教育背景
1984.10—1989.01 德国慕尼黑大学 攻读博士研究生
工作经历
1989.02—1993.09 华中农业大学 讲师、副教授1993.10—1994.10 德国慕尼黑大学 合作科研1994.11—2002.12 华中农业大学 教授、博士生导师、畜牧兽医学院院长2003.01—2007.12 华中农业大学 教授、副校长、中国工程院院士2008.01—至 今 华中农业大学 教授、中国工程院院士
项目课题经历
论文、成果、著作等
A著作类1.《规模化猪场疫病控制及净化》主编2.《兽医手册》主编3.《伪狂犬病》主编B论文类 (部分)1.Ding Z, An K, Xie LL, Wu W, Zhang RX, Wang D, Fang Y, Chen HC, Xiao SB, Fang LR*. Transmissible gastroenteritis virus infection induces NF-kappa B activation through RLR-mediated signaling. Virology. 2017, 507: 170-178 3.3542.He W, Zhao ZK, Anees A, Li YC, Ashraf U, Chen Z, Song YF, Chen HC, Cao SB, Ye J*. p21-Activated Kinase 4 Signaling Promotes Japanese Encephalitis Virus-Mediated Inflammationin Astrocytes. Frontiers In Cellular And Infection Microbiology. 2017, 7 4.33.Zheng Chengkun, Zhao Xigong, Zeng Ting, Cao Manman, Xu Jiali, Shi Guolin, Li Jinquan, Chen Huanchun, Bei Weicheng*. Identification of four type II toxin-antitoxin systems in Actinobacillus pleuropneumoniae. FEMS microbiology letters.2017, 7 1.76494.Sun X, Wang SY, Lin X , Zhao LZ, Zhang D, Yi CY, Sun XM, Chen HC, Jin ML*.Proteome analysis of Duck Tembusu virus (DTMUV)-infected BHK-21 cells.Proteomics.2017, 17:12 4.0415.Xu Jiali, Zheng Chengkun, Cao Manman, Zeng Ting, Zhao Xigong, Shi Guolin, Chen Huanchun, Bei Weicheng*.The manganese efflux system MntE contributes to the virulence of Streptococcus suis serotype 2.Microbial pathogenesis.2017, 110:23-30 2.0096.Wang X, Wu CX, Song XR, Chen HC, Liu ZF*. Comparison of pseudorabies virus China reference strain with emerging variants reveals independent virus evolution within specific geographic regions.Virology. 2017, (506): 92-98 3.3547.Qian Suhong, Fan Wenchun, Liu Tingting, Wu Mengge, Zhang Huawei, Cui Xiaofang, Zhou Yun, Hu Junjie, Wei Shaozhong, Chen Huanchun, Li Xiangmin*, Qian Ping. Seneca Valley Virus suppresses host type I interferon production by targeting adaptor proteins MAVS TRIF and TANK for cleavage. Journal of virology.2017, 4 Journal of virology 3.3548.Wang SY, Sun X, Yi CY, Zhang D, Lin X, Sun XM, Chen HC, Jin ML*. AGO2 Negatively Regulates Type I Interferon Signaling Pathway by Competition Binding IRF3 with CBP/p300.Frontiers In Cellular And Infection Microbiology.2017, 7 4.39.Rasheed MA, Qi JJ, Zhu XF, He CF, Menghwar H, Khan FA, Gang Z, Zubair M, Hu CM, Chen YY, Chen HC, Guo AZ*. Comparative Genomics of Mycoplasma bovis Strains Reveals That Decreased Virulence with Increasing Passages Might Correlate with Potential Virulence-Related Factors. Frontiers In Cellular And Infection Microbiology. 2017, 7 4.3 10.Wang Y, Li JT, Zhang AD, Zhu WF, Zhang Q, Xu ZM, Yan SX, Sun XM, Chen HC, Jin ML*. iTRAQ-based quantitative proteomic analysis reveals potential virulence factors of Erysipelothrix rhusiopathiae. Journal Of Proteomics.2017, 160: 28-37 3.91411.Zou Z, Huang K, Wei YM, Chen HC, Liu ZD, Jin ML*. Construction of a highly efficient CRISPR/Cas9-mediated duck enteritis virus-based vaccine against H5N1 avian influenza virus and duck Tembusu virus infection. Scientific Reports.2017, 7 4.25912.Peng Z, Liang W, Liu WJ, Chen HC, Wu B*.Genome characterization of Pasteurella multocida subspecies septica and comparison with Pasteurella multocida subspecies multocida and gallicida. Archives Of Microbiology.2017, 199(4): 635-640 1.613.Ye Jing, Chen Zheng, Li Yunchuan, Zhao Zikai, He Wen, Zohaib Ali, Song Yunfeng, Deng Chenglin, Zhang Bo, Chen Huanchun, Cao Shengbo*.Japanese Encephalitis Virus NS5 Inhibits Type I Interferon (IFN) Production by Blocking the Nuclear Translocation of IFN Regulatory Factor 3 and NF-kappaB. Journal of virology.2017, 91:8 3.35414.Zhou YR, Fang LR, Wang D, Cai KM, Chen HC, Xiao SB*. Porcine Reproductive and Respiratory Syndrome Virus Infection Induces Stress Granule Formation Depending on Protein Kinase R-like Endoplasmic Reticulum Kinase (PERK) in MARC-145 Cells. Frontiers In Cellular And Infection Microbiology.2017, 7 4.315.Zhang Shishuo, Wang Ruifang, Su Huijuan, Wang Biaoxiong, Sizhu Suolang, Lei Zhixin, Jin Meilin, Chen Huanchun, Cao Jiyue, Zhou Hongbo*. Sus scrofa miR-204 and miR-4331 Negatively Regulate Swine H1N1/2009 Influenza A Virus Replication by Targeting Viral HA and NS Respectively. International journal of molecular sciences.2017, 18:4 3.22616.Fan WC, Qian P, Wang DD, Zhi XW, Wei YM, Chen HC, Li XM*. Integrin alpha v beta 3 promotes infection by Japanese encephalitis virus. Research In Veterinary Science. 2017, 111: 67-74 1.29817.Li YY, Zhou M, Luo ZC , Zhang YC, Cui M , Chen HC, Fu ZF, Zhao L*. Overexpression of Interleukin-7 Extends the Humoral Immune Response Induced by Rabies Vaccination. Journal Of Virology.2017, 91: 7 3.35418.Ye J, Chen Z, Li YC, Zhao ZK, He W, Zohaib A, Song YF, Deng CL, Zhang B, Chen HC, Cao Shengbo. Japanese Encephalitis Virus NS5 Inhibits Type I Interferon (IFN) Production by Blocking the Nuclear Translocation of IFN Regulatory Factor 3 and NF-kappa B. Journal Of Virology.2017, 91: 8 3.35419.Liu XK, Yang C, Hu Y, Lei EM, Lin X, Zhao LZ, Zou Z, Zhang AD, Zhou HB, Chen HC, Qian P*, Jin ML*. HIST1H1C Regulates Interferon-beta and Inhibits Influenza Virus Replication by Interacting with IRF3.Frontiers In Immunology. 2017, 8 6.4320.Li P, Wang R, Dong WQ, Hu LL, Zong BB, Zhang YY, Wang XG, Guo AZ, Zhang AD, Xiang YZ, Chen HC, Tan C*.Comparative Proteomics Analysis of Human Macrophages Infected with Virulent Mycobacterium bovis. Frontiers In Cellular And Infection Microbiology.2017, 7, DOI: 10.3389/fcimb.2017.00065 4.321.Yuan FY, Tan C , Liu ZW, Yang K, Zhou D, Liu W, Duan ZY, Guo R, Chen HC, Tian YX* , Bei WC*. The 1910HK/RR two-component system is essential for the virulence of Streptococcus suis serotype 2. Microbial Pathogenesis.2017, 104: 137-145 2.00922.Sun YX, Deng ML, Peng Z, Hu RM, Chen HC, Wu B*. Genetic and phylogenetic analysis of feline calicivirus isolates in China. Veterinary Journal. 2017, 220: 24-27 1.80223.Jing HY, Fang LR, Ding Z, Wang D, Hao WQ, Gao L, Ke WT, Chen HC, Xiao SB*. Porcine Reproductive and Respiratory Syndrome Virus nsp1 alpha Inhibits NF-kappa B Activation by Targeting the Linear Ubiquitin Chain Assembly Complex. Journal Of Virology.2017, 91: 3 3.35424.Wang Z, Li MM, Zhou M, Zhang YJ , Yang J, Cao YD, Wang KL, Cui M, Chen HC, Fu ZF, Zhao L*. A Novel Rabies Vaccine Expressing CXCL13 Enhances Humoral Immunity by Recruiting both T Follicular Helper and Germinal Center B Cells. Journal Of Virology.2017, 91: 3 3.35425.Fan WC, Liu TT, Li XM, Zhou Y, Wu MG, Cui XF, Chen HC, Qian P*. TRIM52: A nuclear TRIM protein that positively regulates the nuclear factor-kappa B signaling pathway. Molecular Immunology. 2017, 82: 114-122 3.23626.Jing Huiyuan, Fang Liurong, Ding Zhen, Wang Dang, Hao Wenqi, Gao Li, Ke Wenting, Chen Huanchun, Xiao Shaobo. Porcine Reproductive and Respiratory Syndrome Virus nsp1alpha Inhibits NF-kappaB Activation by Targeting the Linear Ubiquitin Chain Assembly Complex. Journal of virology.2017, 91:3 3.35427.Li YT, Ming F, Huang HM, Guo KL , Chen HC, Jin ML, Zhou HB*. Proteome Response of Chicken Embryo Fibroblast Cells to Recombinant H5N1 Avian Influenza Viruses with Different Neuraminidase Stalk Lengths. Scientific Reports.2017, 7 4.25928.Liu F, Fu JY, Liu CY, Chen J, Sun MH, Chen HC, Tan C*, Wang XR*. Characterization and distinction of two flagellar systems in extraintestinal pathogenic Escherichia coli PCN033. Microbiological.Research.2017, 196: 69-79 3.03729.Zheng CK, Ren SJ, Xu JL, Zhao XG, Shi GL, Wu JP, Li JQ, Chen HC, Bei WC*. Contribution of NADH oxidase to oxidative stress tolerance and virulence of Streptococcus suis serotype. Virulence.2017, 8(1): 53-65 4.66530.Chen YY, Wang JR, Ge P, Cao DJ, Miao BP, Robertson I, Zhou X, Zhang L, Chen HC, Guo AZ*. Tissue inhibitor of metalloproteinases 1 a novel biomarker of tuberculosis. Molecular Medicine Reports. 2017, 15(1): 483-487 1.69231.Farhan, Chen Yingyu, Hu Changmin, Chen Huanchun, Guo Aizhen*. Mycoplasma bovis NADH oxidase functions as both a NADH oxidizing and O2 reducing enzyme and an adhesin. Scientific reports. 2017, 7(1):44 4.258932.Peng Z, Liang W, Wang YG, Liu WJ, Zhang HF, Yu T, Zhang AD, Chen HC, Wu B*. Experimental pathogenicity and complete genome characterization of a pig origin Pasteurella multocida serogroup F isolate HN07. Veterinary Microbiology.2017, 198: 23-33 2.628
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