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申邦

领域:现代农业 学校:华中农业大学职称:教授

真核病原的致病机制、人兽共患病、基因编辑、动物疫苗...

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教育背景

2001.09 - 2005.07, 武汉大学,生物科学专业毕业,学士2005.08 - 2010.08, 堪萨斯大学,微生物学专业毕业,博士

工作经历

2010.12-2014.11,华盛顿大学医学院, 博士后。2014.12-现在,华中农业大学教授、博士生导师。

项目课题经历

论文、成果、著作等

A著作类B论文类Xia N, Yang J, Ye S, Zhang L, Zhou Y, Zhao J, David Sibley L, Shen B*. Functional analysis of Toxoplasma lactate dehydrogenases suggests critical roles of lactate fermentation for parasite growth in vivo. Cell Microbiol. 2017 Oct 13. doi: 10.1111/cmi.12794. Pan M, Lyu C, Zhao J, Shen B*. Sixty Years (1957-2017) of Research on Toxoplasmosis in China-An Overview. Front Microbiol. 2017 Sep 25;8:1825. doi: 10.3389/fmicb. Shen B*, Powell RH, Behnke MS*. QTL Mapping and CRISPR/Cas9 Editing to Identify a Drug Resistance Gene in Toxoplasma gondii. J Vis Exp. 2017 Jun 22;(124). doi: 10.3791/55185. Shen B, Yuan Y, Cheng J, Pan M, Xia N, Zhang W, Wang Y, Zhou Y, Zhao J. Activation of chronic toxoplasmosis by transportation stress in a mouse model. Oncotarget, 2016 Dec 27;7(52):87351-87360Shen B, Brown K, Long S, Sibley LD. Development of CRISPR/Cas9 for Efficient Genome Editing in Toxoplasma gondii. Methods Mol Biol. 2017;1498:79-103. Wang JL, Huang SY, Behnke MS, Chen K, Shen B*, Zhu XQ*, The Past, Present, and Future of Genetic Manipulation in Toxoplasma gondii. Trends Parasitol. 2016 Jul;32(7):542-53Zhang W, Li L, Xia N, Zhou Y, Fang R, He L, Hu M, Shen B*, Zhao J*. Analysis of the virulence determination mechanisms in a local Toxoplasma strain (T.gHB1) isolated from central China. Parasitol Res. 2016 Oct;115(10):3807-15Wang Y, Fang R, Yuan Y, Pan M, Hu M, Zhou Y, Shen B, Zhao J*. Identification of host proteins, Spata3 and Dkk2, interacting with Toxoplasma gondii micronemal protein MIC3. Parasitol Res. 2016, 115(7):2825-35Huang Y, He L*, Hu J, Miao XY, He P, He JW, Yu L, Ngabu Malobi, Zhou YQ, Shen B, Zhao JL*. Characterization and annotation of Babesia orientalis apicoplast genome. Parasites & Vectors. 2015 Oct 16;8(1):543. He L, Fan LZ, Liu Q, Hu J, Miao XY, Huang Y, He P, He JW, Yu L, Muhammad K, Zhou YQ, Shen B, Zhao JL*. Identification and characterization of a novel 34 kDa merozoite protein in Babesia orientalis. Vet. Parasitol. 2015 Sep. 15;212(3-4):411-6. Bang Shen & L David Sibley. (2014) Toxoplasma aldolase is required for metabolism but dispensable for host cell invasion. PNAS. 111(9):3567-72. Bang Shen, Kevin Brown, Tobie D Lee & L David Sibley. (2014) Efficient gene disruption in diverse strains of Toxoplasma gondii using CRISPR/CAS9. mBio, 13;5(3):e01114-14Bang Shen, Jeffrey S. Buguliskis, Tobie D. Lee & L. David Sibley. (2014) Functional analysis of rhomboid proteases during Toxoplasma invasion. mBio;5(5):e01795-14Bang Shen & L David Sibley. (2012) The moving junction, a key portal to host cell invasion by apicomplexan parasites. Current Opinion in Microbiology. 15(4):449-55Bang Shen & Joe Lutkenhaus. (2009) The conserved C-terminal tail of FtsZ is required for the septal localization and division inhibitory activity of MinCC/MinD. Molecular Microbiology. 72(2) 410-424. Bang Shen & Joe Lutkenhaus. (2010) Examination of the interaction between FtsZ and MinCN in E. coli suggests how MinC disrupts Z rings. Molecular Microbiology. 75: 1285-1298. Bang Shen & Joe Lutkenhaus. (2011) Differences in MinC/MinD sensitivity between polar and internal Z rings in Escherichia coli. Journal of Bacteriology. 193(2):367-76. Sebastien Pichoff, Bang Shen, Bradley Sullivan, Joe Lutkenhaus. (2012) FtsA mutants impaired for self-interaction bypass ZipA suggesting a model in which FtsA

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