2004.09 - 2009.06， 华中农业大学，动物医学专业毕业，农学学士2009.09 - 2014.06， 华中农业大学，预防兽医学专业毕业，农学博士

2012.02-2012.08，上海国家人类基因组南方研究中心合作研究2012.10-2014.04，美国约翰霍普金斯大学医学院联合研究

A著作类B论文类1.Xiangru Wang, Xiaojuan Xu, Shu Zhang, Fengjuan Guo, Xuwang Cai, Huanchun Chen. Identification and analysis of potential virulence-associated genes in Haemophilus parasuis based on genomic subtraction. Microb Pathog, 2011, 51: 291–296. (IF=2.0) 2.Xiangru Wang, Xiaojuan Xu, Yucong Wu, Lanying Li, Ruijuan Cao, Xuwang Cai, Huanchun Chen. Polysaccharide biosynthesis protein CapD is a novel pathogenicity-associated determinant of Haemophilus parasuis involved in serum-resistance ability. Vet Microbiol, 2013, 164: 184-189. (IF=3.327) 3.Xiangru Wang, Haihong Hao, Zhuofei Xu, Huajun Zheng, Canying Liu, Liuya Wei, Ruixuan Zhang, Dingren Bi, Huanchun Chen, Chen Tan. Plasmid-mediated multidrug resistance and virulence in an avian pathogenic Escherichia coli strain isolated in China. J Global Antimicrob Resist, 2014, 2: 57-58. (IF=1.086) 4.Liping Chen, Xuwang Cai, Xiangru Wang, Xueli Zhou, Dongfang Wu, Xiaojuan Xu, Huanchun Chen. Characterization of plasmid-mediated lincosamide resistance in a field isolate of Haemophilus parasuis. J Antimicrob Chemother, 2010, 65: 2256-8. (IF=5.068) 5.陈西, 王湘如, 徐晓娟, 郭凤娟, 陈焕春, 蔡旭旺. 副猪嗜血杆菌细胞致死膨胀毒素的细胞毒性研究, 畜牧兽医学报, 2011, 42 (12): 1750-1755. 6.Canying Liu, Huajun Zheng, Minjun Yang, Zhuofei Xu, Xiangru Wang, Liuya Wei, Biao Tang, Feng Liu, Yanyan Zhang, Yi Ding, Xibiao Tang, Bin Wu, Timothy J. Johnson, Huanchun Chen, Chen Tan. Genome analysis and in vivo virulence of porcine extraintestinal pathogenic Escherichia coli strain PCN033. BMC Genomics, 2015, 16(1): 717. (IF=3.986) 7.Yi Ding, Dongmei Zhu, Jianmin Zhang, Longsheng Yang, Xiangru Wang, Huanchun Chen, Chen Tan. Virulence determinants, antimicrobial susceptibility, and molecular profiles of Erysipelothrix rhusiopathiae strains isolated from China. Emerg Microbes Infec, (2015) 4, e69 (IF=4.012) 8.Jing Chen, Lijie Su, Xiangru Wang, Tao Zhang, Feng Liu, Huanchun Chen, Chen Tan. Polyphosphate Kinase Mediates Antibiotic Tolerance in Extraintestinal Pathogenic Escherichia coli PCN033. Front Microbiol, 2016, 19(7): 724. doi: 10.3389/fmicb.2016.00724. (IF=4.165) 9.Yan Zhang, Dandan Ding, Manli Liu, Xiaopei Yang, Bingbing Zong, Xiangru Wang, Huanchun Chen, Weicheng Bei, Chen Tan. Effect of the glycosyltransferases on the capsular polysaccharide synthesis of Streptococcus suis serotype 2. Microbiol Res. 2016, 185: 45-54. (IF=2.723) 10.Ying Peng, Xiangru Wang, Jin Shou, Bingbing Zong, Yan Zhang, Jia Tan, Jing Chen, Linlin Hu, Yongwei Zhu, Huanchun Chen, Chen Tan. Roles of Hcp family proteins in the pathogenesis of the porcine extraintestinal pathogenic Escherichia coli type VI secretion system. Sci Rep. 2016, 27(6): 26816. (IF=5.228) 11.Jiachen Huang1, Xiangru Wang1, Qi Cao, Fenfen Feng, Xiaojuan Xu, Xuwang Cai. ClpP participates in stress tolerance and negatively regulates biofilm formation in Haemophilus parasuis. Vet Microbiol, 2016, 182: 141-9. (Co-first, IF=2.511) 12Xiangru Wang, Liuya Wei, Bin Wang, Ruixuan Zhang, Canying Liu, Dingren Bi, Huanchun Chen, Chen Tan. Complete genome sequence and characterization of avian pathogenic Escherichia coli field isolate ACN001. Stand. Genomic Sci., 2016, 11:13. (IF=1.594) 13Ruicheng Yang, Wentong Liu, Ling Miao, Xiaopei Yang, Jiyang Fu, Beibei Dou, Aoling Cai, Xin Zong, Chen Tan, Huanchun Chen, Xiangru Wang#. Induction of VEGFA and Snail-1 by meningitic Escherichia coli mediates disruption of the blood-brain barrier. Oncotarget, 2016, 7(39): 63839-63855. doi: 10.18632/oncotarget.11696. (Corresponding author, IF=5.008, 5 year IF=5.415) 14.Xiangru Wang, Ravi Maruvada, Andrew J Morris, Jun O Liu, Michael J. Wolfgang, Dong Jae Baek, Robert Bittman and Kwang Sik Kim. Sphingosine 1-Phosphate Activation of EGFR as a Novel Target for Meningitic Escherichia coli Penetration of the Blood–Brain Barrier. PLoS Pathog, 2016, 12(10): e1005926. doi:10.1371/journal.ppat.1005926 (IF=7.003, 5 year IF=7.758) 15. Xiaopei Yang, Jiyang Fu, Ruicheng Yang, Wentong Liu, Tao Zhang, Bo Yang, Ling Miao, Beibei Dou, Chen Tan, Huanchun Chen, Xiangru Wang#. EGFR transactivation contributes to neuroinflammation in Streptococcus suis meningitis. J Neuroinflamm, 2016, 13: 274. doi: 10.1186/s12974-016-0734-0 (IF=4.667, 5 year IF=5.366) 16.Ruicheng Yang, Fei Huang, Jiyang Fu, Beibei Dou, Bojie Xu, Ling Miao, Wentong Liu, Xiaopei Yang, Chen Tan, Huanchun Chen, Xiangru Wang#. Differential transcription profiles of long non-coding RNAs in primary human brain microvascular endothelial cells in response to meningitic Escherichia coli. Sci Rep. 2016, 6:38903 (IF=5.228, 5 year IF=5.525) 17.Feng Liu, Jiyang Fu, Canying Liu, Jing Chen, Minhua Sun, Huanchun Chen, Chen Tan, Xiangru Wang#. Characterization and distinction of two flagellar systems in extraintestinal pathogenic Escherichia coli PCN033. Microbiol Res. 2017, 196: 69-79. (IF=2.723, 5 year IF=2.695) 18.Pei Li, Rui Wang, Wenqi Dong, Linlin Hu, Bingbing Zong, Yanyan Zhang, Xiangru Wang, Aizhen Guo, Anding Zhang, Yaozu Xiang, Huanchun Chen, Chen Tan. Comparative proteomics analysis of human macrophages infected with virulent Mycobacterium bovis. Front Cell Infect Microbiol. 2017, 7: 65. (IF=5.218) 19.Bingbing Zong, Liuya Wei, Yan Zhang, Xiangru Wang, Huanchun Chen, Chen Tan. Effect of kpsM on the virulence of porcine extraintextinal pathogenic Escherichia coli. FEMS Microbiol Lett. 2016, Oct 12. pii: fnw232. (IF=1.858) 20.Qi Cao, Fenfen Feng, Huan Wang, Xiaojuan Xu, Huanchun Chen, Xuwang Cai, Xiangru Wang#. Haemophilus parasuis CpxRA two-component system confers bacterial tolerance to environmental stresses and macrolide resistance. Microbiol Res. 2018, 206: 177-185. (IF=3.04)