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领域:现代农业 学校:华中农业大学职称:副教授

巴贝斯虫基因组学、入侵机制、疫苗的开发、早期诊断抗原和药物靶标的筛选...

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教育背景

2006/09 – 2011/06 华中农业大学预防兽医学,博士2009/09 – 2009/12 南非比勒陀利亚大学兽医学院,合作课题交流2008/10 – 2009/01 南非比勒陀利亚大学兽医学院,合作课题交流2002/09 – 2006/07 华中农业大学动物医学院,学士

工作经历

2016/1 – 至今 华中农业大学动物医学院,副教授2014/1 – 2015/12 华中农业大学动物医学院,副研究员2011/08 – 2013/12 华中农业大学动物科技学院2011/09 – 2013/3 美国德州理工大学健康科学中心

项目课题经历

论文、成果、著作等

B论文类He L., Miao XY., Hu JF., Huang Y., He P., He JW., Yu L., Malobi N., Shi LG., Zhao JL. First molecular detection of Babesia gibsoni in dogs from Wuhan, China. Frontiers in Microbiogy. doi.org/10.3389/fmicb.2017.01577. He L., Liu Q., Yao BA., Zhou YQ., Hu M., Fang R., Zhao JL. A historical overview of research on Babesia orientalis, a protozoan parasite infecting water buffalo. Frontiers in Microbiogy. doi.org/10.3389/fmicb.2017.01323. Ngabu Malobi, He L*, Yu L, He P, He J, Sun Y, Huang Y, Zhao J*. Molecular cloning and characterization of Babesia orientalis Rhoptry Neck 2 BoRON2 protein. J. Parasitol. Res. 2017; 2017:7259630. doi: 10.1155/2017/7259630. Epub 2017 Jul 9. Huang Y, He L*, Hu J, Miao XY, He P, He JW, Yu L, NgabuMalobi, Zhou YQ, Shen B, Zhao JL*. Characterization and annotation of Babesia orientalis apicoplast genome. Parasites & Vectors. 2015 Oct 16;8(1):543. He L, Fan LZ, Liu Q, Hu J, Miao XY, Huang Y, He P, He JW, Yu L, Muhammad K,Zhou YQ, Shen B, Zhao JL.Identification and characterization of a novel 34 kDamerozoite protein in Babesia orientalis. Vet. Parasitol. 2015, Sep 15;212(3-4):411-6. doi:10.1016/j.vetpar.2015.06.031 He L, Fan LZ, Hu JW, Miao XY, Huang Y, Zhou YQ, Hu M, Zhao JL.Characterisation of a Babesiaorientalis apical membrane antigen, and comparison of its orthologues among selected apicomplexans. Ticks Tick Borne Dis. 2015 6:290-296 Yu Q, He L*, Zhang WJ, Cheng JX, Hu JF, Miao XY, Huang Y, Fang LZ, Muhammad Kasib Khan, Zhou YQ, Hu M, Zhao JL*. Molecular cloning and characterization of Babesia orientalis rhoptry-associated protein 1. Vet. Parasitol. 2014, 205:499-505. He L, YuQ, ZhangWJ, ZhangQL, FanLZ, MiaoXY, Muhammad KK, HuM, ZhouYQ, Zhao JL*. Molecular cloning and characterization of a novel heat shock protein 20 of Babesiaorientalis. Vet. Parasitol. 2014, 204:177-183. He L, Zhang Y, Zhang QL, Zhang WJ, Feng HH, Muhammad KK, Hu M, Zhou YQ, Zhao JL*. Mitochondrial genome of Babesiaorientalis, apicomplexan parasite of water buffalo (Bubalusbabalus, Linnaeus, 1758) endemic in China. Parasites & Vectors 2014. 7:82. doi:10.1186/1756-3305-7-82. Khan MK, He L, Zhang W, Wang Y, Tao Q, Song Q, Sajid MS, Yu Q, Hu J, Fang R, Hu M, Zhou Y, Zhao J. Identification of two novel HSP90 proteins in Babesia orientalis: molecular characterization, and computational analyses of their structure, function, antigenicity and inhibitor interaction. Parasites & Vectors 2014. 7:293. doi: 10.1186/1756-3305-7-293. Song WJ, Song QQ, He L, Zhou YQ, Zhao JL. The establishment and application of a semi-nested PCR assay for the detection of Mycoplasma ovis. Small Ruminant Research. 2014, 119 (1-3): 176-181. Song Q, Zhang W, Song W, Liu Z, Khan MK, He L, Fang R, Li P, Zhou Y, Hu M, Zhao J. Seroprevalence and risk factors of Mycoplasma suis infection in pig farms in central China. Prev Vet Med. 2014 Nov 1;117(1):215-21. Muhammad Kasib Khan, Muhammad SohailSajid, Hasan Riaz, Nazia Ehsan Ahmad, He L, et al. The global burden of fasciolosis in domestic animals with an outlook on the contribution of new approaches for diagnosis and control. Parasitol. Res. 2013, 2421 – 2430. Muhammad Kasib Khan, He L, Altaf Hussain, SabitaAzam, Zhang WJ, Wang LX, Zhang QL, Hu M, Zhou YQ, Zhao JL*. Molecular epidemiology of Theileriaannulata and identification of 18S rRNA gene and ITS regions sequences variants in apparently healthy buffaloes and cattle in Pakistan. Infection Genetics Evolution. 2013, 13: 124 – 132. He L, ZhouYQ, Fang R, Feng H, Wang LX, Tu P, Marinda C. Oosthuizen, Zhao JL*. Occurance of Theileria and Babesia species in water buffalo (Bubalusbabalis, Linnaeus, 1758) in the Hubei province, South China. Veterinary Parasitology. 2012, 186: 490 – 496. He L, MuhanmadKasib Khan, ZhangWJ, ZhangQL, ZhouYQ, HuM, ZhaoJL*. Detection and identification Theileria infectious in sika deer (Cervus Nippon) in China.The Journal of Parasitology. 2012, 98: 598 – 603HeL, FengHH, ZhangQL, ZhangWJ, MuhanmadKasib Khan, HuM, ZhouYQ, ZhaoJL*. Development and evaluation of real-time PCR assay for the detection of Babesiaorientalis in water buffalo (Bubalusbubalis, Linnaeus, 1758). The Journal of Parasitology. 2011, 97: 1166 – 1169. WangLX, He L, FangR, SongQQ, TuP, ZhouYQ, ZhaoJL*. Loop-mediated isothermal amplification (LAMP) assay for detection of Theileriasergenti infection targeting the p33 gene. Veterinary Parasitology. 2010, 171:159-162. He L, ZhouYQ, Marinda C. Oosthuizen, ZhaoJL*. Loop-mediated isothermal amplification (LAMP) detection of Babesiaorientalis in water buffalo (Bubalusbabalis, Linnaeus, 1758) in China. Veterinary Parasitology. 2009, 165: 36-40. HeL, Liu Q, Melvyn Quan, Zhou DN, Zhao JL. Molecular cloning and phylogenetic analysis of Babesiaorientalis heat shock protein 70. Veterinary Parasitology. 2009, 162:183-191. Fang R, Nie H, Wang ZS, Tu P, Zhou DN, Wang LX, He L, Zhou YQ, Zhao JL*. Protective immune response in BALB/c mice induced by a suicidal DNA vaccine of the MIC3 gene of Toxoplasma gondii. Veterinary Parasitology. 2009, 164:134-140. Wang LX, Zhao LH, He L, Liu Q, Zhou DN, Zhou YQ, Zhao JL*. An indirect ELISA for detection of Theileriasergenti antibodies in water buffalo using a recombinant major piroplasm surface protein, Veterinary Parasitology. 2008, 170:323-326.

专利、著作版权等

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