current issues in molecular biology 04/2016; 21:21-40. (SCI, IF=5.75)5) Faheem Ahmed Khan., Pandupuspitasari, NS., ChunJie, HAo, Z., Jamal, M., Zohaib, A., Khan, FA., Hakim, MR. and Zhang, S*.CRISPR/Cas9 Therapeutics: A cure for cancer and other genetic diseases. Accepted 19 May 2016, Oncotarget. (SCI, IF=6.359)6) Chen X, Cheng Z, Werling D, Pollott GE, Salavati M, Johnson KF, Khan FA, Wathes DC,Zhang S*(2016) Bovine P-selectin mediates leukocyte adhesion and is highly polymorphic in dairy breeds. Research in Veterinary Science. 108:85-92.(SCI, IF=1.504)7) Li S, Zhou A, Wang J, Zhang S*. Interplay of autophagy and apoptosis during PRRSV infection of Marc145 cell. Infect Genet Evol. 2016 Jan 13;39:51-54.(SCI, IF: 3.015)8) Wu J, Peng X, Zhou A, Qiao M, Wu H, Xiao H, Liu G, Zheng X, Zhang S, Mei S. MiR-506 inhibits PRRSV replication in MARC-145 cells via CD151. Mol Cell Biochem. 2014 Sep; 394(1-2):275-81(SCI, IF: 2.388)9) Nuruliarizki Shinta Pandupuspitasari, Faheem Ahmed Khan, Chunjie Huang, Xing Chen, Shujun Zhang*, Novel attributions of TREMs in immunity, Current Issues in Molecular Biology, 2016, Volume 20 pp 47-54 (SCI, IF=5.75)10) Zhou A, Li S, Khan FA, Zhang S*. Autophagy postpones apoptotic cell death in PRRSV infection through Bad-Beclin1 interaction. Virulence. 2015 Dec 15:0. (SCI, IF=4.216)11) Xing Chen , Zhangrui Cheng , Shujun Zhang , Dirk Werling , D. Claire Wathes. Combining Genome Wide Association Studies and Differential Gene Expression Data Analyses Identifies Candidate Genes Affecting Mastitis Caused by Two Different Pathogens in the Dairy Cow. Open Journal of Animal Sciences, 2015, 5, 358-39312) Ishwari Kadariya, Jiaxing Wang, Zia ur Rehman, Hamid Ali, Hasan Riaz, JiuYa He, Dinesh Bhattarai, Jia Jia Liu, Shu Jun Zhang*. RNAi-mediated knockdown of inhibin a subunit increased apoptosis in granulose cells and decreased fertility in mice, Journal of Steroid Biochemistry & Molecular Biology, 152 (2015) 161–170 (SCI, IF=4.09). 13) Faheem Ahmed Khan§, Nuruliarizki Shinta, Pandupuspitasari§, Chun-Jie Huang, Xingjie Hao, ShuJun Zhang*, SUMOylation: A link to future therapeutics, Curr. Issues Mol. Biol. 18: 49-56, 2015. (SCI, IF=5.75)14) Li J, Chen Z, Zhao J, Fang L, Fang R, Xiao J, Chen X, Zhou A, Zhang Y, Ren L, Hu X, Zhao Y, Zhang S*, Li N*. Difference in microRNA expression and editing profile of lung tissues from different pig breeds related to immune responses to HP-PRRSV. Sci Rep. 2015 Apr 9; 5:9549. doi: 10.1038/srep09549(SCI, IF=5.078)15) Zhou A, Li S, Zhang S*. miRNAs and genes expression in MARC-145 cell in response to PRRSV infection, Infect Genet Evol. 2014 Oct; 27:173-80. doi: 10.1016/j.meegid.2014.07.023. Epub 2014 Jul 29 (SCI, IF=3.335)16) Zhou A, Li S, Wu J, Khan FA, Zhang S*. Interplay between microRNAs and host pathogen recognition receptors (PRRs) signaling pathways in response to viral infection. Virus Res. 2014 Jan 27. pii: S0168-1702(14)00033-1. doi: 10.1016/j.virusres.2014.01.019(SCI, IF=2.75)17) YB.Jiang, F.A.Khan, N.S.Pandupuspitasari, I.Kadariya, Zh.R.Cheng, Y.W.Ren, X.Chen, A.Zhou, L.G.Yang, D.X.Kong, Sh.J.Zhang*. Analysis of the Binding Sites of Porcine Sialoadhesin Receptor with PRRSV. International Journal of Molecular Sciences, 2013,12: 23955-23979(SCI, IF=2.46)18) Wu JJ, Song LJ, Wu FJ, Liang XW, Yang BZ, Wathes DC, Pollott GE, Cheng Z, Shi de S, Liu QY, Yang LG, Zhang SJ*. Investigation of transferability of BovineSNP50 BeadChip from cattle to water buffalo for genome wide association study. Mol Biol Rep, 2013, 40(2):743-750(SCI, IF= 2.506)19) Y. W. Ren, Y. Y. Zhang, N. A. Affara, C. A. Sargent, L. G. Yang, J. L. Zhao, L. R. Fang, J. Wu, R. Fang, Q. Tong, J. Xiao, J. L. Li, Y. B. Jiang, H. C. Chen, S. J. Zhang*. The polymorphism analysis of CD169 and CD163 related with the risk of porcine reproductive and respiratory syndrome virus (PRRSV) infection. Mol Biol Rep. 2012, 39(11): 9903-9909. DOI 10.1007/s11033-012-1857-8 (SCI, IF=2.929)20) Yu, Y., Wang, J., Burke, S., Khaled W.T., Li, P., Chen, X., Yang, W., Jenkins, J.A., Copeland, N.G., Zhang, S*, and Liu, P*. (2012). Bcl11a is essential for lymphoid development and negatively regulates p53. J Exp Med. 209, 2467-83 (SCI, IF=13.85)21) Wu JJ, Li WM, Feng YP, Zhao RX, Wang C, Yu Y, Yang LG, Zhang SJ*. Sex ratio analysis in dead embryos of chicken during the whole period of incubation period. Journal of Applied Poultry Research. 2012, 21(3):508-512.(SCI, IF=0.846)22) Ao Zhou, Shu-jun Zhang*. Regulation of cell signaling and porcine reproductive and respiratory syndrome virus. Cellular Signaling, 24(5):973-80 2012. Doi:10.1016/ j.cellsig. 2012.01.004. (SCI, IF= 4.09)23) J.J. Wu, J.S. Brickell, L.G. Yang, Z. Cheng, H.Q. Zhao, D.C. Wathes, S.J.Zhang*.Reproductive performance and survival of Chinese Holstein dairy cows in central China, Animal Production Science, 2012, 52(1):11-19. 2012. doi:10.1071/AN11146. (SCI, IF= 1.342)24) S.J. Wang, W.J. Liu, C.A. Sargent, S.H. Zhao, H.B. Liu, X.D. Liu, C. Wang, G. H. Hua, L.G. Yang, N.A. Affara and S. J. Zhang*. Effects of the Polymorphisms of Mx1, BAT2 and CXCL12 Genes on Immunological Traits in Pigs. Molecular Biology Reports, 2012. 39(3):2417-27. 2011, DOI10:1007/s11033-011-0992-y. (SCI, IF=1.857)25) S.J. Wang, W.J. Liu, L.G. Yang, C.A. Sargent, H.B. Liu, C. Wang, X.D. Liu, S.H. Zhao, N.A. Affara, A.X. Liang and S. J. Zhang*. Effects of FUT1 Gene mutation on resistance to infectious disease. Molecular Biology Reports, 2012. 39(3):2805-10. 2011,DOI10:1007/s11033-011-1039-0. (SCI, IF=1.857)26) Wei Wang, Jian Yang, Hui Liu, Dong Lu, Xiongfeng Chen, Zenon Zenonos, Lia Campos, Roland Rad, Ge Guo, Shujun Zhang, Allan Bradley and Pentao Liu. Rapid and Efficient Reprogramming of Somatic Cells to iPSCs by Rarg and Lrh-1. PNAS(Proceedings of the National Academy of Sciences of the United States of America), 108(45):18283-8. October 11, 2011. doi: 10.1073/pnas.1100893108, . (SCI, IF= 9.771)27) Liu HB, Zhang RR, Ko SY, Oyajobi BQ, Papasian CJ, Deng HW, Zhang SJ, Zhao M*. Microtubule assembly affects bone mass by regulating both osteoblast and osteoclast functions, -- Stathmin deficiency produces an osteopenic phenotype in mice. J Bone Miner Res. 26(9):2052-67. 2011 May 6.doi:10.1002/jbmr.419; PMID: 21557310. (SCI, IF=7.056)28) Hui Liu, Wei Wang, Dong Lu, Su-Kit Chew, Song-Choon Lee, Juan Li, George S. Vassiliou, Tony Green, Allan Bradley, Shujun Zhang* and Pentao Liu. Stella-Cre Mice are Highly Efficient Cre Deleters. Genesis, 2011: 49(8):689-95. Genesis.doi: 10.1002/dvg.20741. (SCI, IF=2.266)
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