2002.09 - 2006.06， 华中农业大学，动物科学专业毕业，农业学士2006.09 - 2009.06， 华中农业大学，动物遗传育种与繁殖专业毕业，农学硕士2009.09 - 2013.03， 中科院上海生命科学研究院生物化学与细胞生物学研究所，生物化学与分子生物学专业毕业，理学博士

2013.04-2014.11， 中科院生物化学与细胞生物学研究所、助理研究员2014.12-至今， 华中农业大学、副教授，硕士研究生导师

1.Xie S, Feng Y, Shen Y, Qin H, Zhu M, Zhao S. Cloning of Porcine miRNA let-7b and let-7c by Two Methods. Journal of Agricultural Biotechnology. 2008, 16 (1): 24-31. Article.Chinese. 2.Xie S, Li X, Su L, Gu T, Zhao S. A Facile, Rapid and Effective Method for RNA Quality Determination. Journal of Agricultural Biotechnology. 2009, 17 (2):282-287. Article.Chinese. 3. Xie S, Huang T, Shen Y, Li X, Zhang X, Zhu M, Qin H, Zhao S. Identification and characterization of microRNAs from porcine skeletal muscle.Anim Genet. 2010,41(2):179-90. doi: 10.1111/j.1365-2052.2009.01991.x. 4. Xie S#, Li X#, Liu T, Cao J, Zhong Q, Zhao S. Discovery of porcine microRNAs in multiple tissues by a Solexa deep sequencing approach. PLoS One. 2011, 6(1):e16235. doi: 10.1371/journal.pone.0016235. (#co-first author) 5. Ma W, Xie S, Ni M, Huang X, Hu S, Liu Q, Liu A, Zhang J, Zhang Y. MicroRNA-29a inhibited epididymal epithelial cell proliferation by targeting nuclear autoantigenic sperm protein (NASP). J Biol Chem. 2012, 287(13):10189-99.  doi: 10.1074/jbc.M111.303636. 6．Sun N, Liu D, Chen H, Liu X, Meng F, Zhang X, Chen H, Xie S, Li X, Wu Z. Localization, expression change in PRRSV infection and association analysis of the porcine TAP1 gene. Int J Biol Sci. 2012, 8(1):49-58.doi:10.7150/ijbs.8.49. 7. Zhang J, Xie S, Ma W, Teng Y, Tian Y, Huang X, Zhang Y. A newly identified microRNA,mmu-miR-7578,functions as a negative regulator on inflammatory cytokines tumor necrosis factor-α and interleukin-6 via targeting Egr1 in vivo. J Biol Chem.2013, 288(6):4310-20.doi: 10.1074/jbc.M112.351197. 8. Xie S#, Xu J#, Ma W, Liu Q, Han J, Yao G, Huang X, Zhang Y. Lcn5 promoter directs the region-specific expression of cre recombinase in caput epididymidis of transgenic mice. Biol Reprod. 2013, 88(3):71.doi: 10.1095/biolreprod.112.104034. (#co-first author) 9. Ma W, Hu S, Yao G, Xie S, Ni M, Liu Q, Gao X, Zhang J, Huang X, Zhang Y. An androgen receptor-microrna-29a regulatory circuitry in mouse epididymis. J Biol Chem. 2013, 288(41):29369-81.doi: 10.1074/jbc.M113.454066. 10. Xie S, Shen B, Zhang C, Huang X, Zhang Y. sgRNAcas9: a software package for designing CRISPR sgRNA and evaluating potential off-target cleavage sites. PLoS One. 2014,9(6):e100448.doi: 10.1371/journal.pone.0100448. 11. Chu C, Zheng G, Hu S, Zhang J, Xie S, Ma W, Ni M, Tang C, Zhou L, Zhou Y, Liu M, Li Y, Zhang Y. Epididymal Region-Specific miRNA Expression and DNA Methylation and Their Roles in Controlling Gene Expression in Rats. PLoS One. 2015, 10(4):e0124450. doi: 10.1371/journal.pone.0124450. 12. Zhao C, Zhang Y, Li G, Chen J, Li J, Ren R, Ni P, Zhao S, Xie S*.Development of a graphical user interface for sgRNAcas9 and its application. Yi Chuan. 2015, 37(10):1061-72. doi: 10.16288/j.yczz.15-292. Article.Chinese. 13.Xie S, Zhang Y, Zhang L, Li G, Zhao C, Ni P, Zhao S.sgRNA design for the CRISPR/Cas9 system and evaluation of its off-target effects. Yi Chuan. 2015, 37(11):1125-36. doi: 10.16288/j.yczz.15-093. Review. Chinese. 14.Xie S*, Liu X, Zeng C, Ma Y, Wang H.The application of CRISPR/Cas9 technology in the innovative experimental teaching of molecular biology. Chemisty of life, 2016, 36(1): 117-125. doi: 10.13488/j.smhx.20160119. Article.Chinese. 15.Xu J, Yao G, Ru Y, Xie S*. Expression of tamoxifen-inducible CRE recombinase in Lcn5-CreERT2 transgenic mouse caput epididymis. Mol Reprod Dev. 2017, 84(3):257-264. doi:10.1002/mrd.22772. 16.Chen R, Du J, Ma L, Wang L, Xie S, Yang C, Lan X, Pan C, Dong W. Comparative microRNAome analysis of the testis and ovary of the Chinese giant salamander. Reproduction, 2017,154(3):169-179.doi: 10.1530/REP-17-0109. 17.Cheng Y, Wei Z, Xie S, Peng Y, Yan Y, Qin D, Liu S, Xu Y, Li G, Zhang L. Alleviation of Toxicity Caused by Overactivation of Pparα through Pparα-Inducible miR-181a2. Molecular Therapy-Nucleic Acids, 2017, 9:195-206.DOI:http://dx.doi.org/10.1016/j.omtn.2017.09.008. 18. Zhao C, Zheng X, Qu W, Li G, Li X, Miao Y, Han X, Liu X, Li Z, Ma Y, Shao Q, Li H, Sun F*, Xie S*, Zhao S*. CRISPR-offinder: a CRISPR guide RNA design and  off-target searching tool for user-defined protospacer adjacent motif. Int J Biol Sci, 2017,13(11):1470-1478.d:10.7150/ijbs.21312. (*Co-Corresponding authors)