教育背景
1997.09 - 2001.06, 山东农业大学,畜牧专业毕业,农学学士2001.09 - 2004.06, 山东农业大学,动物遗传育种与繁殖专业毕业,农学硕士2005.09 - 2008.06, 中国科学院动物研究所,生理学专业毕业,理学博士2008.08 - 2009.08, 美国密苏里大学哥伦比亚分校,博士后
工作经历
2009.08-2013.03,美国国立卫生研究院环境健康科学研究所(NIH/NIEHS),访问学者(visiting fellow)2013.03-2014.09,美国国立卫生研究院环境健康科学研究所(NIH/NIEHS),研究学者(research fellow)2014.09-今,华中农业大学教授、博士生导师
项目课题经历
论文、成果、著作等
论文类1. Tao C*, Li J*, Zhang X, Chen B, Chi D, Zeng Y, Niu Y, Wang C, Cheng W, Wu W, Pan Z, Lian J, Liu H#, Miao YL#. Dynamic Reorganization of Nucleosome Positioning in Somatic Cells after Transfer into Porcine Enucleated Oocytes. Stem Cell Reports. 2017 Aug 8;9(2):642-653. 2. Wang T, Gao YY, Chen L, Nie ZW, Cheng W, Liu1 X, Schatten H, Zhang X#, Miao YL#. Melatonin prevents postovulatory oocyte aging and promotes subsequent embryonic development in the pig. Aging 2017 Jun 26;9(6):1552-1564. 3. Zhang X, Liu X, Chen L, Wu DY, Nie ZW, Gao YY, Miao YL#. Caffeine delays oocyte aging and maintains the quality of aged oocytes safely in mouse. Oncotarget. 2017 Mar 28;8(13):20602-20611. 4. Gao YY, Chen L, Wang T, Nie ZW, Zhang X, Miao YL#. Oocyte aging-induced Neuronatin (NNAT) hypermethylation affects oocyte quality by impairing glucose transport in porcine. Sci Rep. 2016 Oct 26;6:36008. 5. Miao YL, Stein P, Jefferson WN, Padilla-Banks E, Williams CJ. Calcium influx-mediated signaling is required for complete mouse egg activation. Proc Natl Acad Sci U S A. 2012 Mar 13;109(11):4169-74. 6. Miao YL and Williams CJ. Calcium signaling in mammalian egg activation and embryo development: the influence of subcellular localization. Molecular Reproduction and Development. 2012 Nov;79(11):742-56. 7. Miao YL, Zhang X, Zhao JG, Zhao MT, Spate L, Murphy CN, Prather RS, Sun QY, Schatten H. Effects of griseofulvin on in vitro porcine oocyte maturation and embryo development. Environmental and Molecular Mutagenesis. 2012 Aug;53(7):561-6. 8. Chang G*, Miao YL*, Zhang Y, Liu S, Kou Z, Ding J, Chen DY, Sun QY, Gao S. Linking incomplete reprogramming to the improved pluripotency of murine embryonal carcinoma cell-derived pluripotent stem cells. PLoS One. 2010 Apr 26;5(4):e10320. 9. Miao YL, Kikuchi K, Sun QY, Schatten H. Oocyte aging: cellular and molecular changes, developmental potential, and reversal possibility. Human Reproduction Update. 2009 Sep-Oct;15(5):573-85. 10. Miao YL, Sun QY, Zhang X, Zhao JG, Zhao MT, Spate L, Prather RS, Schatten H. Centrosome abnormalities in porcine oocytes during aging. Environmental and Molecular Mutagenesis. 2009 Oct;50(8):666-71. 11. Miao YL, Shi LH, Lei Zl, Huang JC, Yang JW, Ouyang YC, Sun QY, Chen DY. Effects of caffeine on in vivo and in vitro oocyte maturation in mice. Theriogenology. 2007 Sep 1; 68(4):640-5. 12. Miao YL, Liu XY, Qiao TW, Miao DQ, Luo MJ, Tan JH. Cumulus cells accelerate aging of mouse oocytes. Biology of Reproduction. 2005 Nov; 73(5):1025-31. 13. Miao YL, Ma SF, Liu XY, Miao DQ, Chang ZL, Luo MJ, and Tan JH. Fate of the first polar bodies in mouse oocytes. Molecular Reproduction and Development. 2004 Sep; 69(1):66-76. 14. Qiao J*, Wang ZB*, Feng HL*, Miao YL, Wang Q, Yu Y, Wei YC, Yan J, Wang WH, Shen W, Sun SC, Schatten H, Sun QY. The Root of Reduced Fertility in Aged Women and Possible Therapentic Options: Current Status and Future Perspects. Mol Aspects Med. 2014 Aug;38:54-85. 15. Wang L, Miao YL*, Zheng X*, Lackford B*, Han L, Yao C, Ward J, Burkholder A, Lipchina I, Fargo D, Hochedlinger K, Shi Y, Williams C, Hu G. The THO Complex Regulates Pluripotency Gene mRNA Export and Controls Embryonic Stem Cell Self-Renewal and Somatic Cell Reprogramming. Cell Stem Cell. 2013 Dec 5;13(6):676-90.
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